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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nefr</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology (Saint-Petersburg)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-6274</issn><issn pub-type="epub">2541-9439</issn><publisher><publisher-name>Pavlov First Saint-Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/1561-6274-2008-12-3-7-12</article-id><article-id custom-type="elpub" pub-id-type="custom">nefr-1113</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПЕРЕДОВАЯ СТАТЬЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LEADING ARTICLE</subject></subj-group></article-categories><title-group><article-title>ОСТРОЕ  ПОВРЕЖДЕНИЕ  ПОЧЕК  И  ОСТРАЯ  ПОЧЕЧНАЯ  НЕДОСТАТОЧНОСТЬ:  НЕКОТОРЫЕ  УРОКИ  МЕЖДУНАРОДНЫХ  ИНИЦИАТИВ</article-title><trans-title-group xml:lang="en"><trans-title>ACUTE  KIDNEY INJURY AND ACUTE  RENAL FAILURE:  SOME  LESSONS  FROM  INTERNATIONAL INITIATIVES</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Смирнов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Smirnov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Научно-исследовательский институт нефрологии,</p><p>кафедра пропедевтики внутренних болезней</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каюков</surname><given-names>И. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kayukov</surname><given-names>I. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Научно-исследовательский институт нефрологии,</p><p>кафедра нефрологии и диализа.</p><p>197022 Санкт-Петербург, ул. Л.Толстого 17, СПбГМУ им. акад. И.П. Павлова, Нефрокорпус, тел.: 812-3463926; факс: 812-2349191</p></bio><email xlink:type="simple">kaukov@nephrolog.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Добронравов</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Dobronravov</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Научно-исследовательский институт нефрологии,</p><p>кафедра пропедевтики внутренних болезней</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кучер</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kucher</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра пропедевтики внутренних болезней</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2008</year></pub-date><pub-date pub-type="epub"><day>10</day><month>03</month><year>2008</year></pub-date><volume>12</volume><issue>3</issue><fpage>7</fpage><lpage>12</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Смирнов А.В., Каюков И.Г., Добронравов В.А., Кучер А.Г., 2008</copyright-statement><copyright-year>2008</copyright-year><copyright-holder xml:lang="ru">Смирнов А.В., Каюков И.Г., Добронравов В.А., Кучер А.Г.</copyright-holder><copyright-holder xml:lang="en">Smirnov A.V., Kayukov I.G., Dobronravov V.A., Kucher A.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephrolog.ru/jour/article/view/1113">https://journal.nephrolog.ru/jour/article/view/1113</self-uri><abstract><p>В 2002 г группой экспертов Acute Dialysis Quality Initiative (ADQI) разработано определение острой почечной недостаточности (ОПН) и создана система стратификации ее тяжести (RIFLE-критерии). В 2004 г предложено понятие «острого повреждения почек» (ОПП), а в 2007 г исследовательской группой Acute Kidney Injury Network (AKIN) представлена система критериев диагностики и оценки выраженности данного состояния (AKIN-критерии), представляющая собой модификацию классификационной схемы RIFLE. Обе системы неплохо зарекомендовали себя на практике для прогнозирования развития ОПП и его исходов у пациентов, находящихся в критических состояниях. Однако ни схема RIFLE, ни схема AKIN первоначально не предполагали включение пациентов с острыми первичными паренхиматозными повреждениями почек, что не может устраивать нефрологическое сообщество. Предложена модификация системы AKIN, позволяющая устранить данное ограничение.</p></abstract><trans-abstract xml:lang="en"><p>In 2002 a group of experts Acute Dialysis Quality Initiative (ADQI) developed a definition of acute renal kidney failure (ARF) and created a system of its risk stratification. (RIFLE-criteria). In 2004 was proposed a conception of «acute injury» (AKI), and in 2007 an experimental group Acute Kidney Injury Network (AKIN) offered a diagnostic criteria system and evaluation of the degree of such condition (AKIN-criteria), which was a modification of RIFLE classification system. Both systems gave a good showing of themselves in practice for the prediction of the development of AKI and its outcome in patients in critical condition. However, not the RIFLE system, nor the AKIN system initially did not suppose to include the patients with acute primary parenchymatous renal damage, which does not satisfy the nephrological community. A modification of the AKIN system, which allows to dismiss such limitation, was proposed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>острое повреждение почек</kwd><kwd>острая почечная недостаточность</kwd><kwd>определение</kwd><kwd>классификация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>acute kidney injury</kwd><kwd>acute renal failure</kwd><kwd>definition</kwd><kwd>classification</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Waikar SS, Liu KD, Chertow GM. Diagnosis, epidemiology and outcomes of acute kidney injury. Clin J Am Soc Nephrol 2008; 3(3):844-861</mixed-citation><mixed-citation xml:lang="en">Waikar SS, Liu KD, Chertow GM. Diagnosis, epidemiology and outcomes of acute kidney injury. 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