nefrНефрологияNephrology (Saint-Petersburg)1561-62742541-9439Pavlov First Saint-Petersburg State Medical University10.24884/1561-6274-2008-12-3-36-55nefr-1117Research ArticleОРИГИНАЛЬНЫЕ СТАТЬИ. КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯORIGINAL ARTICLES. CLINICAL INVESTIGATIONSСОСТОЯНИЕ ФУНКЦИИ ПОЧЕК У МУЖЧИН С КОРОНАРНОЙ БОЛЕЗНЬЮ СЕРДЦАTHE STATE OF RENAL FUNCTION IN MALES WITH CORONARY HEART DISEASEКаюковИ. Г.KayukovI. G.

кафедра нефрологии и диализа

197022 Санкт-Петербург, ул. Л. Толстого 17, СПбГМУ им. акад. И.П. Павлова, “Нефрокорпус”, тел.: (812)-346-39-26, факс: (812)-234-91-91

kaukov@nephrolog.ruСмирновА. В.SmirnovA. V.

кафедра пропедевтики внутренних болезней

СедовВ. М.SedovV. M.

кафедра факультетской хирургии

Од-ЭрдэнеЛхаахууOd-ErdeneLhaahuu

кафедра пропедевтики внутренних болезней

 

ДудаевА. В.DulaevA. V.

кафедра факультетской хирургии

ПизинВ. М.PizinV. M.

кафедра факультетской хирургии

Санкт-Петербургский государственный медицинский университет им. акад. И.П. ПавловаRussian Federation2008100320081233655Copyright © Каюков И.Г., Смирнов А.В., Седов В.М., Од-Эрдэне Л., Дудаев А.В., Пизин В.М., 20082008Каюков И.Г., Смирнов А.В., Седов В.М., Од-Эрдэне Л., Дудаев А.В., Пизин В.М.Kayukov I.G., Smirnov A.V., Sedov V.M., Od-Erdene L., Dulaev A.V., Pizin V.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.nephrolog.ru/jour/article/view/1117

ЦЕЛЬ РАБОТЫ. Проанализировать взаимоотношения между выраженностью повреждений коронарных артерий и уровнем расчетной скорости клубочковой фильтрации (рСКФ) у мужчин с ишемической болезнью сердца (ИБС) без признаков «первичной» почечной патологии с учетом влияния ряда традиционных факторов риска сердечно-сосудистой болезни (артериальная гипертензия, дислипидемия, возраст, табакокурение). ПАЦИЕНТЫ И МЕТОДЫ. Обследовано 300 пациентов-мужчин с ИБС, подтвержденной коронарной ангиографией (КА). Результаты КА оценены с помощью полуколичественных методов. РЕЗУЛЬТАТЫ. Тяжесть повреждений коронарного русла оказалась тесно обратно связана с величиной рСКФ, уровнем артериальной гипертензии, возрастом и некоторыми показателями липидограммы сыворотки крови. Величины рСКФ у курящих пациентов с ИБС оказались значимо ниже, чем у никогда не куривших. ЗАКЛЮЧЕНИЕ. Результаты исследования свидетельствуют о том,  что  почечная дисфункция  весьма часто встречается у пациентов с  ИБС,  не имеющих явных признаков «первичной» патологии почек.  При этом такие факторы как выраженность артериальной гипертензии, дислипидемия, возраст и привычка к табакокурению, по-видимому, выступают в качестве предикторов не только тяжести коронарного атеросклероза, но и почечного повреждения у таких больных.

THE AIM. To analyze the interactions between the damage degree of coronary arteries and the calculated glomerular filtration rate (GFR) in males with ischemic cardiac disease (CHD) without the signs of «primary» renal pathology, taking into consideration the influence of various traditional risk factors of cardio-vascular disease (arterial hypertension, dislipidemia, age, smoking). PATIENTS AND METHODS. 300 males suffering from CHD, with proven coronary angiography (CA) were evaluated. The results of CA were evaluated with semiquantative methods. RESULTS. The severity of the coronary channel damage was in reverse connection with the values of GFR, arterial hypertension levels, age and some figures of blood serum lipidogram. The values of GFR of smoking patients with CHD were much lower, than of ones never smoked. CONCLUSION. The results of the investigation show that the renal dysfunction is often seen in patients with CHD, while they do not have the obvious signs of «primary» renal pathology. And with that, such factors as extend of arterial hypertension,  dislipidemia, age and smoking habits,  probably, act as the predictors,  not only of the severity of the coronary arteriosclerosis,  but also of a renal damage in such patients.

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The authors declare that there are no conflicts of interest present.