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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nefr</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology (Saint-Petersburg)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-6274</issn><issn pub-type="epub">2541-9439</issn><publisher><publisher-name>Pavlov First Saint-Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/1561-6274-2009-13-1-107-111</article-id><article-id custom-type="elpub" pub-id-type="custom">nefr-1157</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИСТОРИЯ МЕДИЦИНЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>HISTORY OF MEDICINE</subject></subj-group></article-categories><title-group><article-title>БОЛГАРСКИЙ ВКЛАД В УЧЕНИЕ О ПРОБИОТИКАХ: СТАМЕН ГРИГОРОВ И ЕГО ЗНАМЕНИТОЕ ОТКРЫТИЕ БАКТЕРИИ LACTOBACILLUS BULGARICUS</article-title><trans-title-group xml:lang="en"><trans-title>BULGARIAN  PARTICIPATION  IN THE  PROBIOTIC STUDY:  STAMEN  GRIGOROV AND  HIS  FAMOUS  DISCOVERY OF  LACTOBACILLUS BULGARICUS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Георгиева</surname><given-names>М.</given-names></name><name name-style="western" xml:lang="en"><surname>Georgieva</surname><given-names>M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра фармакологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Паскалев</surname><given-names>Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Paskalev</surname><given-names>D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>отделение нефрологии и гемодиализа</p><p>55 Marin Drinov Str., Varna, 9002, Bulgaria; Tel: +359 52 302 851, int.296</p></bio><bio xml:lang="en"><p>Clinic of Nephrology and Dialysis University Hospital «St. Marina»</p><p>55 Marin Drinov Str., Varna, 9002, Bulgaria; Tel: +359 52 302 851, int.296</p></bio><email xlink:type="simple">dobrinpaskalev@yahoo.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Медицинский университет «Проф. д-р Параскев Стоянов», г. Варна</institution><country>Болгария</country></aff><aff xml:lang="en"><institution>Medical University «Prof. Dr. P. Stoyanov», Varna</institution><country>Bulgaria</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>10</day><month>01</month><year>2009</year></pub-date><volume>13</volume><issue>1</issue><fpage>107</fpage><lpage>111</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Георгиева М., Паскалев Д., 2009</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="ru">Георгиева М., Паскалев Д.</copyright-holder><copyright-holder xml:lang="en">Georgieva M., Paskalev D.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephrolog.ru/jour/article/view/1157">https://journal.nephrolog.ru/jour/article/view/1157</self-uri><abstract><p>Исследователь Доктор Стамен Григоров (1878-1945) обучается на биологии в Монпельере (Франция) и после в последующем – медицине в Женеве (Швецария), окончив свое обучение в 1905 году. После систематического изучения Болгарского йогурта в 1905 году, он выделил бактерию приводящую к его брожению, которая была названа в его честь. За свое открытие он получает почетный диплом и премии в Университете Женевы и Институте Луи Пастера. Он отклоняет предложение занять пост ведущего специалиста в Женеве и Сан-Паyлy (Бразилия), и возвращается в Болгарию, где работает в качестве окружного и главного врача в госпитале в Тране. Во время Балканской и Первой мировой войны он принимал участие в борьбе против холеры и был удостоен военного креста и Золотого Красного Креста. Он разработал простивотуберкулезную вакцину, использовавшуюся в Институте Карло Форланини в Риме (1935).</p></abstract><trans-abstract xml:lang="en"><p>The discoverer Dr Stamen Grigorov (1878-1945) studies the natural sciences in Montpellier (France) and afterwards – medicine in Geneva (Switzerland), where he graduated in 1905. After systematic examinations of the Bulgarian yoghourt in 1905, he isolated the agent of souring, which is called in his honour. He receives for this discovery an honorary diploma and awards by Geneva University and Luis Pastcur Institute. He declines offers about leader’s work in Geneva and Sao Paolo (Brazil), he returns to Bulgaria and works as a district and head doctor at hospital in Tran. During the Balkan and First World War conlributed to the struggle against the cholera and he is awarded with military cross and Golden Red Cross. He created in his antituberculosis vaccine that used at Carlo Forlanini Institute in Rome (1935).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Стамен Григоров</kwd><kwd>lactobacillus bulgaricus</kwd><kwd>история</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Stamen Grigorov</kwd><kwd>lactobacillus bulgaricus</kwd><kwd>history</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Гълъбов A. 100 години от откритието на L. Bulgaricus Grigoroff. Интернационален симпозиум за оригиналното българско кисело мляко. София, 25-27, май 2005</mixed-citation><mixed-citation xml:lang="en">Гълъбов A. 100 години от откритието на L. Bulgaricus Grigoroff. Интернационален симпозиум за оригиналното българско кисело мляко. София, 25-27, май 2005</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Александров Н. 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