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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nefr</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology (Saint-Petersburg)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-6274</issn><issn pub-type="epub">2541-9439</issn><publisher><publisher-name>Pavlov First Saint-Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/1561-6274-2009-13-3-24-32</article-id><article-id custom-type="elpub" pub-id-type="custom">nefr-1174</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>ЭНДОТЕЛИАЛЬНАЯ ДИСФУНКЦИЯ, МЕТАБОЛИЧЕСКИЙ СИНДРОМ И МИКРОАЛЬБУМИНУРИЯ</article-title><trans-title-group xml:lang="en"><trans-title>ENDOTHELIAL DYSFUNCTION, METABOLIC SYNDROME AND MICROALBUMINURIA</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шишкин</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Shishkin</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра терапии Медицинского факультета</p></bio><email xlink:type="simple">alexshishkin@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лындина</surname><given-names>М. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Lyndina</surname><given-names>M. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра терапии Медицинского факультета</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Санкт-Петербургский государственный университет</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>10</day><month>03</month><year>2009</year></pub-date><volume>13</volume><issue>3</issue><fpage>24</fpage><lpage>32</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шишкин А.Н., Лындина М.Л., 2009</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="ru">Шишкин А.Н., Лындина М.Л.</copyright-holder><copyright-holder xml:lang="en">Shishkin A.N., Lyndina M.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephrolog.ru/jour/article/view/1174">https://journal.nephrolog.ru/jour/article/view/1174</self-uri><abstract><p>В статье представлены данные о патогенезе возникновения дисфункции эндотелия при метаболическом синдроме. Описаны клинические и патогенетические особенности эндотелиальной дисфункции. Освещена проблема методов диагностики функции эндотелия. Показана роль микроальбуминурии. Представлены возможные подходы к терапии.</p></abstract><trans-abstract xml:lang="en"><p>The article presents the data on pathogenesis of endothelial dysfunction in metabolic syndrome. Clinical and pathogenetic features of endothelial dysfunction are described. The problem of methods for diagnostics of endothelial dysfunction is covered. The role of microalbuminuria is shown. Probable approaches to the treatment of endothelial dysfunction are submitted.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>метаболический синдром</kwd><kwd>эндотелиальная дисфункция</kwd><kwd>микроальбуминурия</kwd><kwd>эндотелий-зависимая вазодилатация</kwd><kwd>подходы к лечению</kwd></kwd-group><kwd-group xml:lang="en"><kwd>metabolic syndrome</kwd><kwd>endothelial dysfunction</kwd><kwd>microalbuminuria</kwd><kwd>endothelium-dependent vasodilation</kwd><kwd>probable approaches to therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Строев ЮИ, Цой МВ, Чурилов ЛП, Шишкин АН. Классические и современные представления о метаболическом синдроме. Часть 1. Критерии, эпидемиология, этиология. Вестник СПбГУ, серия 11; 2007 (1): 13-16</mixed-citation><mixed-citation xml:lang="en">Строев ЮИ, Цой МВ, Чурилов ЛП, Шишкин АН. 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