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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nefr</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology (Saint-Petersburg)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-6274</issn><issn pub-type="epub">2541-9439</issn><publisher><publisher-name>Pavlov First Saint-Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/1561-6274-2010-14-3-52-57</article-id><article-id custom-type="elpub" pub-id-type="custom">nefr-1231</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЖУРНАЛ В ЖУРНАЛЕ. АКТУАЛЬНЫЕ ПРОБЛЕМЫ УРОЛОГИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>JOURNAL IN THE JOURNAL. ACTUAL PROBLEMS OF UROLOGY</subject></subj-group></article-categories><title-group><article-title>НАРУШЕНИЕ СОКРАТИМОСТИ ДЕТРУЗОРА У БОЛЬНЫХ ДОБРОКАЧЕСТВЕННОЙ ГИПЕРПЛАЗИЕЙ ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫ</article-title><trans-title-group xml:lang="en"><trans-title>DETRUSOR CONTRACTILITY DISORDERS IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аль-Шукри</surname><given-names>С. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Al-Shukri</surname><given-names>S. Kh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра урологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Амдий</surname><given-names>Р. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Amdiy</surname><given-names>R. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра урологии</p><p>197022, Санкт-Петербург, ул. Льва Толстого, д. 17, кафедра урологии Санкт-Петербургского государственного ме­дицинского университета им. акад. И.П. Павлова; тел.: (812) 234­-19-54.</p></bio><email xlink:type="simple">R.E.Amdiy@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузьмин</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuzmin</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра урологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дарагма</surname><given-names>Г. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Daragma</surname><given-names>G. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра урологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>10</day><month>03</month><year>2010</year></pub-date><volume>14</volume><issue>3</issue><fpage>52</fpage><lpage>57</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Аль-Шукри С.Х., Амдий Р.Э., Кузьмин И.В., Дарагма Г.И., 2010</copyright-statement><copyright-year>2010</copyright-year><copyright-holder xml:lang="ru">Аль-Шукри С.Х., Амдий Р.Э., Кузьмин И.В., Дарагма Г.И.</copyright-holder><copyright-holder xml:lang="en">Al-Shukri S.K., Amdiy R.E., Kuzmin I.V., Daragma G.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephrolog.ru/jour/article/view/1231">https://journal.nephrolog.ru/jour/article/view/1231</self-uri><abstract><p>ЦЕЛЬ ИССЛЕДОВАНИЯ. Оценка нарушений сократимости детрузора у больных доброкачественной гиперплазией предстательной железы (ДГПЖ). ПАЦИЕНТЫ И МЕТОДЫ. Для определения сократимости детрузора 146 больным с ДГПЖ, средний возраст 62,1±0,8 года, было проведено комплексное урологическое обследование, включавшее уродинамическое исследование с выполнением урофлоуметрии и микционной цистометрии (исследование «давление–поток»). Интерпретацию результатов микционной цистометрии проводили по номограмме W. Shafer, также был определен индекс опорожнения мочевого пузыря как процентное отношение объема мочеиспускания к максимальной цистометрической емкости мочевого пузыря. РЕЗУЛЬТАТЫ. Снижение сократимости детрузора было выявлено у 56,2% обследованных больных с ДГПЖ. Результаты определения сократимости мочевого пузыря по номограмме Шафера зависят от степени инфравезикальной обструкции (ИВО). Индекс опорожнения мочевого пузыря не зависит от наличия и степени ИВО и характеризует как степень опорожнения мочевого пузыря, так и длительность сокращения. Наличие такой сопутствующей патологии, как остеохондроз поясничного отдела позвоночника и сахарный диабет, ухудшает опорожнение мочевого мочевого пузыря. Оценка сократимости достоверно может быть проведена только на основе уродинамического исследования, так как при оценке сократимости детрузора результаты общепринятого обследования больных с ДГПЖ малоинформативны. ЗАКЛЮЧЕНИЕ. У значительного количества больных с ДГПЖ нарушение функции нижних мочевых путей обусловлено не наличием инфравезикальной обструкции, а снижением сократимости мочевого пузыря, что следует учитывать при определении тактики лечения.</p></abstract><trans-abstract xml:lang="en"><p>THE GOAL of the study was evaluation of detrusor contractility disorders in patients with benign prostatic hyperplasia (BPH). PATIENTS AND METHODS. 146 patients were undergone urodynamic investigations including urofluometry and miction cystometry (pressure-flow testing). Miction cystometry data obtained was further interpreted by W.Shafer nomogram. Bladder emptying index as ratio of urine voiding volume to maximal bladder volume by cystometry was determined as well. RESULTS. Decrease of detrusor contractility has been found in 56,2% of patients with BPH. Bladder contractility data, as determined by W.Shafer nomogram, depends on degree of infravesical obstruction (IVO). Bladder emptying index characterizing both degree of bladder emptying and duration of contraction does not depend on the presence and degree of IVO. Presence of lumbar osteoarthrosis and diabetes mellitus aggravate bladder emptying. CONCLUSION. In a significant proportion of patients with BPH disorders of lower urinary tract function are stipulated by the decrease of bladder contractility, but not by IVO, that should be considered in a treatment decision.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>доброкачественная гиперплазия предстательной железы</kwd><kwd>уродинамические исследования</kwd><kwd>сократимость детрузора</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Benign prostatic hyperplasia</kwd><kwd>urodynamic study of detrusor contractility</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Thomas AW, Cannon A, Bartlett E et al. The natural history of lower urinary tract dysfunction in men: the influence of detrusor underactivity on the outcome after transurethral resection of the prostate with minimum 10-year urodynamic follow-up. BJU International 2004; 93:745-750</mixed-citation><mixed-citation xml:lang="en">Thomas AW, Cannon A, Bartlett E et al. The natural history of lower urinary tract dysfunction in men: the influence of detrusor underactivity on the outcome after transurethral resection of the prostate with minimum 10-year urodynamic follow-up. BJU International 2004; 93:745-750</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Abrams P, Cardozo L, Fall M et al. The standardisation of terminology in lower urinary tract function : report from the Standardisation Sub-committee of the International Continence Society. Neurourol Urodynam 2002; 21 (2): 167-178</mixed-citation><mixed-citation xml:lang="en">Abrams P, Cardozo L, Fall M et al. The standardisation of terminology in lower urinary tract function : report from the Standardisation Sub-committee of the International Continence Society. Neurourol Urodynam 2002; 21 (2): 167-178</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Shafer W. Basic principles and clinical application of advanced analysis of bladder voiding function. Urol Clin North Am 1990; 17 (2): 553-566</mixed-citation><mixed-citation xml:lang="en">Shafer W. Basic principles and clinical application of advanced analysis of bladder voiding function. Urol Clin North Am 1990; 17 (2): 553-566</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Abrams P. Bladder outlet obstruction index, blader contractility index and bladder voiding efficiency: three simple indices to define bladder voiding function. BJU International 1999; 84: 745-750</mixed-citation><mixed-citation xml:lang="en">Abrams P. Bladder outlet obstruction index, blader contractility index and bladder voiding efficiency: three simple indices to define bladder voiding function. BJU International 1999; 84: 745-750</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Schafer W, Abrams P, Liao L et al. Good urodynamic practices: uroflowmetry, filling cystometry, and pressure-flow studies. Neurourol Urodyn 2002; 21(3): 261-274</mixed-citation><mixed-citation xml:lang="en">Schafer W, Abrams P, Liao L et al. Good urodynamic practices: uroflowmetry, filling cystometry, and pressure-flow studies. Neurourol Urodyn 2002; 21(3): 261-274</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Kaplan SA, Te AE, Blaivas JG. Urodynamic findings in patients with diabetic cystopathy. J Urol 1995; 153: 342-344</mixed-citation><mixed-citation xml:lang="en">Kaplan SA, Te AE, Blaivas JG. Urodynamic findings in patients with diabetic cystopathy. J Urol 1995; 153: 342-344</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Yamamoto T, Sakakibara R, Uchiyama T et al. Neurological diseases that cause detrusor hyperactivity with impaired contractile function.Neurourol Urodyn 2006; 25 (2): 119-123</mixed-citation><mixed-citation xml:lang="en">Yamamoto T, Sakakibara R, Uchiyama T et al. Neurological diseases that cause detrusor hyperactivity with impaired contractile function.Neurourol Urodyn 2006; 25 (2): 119-123</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Chancellor MB, Rivas DA, Keeley F et al. Similarity of the American Urological Association symptom index among men with benign prostatic hyperplasia, urethral obstruction not due to BPH and detrusor instability without bladder outlet obstruction. Br J Urol 1994; 74 (2): 200-203</mixed-citation><mixed-citation xml:lang="en">Chancellor MB, Rivas DA, Keeley F et al. Similarity of the American Urological Association symptom index among men with benign prostatic hyperplasia, urethral obstruction not due to BPH and detrusor instability without bladder outlet obstruction. Br J Urol 1994; 74 (2): 200-203</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Hindley RG, Brierly RD, McLarty E et al. A qualitative ultrastructural study of the hypocontractile detrusor. J Urol 2002;168(1): 126-131</mixed-citation><mixed-citation xml:lang="en">Hindley RG, Brierly RD, McLarty E et al. A qualitative ultrastructural study of the hypocontractile detrusor. J Urol 2002;168(1): 126-131</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Steele GS, Sullivan MP, Sleep DJ, Yalla SV. Combination of symptom score, flow rate and prostate volume for predicting bladder outflow obstruction in men with lower urinary tract symptoms. J Urol 2000; 164 (2): 344-348</mixed-citation><mixed-citation xml:lang="en">Steele GS, Sullivan MP, Sleep DJ, Yalla SV. Combination of symptom score, flow rate and prostate volume for predicting bladder outflow obstruction in men with lower urinary tract symptoms. J Urol 2000; 164 (2): 344-348</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Chancellor MB, Blaivas JG, Kaplan SA, Axelrod S. Bladder outlet obstruction versus impaired detrusor contractility: the role of outflow. J Urol 1991; 145(4): 810-812</mixed-citation><mixed-citation xml:lang="en">Chancellor MB, Blaivas JG, Kaplan SA, Axelrod S. Bladder outlet obstruction versus impaired detrusor contractility: the role of outflow. J Urol 1991; 145(4): 810-812</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Van Venrooij GE, Eckhardt MD, Boon TA. Data from frequency-volume charts versus maximum free flow rate, residual volume, and voiding cystometric estimated urethral obstruction grade and detrusor contractility grade in men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia. Neurourol Urodyn 2002; 21(5): 450-456</mixed-citation><mixed-citation xml:lang="en">Van Venrooij GE, Eckhardt MD, Boon TA. Data from frequency-volume charts versus maximum free flow rate, residual volume, and voiding cystometric estimated urethral obstruction grade and detrusor contractility grade in men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia. Neurourol Urodyn 2002; 21(5): 450-456</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
