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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nefr</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology (Saint-Petersburg)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-6274</issn><issn pub-type="epub">2541-9439</issn><publisher><publisher-name>Pavlov First Saint-Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/1561-6274-2010-14-4-89-95</article-id><article-id custom-type="elpub" pub-id-type="custom">nefr-1250</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПРОГРАММА НЕПРЕРЫВНОГО ПОСЛЕДИПЛОМНОГО ОБРАЗОВАНИЯ ПО НЕФРОЛОГИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PROGRAM ON CONTINUOUS POSTGRADUATE EDUCATION ON NEPHROLOGY</subject></subj-group></article-categories><title-group><article-title>ИЗУЧЕНИЕ КЛИНИЧЕСКОГО СЛУЧАЯ. ТЯЖЁЛАЯ ГИПОНАТРИЕМИЯ С ВЫСОКИМ СОДЕРЖАНИЕМ НАТРИЯ В МОЧЕ И ОСМОЛЯЛЬНОСТЬЮ</article-title><trans-title-group xml:lang="en"><trans-title>CLINICAL CASE STUDY. SEVERE HYPONATREMIA WITH HIGH URINE SODIUM AND OSMOLALITY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>ван дер Хук</surname><given-names>Йуст</given-names></name><name name-style="western" xml:lang="en"><surname>Van der Hoek</surname><given-names>Joost</given-names></name></name-alternatives><bio xml:lang="ru"><p>Отдел внутренней медицины</p><p>Erasmus Medical Center, Department of Internal Medicine, P.O. Box 2040, 3000 CA Rotterdam, the Netherlands. Fax +31-10-7031146.</p></bio><bio xml:lang="en"><p>Department of Internal Medicine,</p><p>P.O. Box 2040, 3000  CA Rotterdam, the Netherlands. Fax +31-10-7031146.</p></bio><email xlink:type="simple">j.vanderhoek@erasmusmc.nl</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хум</surname><given-names>Евонт Дж.</given-names></name><name name-style="western" xml:lang="en"><surname>Hoorn</surname><given-names>Ewout J.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Отдел внутренней медицины</p></bio><bio xml:lang="en"><p>Department of Internal Medicine</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>де Йонг</surname><given-names>Гийс М.Т.</given-names></name><name name-style="western" xml:lang="en"><surname>De Jong</surname><given-names>Gijs M.T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Отдел внутренней медицины</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Йанссенс</surname><given-names>Эмиль Н.В.</given-names></name><name name-style="western" xml:lang="en"><surname>Janssens</surname><given-names>Emile N.W.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Отдел внутренней медицины</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>де Хердер</surname><given-names>Воутер В.</given-names></name><name name-style="western" xml:lang="en"><surname>De Herder</surname><given-names>Wouter W.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Отдел внутренней медицины</p></bio><bio xml:lang="en"><p>Department of Internal Medicine</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Медицинский Центр Эрасмуса, г. Роттердам</institution><country>Нидерланды</country></aff><aff xml:lang="en"><institution>Erasmus  Medical  Center, Rotterdam</institution><country>Netherlands</country></aff></aff-alternatives><aff xml:lang="ru" id="aff-2"><institution>Клиника Альберта Швейтцера, г. Дордрехт</institution><country>Netherlands</country></aff><aff xml:lang="ru" id="aff-3"><institution>Клиника Алберта Швейтцера, г. Дордрехт</institution><country>Netherlands</country></aff><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>10</day><month>04</month><year>2010</year></pub-date><volume>14</volume><issue>4</issue><fpage>89</fpage><lpage>95</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; ван дер Хук Й., Хум Е., де Йонг Г., Йанссенс Э., де Хердер В., 2010</copyright-statement><copyright-year>2010</copyright-year><copyright-holder xml:lang="ru">ван дер Хук Й., Хум Е., де Йонг Г., Йанссенс Э., де Хердер В.</copyright-holder><copyright-holder xml:lang="en">van der Hoek J., Hoorn E., de Jong G., Janssens E., de Herder W.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephrolog.ru/jour/article/view/1250">https://journal.nephrolog.ru/jour/article/view/1250</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>первичная недостаточность коры надпочечников</kwd><kwd>синдром неадекватной секреции антидиуретического гормона (СНСАДГ)</kwd><kwd>гипонатриемия</kwd><kwd>осмоляльность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>primary adrenal insufficiency</kwd><kwd>syndrome of inappropriateantidiuretic hormone secretion (SIADH)</kwd><kwd>hyponatremia</kwd><kwd>osmolality</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Hoorn EJ, Zietse R. 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