nefrНефрологияNephrology (Saint-Petersburg)1561-62742541-9439Pavlov First Saint-Petersburg State Medical Universitynefr-152Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESВАКЦИНАЦИЯ ДЕТЕЙ С ЗАБОЛЕВАНИЯМИ ПОЧЕКVACCINATION IN CHILDREN WITH RENAL DISEASEКостиновМихаил ПетровичKostinovMikhail P.insvact@gmail.comРуснакФедор ИвановичRusnakFyodor I.fedor_rusnak@mail.ruНаучно-исследовательский институт вакцин и сывороток им. И.И.МечниковаRussian FederationДепартамент здравоохранения г. МосквыRussian Federation2016010120162012435Copyright © Костинов М.П., Руснак Ф.И., 20162016Костинов М.П., Руснак Ф.И.Kostinov M.P., Rusnak F.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.nephrolog.ru/jour/article/view/152

Вакцинация является краеугольным камнем предупреждения развития инфекций у детей с заболеваниями почек. Дети с хроническими заболеваниями почек должны вакцинироваться согласно календарю, как и здоровые дети. Учитывая высокий риск развития инфекций, предупреждаемых вакцинацией после трансплантации почек, полная вакцинация особенно необходима пациентам с хронической болезнью почек С5 стадии. Предупреждение и мониторирование инфекций у детей с заболеваниями почек является комплексной проблемой в успешной почечной трансплантации.

One of the cornerstones of preventive care in pediatric renal disease is delivery of routine childhood immunization. Children with chronic kidney disease should receive immunization according to the recommendation for healthy children. Given the increased risk for vaccine-preventable disease post-transplantation, complete immunization is especially important in children with chronic kidney disease С5 as they approach transplantation. The prevention and monitoring of infection in children with renal disease are complex but are critical to the ultimate success of the transplantation.

вакцинациязаболевания почекгломерулонефритнефротический синдромпиелонефритинфекция мочевой системыдетихроническая болезнь почекдиализтрансплантацияvaccinationkidney diseasechildrenglomerulonephritisnephrotic syndromeurinary tract infectionpyelonephritischronic kidney diseasedialysistransplantationReferencesChaves TSS, Pereira LM, Santos SDe S et al. Evaluation of the vaccination status in pediatric renal transplant recipients. Pediatr Transplant. 2008; 12(4):432-435Chaves TSS, Pereira LM, Santos SDe S et al. Evaluation of the vaccination status in pediatric renal transplant recipients. Pediatr Transplant. 2008; 12(4):432-435Fivush B.A., Case B, Waraby BA, Lederman H. Defective antibody response to Hemophilus influenzae type b immunization in children receiving peritoneal dialysis. Pediatr. Nephrol. 1993; 7 (5): 548 - 550Fivush B.A., Case B, Waraby BA, Lederman H. Defective antibody response to Hemophilus influenzae type b immunization in children receiving peritoneal dialysis. Pediatr. Nephrol. 1993; 7 (5): 548 - 550Neuhaus T.J. Immunization in children with chronic renal failure: a practical approach. Pediatr. Nephrol. 2004; 19 (12): 1334 -1339Neuhaus T.J. Immunization in children with chronic renal failure: a practical approach. Pediatr. Nephrol. 2004; 19 (12): 1334 -1339Cohn J, Blumberg EA. Immunizations for renal transplant candidates and recipients. Nat. Clin. Pract. Nephrol. 2009; 5(1): 46 - 53Cohn J, Blumberg EA. Immunizations for renal transplant candidates and recipients. Nat. Clin. Pract. Nephrol. 2009; 5(1): 46 - 53Смирнов А.В., Добронравов В.А., Каюков И.Г. и др. Хроническая болезнь почек: основные принципы скрининга, диагностики, профилактики и подходы к лечению. Национальные рекомендации. Нефрология. 2012;16(1):89-115 [Smirnov A.V., Dobronravov V.A., Kayukov I.G. i dr. Khronicheskaya bolezn’ pochek: osnovnye printsipy skrininga, diagnostiki, profilaktiki i podkhody k lecheniyu. Natsional’nye rekomendatsii. Nefrologiya. 2012;16(1):89-115]Смирнов А.В., Добронравов В.А., Каюков И.Г. и др. Хроническая болезнь почек: основные принципы скрининга, диагностики, профилактики и подходы к лечению. Национальные рекомендации. Нефрология. 2012;16(1):89-115 [Smirnov A.V., Dobronravov V.A., Kayukov I.G. i dr. Khronicheskaya bolezn’ pochek: osnovnye printsipy skrininga, diagnostiki, profilaktiki i podkhody k lecheniyu. Natsional’nye rekomendatsii. Nefrologiya. 2012;16(1):89-115]Barril G, Teruel JL. Vaccination scheme in advanced chronic kidney disease. Nefrologia. 2008; 28 (3): 95 - 99Barril G, Teruel JL. Vaccination scheme in advanced chronic kidney disease. Nefrologia. 2008; 28 (3): 95 - 99CDC. Kidney Dialisis Patents and Patients with Chronic Kidney Disease: summarized from Recommendation of the Advisory Committee on Immunization Practices (ACIP) MMWR 2006; 55; RR-10CDC. Kidney Dialisis Patents and Patients with Chronic Kidney Disease: summarized from Recommendation of the Advisory Committee on Immunization Practices (ACIP) MMWR 2006; 55; RR-10CDC. Prevention and Control of Influenza Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR 2009; 58; RR-16: 1-25RCDC. Prevention and Control of Influenza Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR 2009; 58; RR-16: 1-25RCDC. A Comprehensive Immunization Strategy to Eliminate Transmission of Hepatitis B Virus Infection in the United States: Recommendations of the Advisory Committee on Immunization Practices (ACIP) Part II: Immunization of Adults. MMWR 2006; 55 (No. R16): 1-25CDC. A Comprehensive Immunization Strategy to Eliminate Transmission of Hepatitis B Virus Infection in the United States: Recommendations of the Advisory Committee on Immunization Practices (ACIP) Part II: Immunization of Adults. MMWR 2006; 55 (No. R16): 1-25Chow KM, Law MC, Leung CB et al. Antibody response to hepatitis b vaccine in end-stage renal disease patients. Nephron. Clin. Pract. 2006; 103 (3): 89-93Chow KM, Law MC, Leung CB et al. Antibody response to hepatitis b vaccine in end-stage renal disease patients. Nephron. Clin. Pract. 2006; 103 (3): 89-93Sun L, Xu H, Zhan LJ et al. Effect of hepatitis B vaccine imnization on HBV associated nephritis in children. Zhonghma Er. Kl. Za. Zhi. 2003; 41 (9): 666 -669.Sun L, Xu H, Zhan LJ et al. Effect of hepatitis B vaccine imnization on HBV associated nephritis in children. Zhonghma Er. Kl. Za. Zhi. 2003; 41 (9): 666 -669.Bel’eed K, Wrigth M, Eadington D et al. Vaccination against hepatitis B infection in patients with end stage renal disease. Post-grad. Med. J. 2002; 78: 538 -540Bel’eed K, Wrigth M, Eadington D et al. Vaccination against hepatitis B infection in patients with end stage renal disease. Post-grad. Med. J. 2002; 78: 538 -540Тарасова АА. Состояние специфического иммунитета у детей с иммунопатологическими заболеваниями, вакцинированных в рамках календаря прививок, и клинико-иммунологический эффект бактериальной и гриппозной вакцин: автореф. дисс.. д-ра мед. наук: 14.00.09, 14.00.36. Н.Новгород, 2006.- 46 с [Tarasova AA. Sostoyanie spetsificheskogo immuniteta u detey s immunopatologicheskimi zabolevaniyami, vaktsinirovannykh v ramkakh kalendarya privivok, i kliniko - immunologicheskiy effekt bakterial'noy i grippoznoy vaktsin: avtoref. diss. dokt. med. nauk: 14.00.09, 14.00.36. N.Novgorod, 2006.- 46 s]Тарасова АА. Состояние специфического иммунитета у детей с иммунопатологическими заболеваниями, вакцинированных в рамках календаря прививок, и клинико-иммунологический эффект бактериальной и гриппозной вакцин: автореф. дисс.. д-ра мед. наук: 14.00.09, 14.00.36. Н.Новгород, 2006.- 46 с [Tarasova AA. Sostoyanie spetsificheskogo immuniteta u detey s immunopatologicheskimi zabolevaniyami, vaktsinirovannykh v ramkakh kalendarya privivok, i kliniko - immunologicheskiy effekt bakterial'noy i grippoznoy vaktsin: avtoref. diss. dokt. med. nauk: 14.00.09, 14.00.36. N.Novgorod, 2006.- 46 s]Szajner-Melart J, Zajaczkowska M, Zinkiewicz Z et al. Efficacy of vaccination against viral hepatitis type B in children with the nephritic syndrome. Ann. Univ. Maria Curie Sklodowska(Med) 2003; 58 (1): 402 -408Szajner-Melart J, Zajaczkowska M, Zinkiewicz Z et al. Efficacy of vaccination against viral hepatitis type B in children with the nephritic syndrome. Ann. Univ. Maria Curie Sklodowska(Med) 2003; 58 (1): 402 -408Bhimma R, Coovadia HM Hepatitis B virus-associated nephropathy. Am. J. Nephrol. 2004; 24 (2): 198 - 211Bhimma R, Coovadia HM Hepatitis B virus-associated nephropathy. Am. J. Nephrol. 2004; 24 (2): 198 - 211Berger A, Preiser W, Kachel HF, et al. HBV revaccination after kidney transplantation. J. Clin. Virol. 2005; 32 (20: 162 - 165Berger A, Preiser W, Kachel HF, et al. HBV revaccination after kidney transplantation. J. Clin. Virol. 2005; 32 (20: 162 - 165De Feo TM, Poli F, Mozi F et al. Risk of transmission of hepatitis B virus from anti-UBC positive cadaveric organ donors a collaborative study. Transplant. Proc. 2005; 37 (2): 1238 -1239De Feo TM, Poli F, Mozi F et al. Risk of transmission of hepatitis B virus from anti-UBC positive cadaveric organ donors a collaborative study. Transplant. Proc. 2005; 37 (2): 1238 -1239Костинов МП «ред». Вакцинация детей с нарушенным состоянием здоровья: Практическое руководство для врачей Изд. 4, М.: 4Мпресс, 2013; 432 ^Kostinov MP «ed» Vaktsinatsiya detey s narushennym sostoyaniem zdorov'ya: Prakticheskoe rukovodstvo dlya vrachey. Izd. 4, M.: 4Mpress, 2013; 432 s]Костинов МП «ред». Вакцинация детей с нарушенным состоянием здоровья: Практическое руководство для врачей Изд. 4, М.: 4Мпресс, 2013; 432 ^Kostinov MP «ed» Vaktsinatsiya detey s narushennym sostoyaniem zdorov'ya: Prakticheskoe rukovodstvo dlya vrachey. Izd. 4, M.: 4Mpress, 2013; 432 s]Ghio L, Pedrazzi C, Assael BM et al. Diphtheria and tetanus vaccine in pediatric patients with end -stage renal disease. Pediatr. Nephrol. 1996; 10 (4): 134Ghio L, Pedrazzi C, Assael BM et al. Diphtheria and tetanus vaccine in pediatric patients with end -stage renal disease. Pediatr. Nephrol. 1996; 10 (4): 134Dinits-Pensy M, Forrest GN, Cross AS, Hise MK The use of vaccines in adult patients with renal disease. Amer. J. of Kidney Dis. 2005; 46 (6): 997 - 1011Dinits-Pensy M, Forrest GN, Cross AS, Hise MK The use of vaccines in adult patients with renal disease. Amer. J. of Kidney Dis. 2005; 46 (6): 997 - 1011Pozetto B, Genin G, Gaudin OG et al. Live poliovirus vaccine in patients with chronic glomerulonephritis: effects on renal function and specific antibody response. Gin. Nephrol. 1987; 28 (4): 194 - 198Pozetto B, Genin G, Gaudin OG et al. Live poliovirus vaccine in patients with chronic glomerulonephritis: effects on renal function and specific antibody response. Gin. Nephrol. 1987; 28 (4): 194 - 198Furth SL, Hogg RJ, Tarver J et al. Varicella vaccination in children with chronic renal failure. A report of the Southwest pediatric Nephrology Study group. Pediatr. Nephrol. 2003; 18 (1): 33 - 38Furth SL, Hogg RJ, Tarver J et al. Varicella vaccination in children with chronic renal failure. A report of the Southwest pediatric Nephrology Study group. Pediatr. Nephrol. 2003; 18 (1): 33 - 38Sever M, Yidza A, Eraksoyb H et al. Immune response to Haemophilus influenzae type b vaccinaton in Renal transplant recipients with well - functioninig allografts. Nephron. 1999; 81: 55 - 59Sever M, Yidza A, Eraksoyb H et al. Immune response to Haemophilus influenzae type b vaccinaton in Renal transplant recipients with well - functioninig allografts. Nephron. 1999; 81: 55 - 59Laube GF, Berger C, Goetschel P et al. Immunization in children with chronic renal feilure. Pediatr. Nephrol. 2002; 17 (8): 638 - 642Laube GF, Berger C, Goetschel P et al. Immunization in children with chronic renal feilure. Pediatr. Nephrol. 2002; 17 (8): 638 - 642Antonen JA, Hannula PM, Pyhala R et al. Adequate seroresponse to influenza vaccination in dialysis patients. Nephron. 2000; 86: 56 - 61Antonen JA, Hannula PM, Pyhala R et al. Adequate seroresponse to influenza vaccination in dialysis patients. Nephron. 2000; 86: 56 - 61Antonen JA, Pyhala R, Hannulal PM et al. Influenza vaccination of dialysis patients: cross - reactivity of induced haemagglutination - inhibiting antibodies to H3N2 subtype antigenic variants is comparable with the response of naturally infected young healthy adults. Nephrol. Dial. Transplant. 2003; 18: 777 - 781Antonen JA, Pyhala R, Hannulal PM et al. Influenza vaccination of dialysis patients: cross - reactivity of induced haemagglutination - inhibiting antibodies to H3N2 subtype antigenic variants is comparable with the response of naturally infected young healthy adults. Nephrol. Dial. Transplant. 2003; 18: 777 - 781Brydak LB, Roszkowska-Blaim M, Machala M et al. Immunological response to influenza vaccination in children with renal failure. Nephrol. Dial. Tranplant. 2001; 16: 643 - 644Brydak LB, Roszkowska-Blaim M, Machala M et al. Immunological response to influenza vaccination in children with renal failure. Nephrol. Dial. Tranplant. 2001; 16: 643 - 644Kausz A, Pahari D. The value of vaccination in chronic kidney disease. Semin Dial. 2004; 17 (1): 9 -11.Kausz A, Pahari D. The value of vaccination in chronic kidney disease. Semin Dial. 2004; 17 (1): 9 -11.Pabico RC,Douglas RG, Betts RF et al. Antibody response to influentza vaccination in renal transplant patients: correlation with allograf function. Annals of Internal Med. 1976;85(4):431-436Pabico RC,Douglas RG, Betts RF et al. Antibody response to influentza vaccination in renal transplant patients: correlation with allograf function. Annals of Internal Med. 1976;85(4):431-436Tanzi E, Amendola A, Pariani E et al. Lack of effect of a booster dose of influenza vaccine in hemodialysis patients. J. Med. Virol. 2007; 79 (8): 1176 - 1179Tanzi E, Amendola A, Pariani E et al. Lack of effect of a booster dose of influenza vaccine in hemodialysis patients. J. Med. Virol. 2007; 79 (8): 1176 - 1179Квасова МА. Формирование иммунного ответа против пневмококковой инфекции и оценка клинического эффекта применения вакцин «Пневмо 23» и «Гриппол» у детей, страдающих гломерулонефритом и хронической почечной недостаточностью: автореф. Дис. канд. мед. наук. Н. Новгород, 2006; 22 [Kvasova MA. Formirovanie immunnogo otveta protiv pnevmokokkovoy infektsii i otsenka klinicheskogo effekta primeneniya vaktsin «Pnevmo 23» i «Grippol» u detey, stradayushchikh glomerulonefritom i khronicheskoy pochechnoy nedostatochnost’yu: avtoref. Dis. kand. med. nauk. N. Novgorod, 2006; 22]Квасова МА. Формирование иммунного ответа против пневмококковой инфекции и оценка клинического эффекта применения вакцин «Пневмо 23» и «Гриппол» у детей, страдающих гломерулонефритом и хронической почечной недостаточностью: автореф. Дис. канд. мед. наук. Н. Новгород, 2006; 22 [Kvasova MA. Formirovanie immunnogo otveta protiv pnevmokokkovoy infektsii i otsenka klinicheskogo effekta primeneniya vaktsin «Pnevmo 23» i «Grippol» u detey, stradayushchikh glomerulonefritom i khronicheskoy pochechnoy nedostatochnost’yu: avtoref. Dis. kand. med. nauk. N. Novgorod, 2006; 22]Петров РВ. Вакцина Гриппол: этапы разработки, испытания и внедрения. Сборник трудов 5-го Конгресса РААКИ «Современные проблемы аллергологии, иммунологии и иммунофармакологии». 2002; Т.1:134 - 180 [Petrov RV. Vaktsina Grippol: etapy razrabotki, ispytaniya i vnedreniya Sbornik trudov 5-ogo Kongressa RAAKI «Sovremennye problemy allergologii, immunologii i immunofarmakologii». 2002; 1: 134 - 180]Петров РВ. Вакцина Гриппол: этапы разработки, испытания и внедрения. Сборник трудов 5-го Конгресса РААКИ «Современные проблемы аллергологии, иммунологии и иммунофармакологии». 2002; Т.1:134 - 180 [Petrov RV. Vaktsina Grippol: etapy razrabotki, ispytaniya i vnedreniya Sbornik trudov 5-ogo Kongressa RAAKI «Sovremennye problemy allergologii, immunologii i immunofarmakologii». 2002; 1: 134 - 180]Schwarz A, Perez-Canto A Nephrotoxiticy of antiinfective drugs. Int. J. Clin.Pharmacol.Ther. 1998;36(3):164-167Schwarz A, Perez-Canto A Nephrotoxiticy of antiinfective drugs. Int. J. Clin.Pharmacol.Ther. 1998;36(3):164-167Neu AM, Lederman HM, Waraby BA et al. Haemophilus influenzae type b immunization in infants on peritoneal dialysis. Pediatric Peritoneal Dialysis Study Consortium. Pediatr. Nephrol. 1996; 10: 84 - 85Neu AM, Lederman HM, Waraby BA et al. Haemophilus influenzae type b immunization in infants on peritoneal dialysis. Pediatric Peritoneal Dialysis Study Consortium. Pediatr. Nephrol. 1996; 10: 84 - 85Neu AM, Fivush BA. Recommended immunization practices for pediatric renal transplant recipients. Pediatr. Transplant. 1998; 2 (4): 263 - 269Neu AM, Fivush BA. Recommended immunization practices for pediatric renal transplant recipients. Pediatr. Transplant. 1998; 2 (4): 263 - 269Furth SL, Arbus GS, Hogg R et al. Varicella vaccination in children with nephrotic syndrome: a report of the Southwest Pediatric Nephrology Study Group.J. Pediatr. 2003; 142 (2): 145 - 148Furth SL, Arbus GS, Hogg R et al. Varicella vaccination in children with nephrotic syndrome: a report of the Southwest Pediatric Nephrology Study Group.J. Pediatr. 2003; 142 (2): 145 - 148Furth SL, Neu AM, Sullivan EK et al. Immunization practices in children with renal disease: a report of the North American Pediatric Renal Transplant Cooperative Study. Pedatr. Nephrol. 1997; 11 (4): 443 - 446Furth SL, Neu AM, Sullivan EK et al. Immunization practices in children with renal disease: a report of the North American Pediatric Renal Transplant Cooperative Study. Pedatr. Nephrol. 1997; 11 (4): 443 - 446Rodgers DJ, Karp SK, Woodruff SD et al. Influenza immunization rates in the Intermountain End-Stage Renal Disease Network (Network 15) Adv. Ren.Replase Ther.2000;7(4 Suppl 1):581-584Rodgers DJ, Karp SK, Woodruff SD et al. Influenza immunization rates in the Intermountain End-Stage Renal Disease Network (Network 15) Adv. Ren.Replase Ther.2000;7(4 Suppl 1):581-584Gilbertson DT, Unruh M, McBean AM et al. Influenza vaccine delivery and effectiveness in end - stage renal disease. Kidney Int. 2003; 63: 738 - 743Gilbertson DT, Unruh M, McBean AM et al. Influenza vaccine delivery and effectiveness in end - stage renal disease. Kidney Int. 2003; 63: 738 - 743Mori K, Kawamura K, Honda M, Sasaki N. Responses in children to measles vaccination associated with perirenal transplantation. Pediatr. Int. 2009; 51 (5): 617-620Mori K, Kawamura K, Honda M, Sasaki N. Responses in children to measles vaccination associated with perirenal transplantation. Pediatr. Int. 2009; 51 (5): 617-620National Advisory Committee on Immunization: Statement on recommended use of pneumococcal conjugate vaccine. Canada Communicable Disease Report. 2002; 28: 1 - 20National Advisory Committee on Immunization: Statement on recommended use of pneumococcal conjugate vaccine. Canada Communicable Disease Report. 2002; 28: 1 - 20Kabakus N, Aydinoglu H, Bakkalogeu SA et al. Mumps intestitiae nephritis: a case report. Pediatr. Nephrol. 1999; 13 (9): 930 - 931Kabakus N, Aydinoglu H, Bakkalogeu SA et al. Mumps intestitiae nephritis: a case report. Pediatr. Nephrol. 1999; 13 (9): 930 - 931Возланов АФ, Майданник ВГ, Бидный ВГ, Багдасарова ИВ «ред». Основы нефрологии детского возраста. К.; Книга Плюс. 2000; 348 [Vozlanov AF, Maydannik VG, Bidnyy VG, Bagdasarova IV «ed». Osnovy nefrologiidetskogo vozrasta. K., Kniga Plyus. 2000: 348 ]Возланов АФ, Майданник ВГ, Бидный ВГ, Багдасарова ИВ «ред». Основы нефрологии детского возраста. К.; Книга Плюс. 2000; 348 [Vozlanov AF, Maydannik VG, Bidnyy VG, Bagdasarova IV «ed». Osnovy nefrologiidetskogo vozrasta. K., Kniga Plyus. 2000: 348 ]Linnemmann CCJr, First MR, Schiffman G Revaccination renal transplant and hemodialysis recipients with pneumococcal vaccine. Arch. Intern. Med. 1986; 146(8):1554-1556Linnemmann CCJr, First MR, Schiffman G Revaccination renal transplant and hemodialysis recipients with pneumococcal vaccine. Arch. Intern. Med. 1986; 146(8):1554-1556American Academy of Pediatrics, Committee on Infectious Diseases: Recommendations for the prevention of pneumococcal infections in infants and children: Use of 13 - valent pneumococcal conjugate vaccine (PCV 13) and pneumococcal polysaccharide vaccine (PPSV 23). Pediatrics. 2010: 126 (1): 186 - 190American Academy of Pediatrics, Committee on Infectious Diseases: Recommendations for the prevention of pneumococcal infections in infants and children: Use of 13 - valent pneumococcal conjugate vaccine (PCV 13) and pneumococcal polysaccharide vaccine (PPSV 23). Pediatrics. 2010: 126 (1): 186 - 190Hodson E. The management of idiopathic nephritic syndrome in children. Paediatr. Drugs. 2003; 5(5): 335 - 349Hodson E. The management of idiopathic nephritic syndrome in children. Paediatr. Drugs. 2003; 5(5): 335 - 349Schnape HW. Immunization practices in childhood nephritic syndrome: A survey of North American pediatric nephrologists. Pediatr. Nephrol. 1994; 8: 4 - 6Schnape HW. Immunization practices in childhood nephritic syndrome: A survey of North American pediatric nephrologists. Pediatr. Nephrol. 1994; 8: 4 - 6Tokars JJ, Frank M, Alter MJ et al. National surveillance of dialysis - associated diseases in the United States, 2000. Semin. Dial. 2002; 15 (3): 162 - 171Tokars JJ, Frank M, Alter MJ et al. National surveillance of dialysis - associated diseases in the United States, 2000. Semin. Dial. 2002; 15 (3): 162 - 171Wu HM, Tang JL, Sha ZH et al. Intervention for preventing infection nephritic syndrome. Cochrane Database Syst. Rev. 2004; (2) CD 003964Wu HM, Tang JL, Sha ZH et al. Intervention for preventing infection nephritic syndrome. Cochrane Database Syst. Rev. 2004; (2) CD 003964Butler JC, Breiman RF, Campbell JF et al. Pneumococcal polysacccharidesvaccine efficacy. An evaluation of current recommendation. JAMA.1993;270(15):1826-1831Butler JC, Breiman RF, Campbell JF et al. Pneumococcal polysacccharidesvaccine efficacy. An evaluation of current recommendation. JAMA.1993;270(15):1826-1831McInture P. Prevention of serious bacterial infection in children with nephritic syndrome. McInture P, Craig IC//J.Paediatr. Child.Health.1998;34(4):314-317McInture P. Prevention of serious bacterial infection in children with nephritic syndrome. McInture P, Craig IC//J.Paediatr. Child.Health.1998;34(4):314-317Arnold WC, Steele RW, Rastoge SP et al. Response to pneumococcal vaccine in renal allograft recipients. Am. J. Nephrol. 1985; 5 (1): 30-34Arnold WC, Steele RW, Rastoge SP et al. Response to pneumococcal vaccine in renal allograft recipients. Am. J. Nephrol. 1985; 5 (1): 30-34Nikoskelainen J, Koskela M, Forstrom J et al. Persistence of antibodies to pneumococcal vaccine in patients with chronic renal failure. Kidney Int.1985;28(4):672-677Nikoskelainen J, Koskela M, Forstrom J et al. Persistence of antibodies to pneumococcal vaccine in patients with chronic renal failure. Kidney Int.1985;28(4):672-677Wilkes JC, Nelson JD, Worhen HG et al. Response to pneumococcal vaccination in children with nephritic syndrome. Am.J.Kidney Dis.1982;2(1):43-46Wilkes JC, Nelson JD, Worhen HG et al. Response to pneumococcal vaccination in children with nephritic syndrome. Am.J.Kidney Dis.1982;2(1):43-46Pourfarziani V, Ramezani MB, Taheri S et al. Immunogenicity of pneumococcal vaccination in renal transplant recipients and hemodialysis patients: a comparative controlled trial. Ann. Transplant. 2008; 13 (3): 43 - 47Pourfarziani V, Ramezani MB, Taheri S et al. Immunogenicity of pneumococcal vaccination in renal transplant recipients and hemodialysis patients: a comparative controlled trial. Ann. Transplant. 2008; 13 (3): 43 - 47Ulinski T, Leroy S, Dubrel M et al. High serological response to pneumococcal vaccine in nephrotic children at disease onset on highdose prednisone. Pediatr. Nephrol. 2008; 23 (7): 1107-1113Ulinski T, Leroy S, Dubrel M et al. High serological response to pneumococcal vaccine in nephrotic children at disease onset on highdose prednisone. Pediatr. Nephrol. 2008; 23 (7): 1107-1113Giacchino R, Marcellini M, Timitilli A et al. Varicella vaccine in children requiring renal or hepatic transplantation. Transplantation. 1995; Nov 15; 60(9):1055-1056Giacchino R, Marcellini M, Timitilli A et al. Varicella vaccine in children requiring renal or hepatic transplantation. Transplantation. 1995; Nov 15; 60(9):1055-1056Sagar S, Pirofski L. Pneumococcal vaccinewith unknown vaccination status. Semin. Dial. 2000; 13: 207 - 208Sagar S, Pirofski L. Pneumococcal vaccinewith unknown vaccination status. Semin. Dial. 2000; 13: 207 - 208Dowell SF, Bresse JS Severe varicella associated with steroid use. Pediatrics. 1993; 92: 223-228Dowell SF, Bresse JS Severe varicella associated with steroid use. Pediatrics. 1993; 92: 223-228Webb NJA, Fitzpatrick MM, Hughes DA et al. Immunization against varicella in end stage and pre-end stage renal failure. Arch. Dis. Child. 2000; 82; 141 - 143Webb NJA, Fitzpatrick MM, Hughes DA et al. Immunization against varicella in end stage and pre-end stage renal failure. Arch. Dis. Child. 2000; 82; 141 - 143Lynfield R, Herrin JT, Rubin RH. Varicella in pediatric renal transplant recipients. Pediatrics. 1992; 90 (2 Pt 1): 216 - 220Lynfield R, Herrin JT, Rubin RH. Varicella in pediatric renal transplant recipients. Pediatrics. 1992; 90 (2 Pt 1): 216 - 220Olson AD, Shope TC, Flynn JT. Pretransplant varicella vaccination is cost-effective in pediatric renal transplantation. Pediatr. Transplant. 2001; 5 (1): 44 -50Olson AD, Shope TC, Flynn JT. Pretransplant varicella vaccination is cost-effective in pediatric renal transplantation. Pediatr. Transplant. 2001; 5 (1): 44 -50Broyer M, Tete MJ, Guest G et al. Varizella and zoster in children after kidney transplantation : long-term results of vaccination. Pediatrics. 1997; 99 (1): 35 - 39Broyer M, Tete MJ, Guest G et al. Varizella and zoster in children after kidney transplantation : long-term results of vaccination. Pediatrics. 1997; 99 (1): 35 - 39Janus N, Vacher L-V, Karie S et al. Vaccination and chronic kidney disease. Nephrol. Dial. Transplant 2008; 23: 800-807Janus N, Vacher L-V, Karie S et al. Vaccination and chronic kidney disease. Nephrol. Dial. Transplant 2008; 23: 800-807Katsushima N, Yazaki N, Sakamoto M. Effect and follow-up study on varicella vaccine. Biken - J. 1984; 27 (2-3): 51 - 58Katsushima N, Yazaki N, Sakamoto M. Effect and follow-up study on varicella vaccine. Biken - J. 1984; 27 (2-3): 51 - 58Fadrowski JJ, Furth SL. Varicella zoster virus: vaccination and implications in children with renal failure. Expert Rev. Vaccines. 2004; 3 (3): 291-298Fadrowski JJ, Furth SL. Varicella zoster virus: vaccination and implications in children with renal failure. Expert Rev. Vaccines. 2004; 3 (3): 291-298Chaves Tdo S, Lopes MH, de Souza VA et al. Seroprevalence of antibodies against varicella- zoster virus and response to the varicella vacine in pediatric renal transplant patients. Pediatr. Transplant. 2005; 9 (2): 192 -195Chaves Tdo S, Lopes MH, de Souza VA et al. Seroprevalence of antibodies against varicella- zoster virus and response to the varicella vacine in pediatric renal transplant patients. Pediatr. Transplant. 2005; 9 (2): 192 -195Zamora I, Simon JM, Da Silva ME, Piqueras AI. Attenuated varicella virus vaccine in children with renal transplants. Pediatr. Nephrol. 1994; 8 (2): 190-192Zamora I, Simon JM, Da Silva ME, Piqueras AI. Attenuated varicella virus vaccine in children with renal transplants. Pediatr. Nephrol. 1994; 8 (2): 190-192Rangel MC, Coronado VG, Fuler GL, Strikas RA. Vaccine recommendations for patients on chronic dialysis. The Advisory Committee on Immunization Practices and the American Academy of Pediatrics. Semin. Dial. 2000; 13 (2): 101 - 107Rangel MC, Coronado VG, Fuler GL, Strikas RA. Vaccine recommendations for patients on chronic dialysis. The Advisory Committee on Immunization Practices and the American Academy of Pediatrics. Semin. Dial. 2000; 13 (2): 101 - 107Fleishmann EH, Kruppenbacher J, Bock HL., Weber M. Active immunization against hepatitis A in dialysis patients. Nephrol. Dial. Transplant. 2002; 17: 1825 - 1828Fleishmann EH, Kruppenbacher J, Bock HL., Weber M. Active immunization against hepatitis A in dialysis patients. Nephrol. Dial. Transplant. 2002; 17: 1825 - 1828Abeyagunawardena AS, Goldblatt D, Andrews N, Trompeter RS. Risk of relapse after meningococcal C conjugate vaccine in nephritic syndrome. Lancet. 2003; 362 (9382): 449-450Abeyagunawardena AS, Goldblatt D, Andrews N, Trompeter RS. Risk of relapse after meningococcal C conjugate vaccine in nephritic syndrome. Lancet. 2003; 362 (9382): 449-450Taylor B, Andrews N, Stone J et al. No increased risk of relapse after meningococcal C conjugate vaccine in nephritic syndrome. Arch. Dis. Child. 2007; 92 (10): 887-889Taylor B, Andrews N, Stone J et al. No increased risk of relapse after meningococcal C conjugate vaccine in nephritic syndrome. Arch. Dis. Child. 2007; 92 (10): 887-889

The authors declare that there are no conflicts of interest present.