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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nefr</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology (Saint-Petersburg)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-6274</issn><issn pub-type="epub">2541-9439</issn><publisher><publisher-name>Pavlov First Saint-Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/1561-6274-2019-23-4-59-64</article-id><article-id custom-type="elpub" pub-id-type="custom">nefr-1722</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ. КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES. CLINICAL INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>Влияние нутриционного статуса на прогноз пациентов, получающих лечение гемодиализом</article-title><trans-title-group xml:lang="en"><trans-title>The influence of nutritional status on the prognosis of patients receiving treatment with hemodialysis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2116-4704</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крутько</surname><given-names>Д. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Krutko</surname><given-names>D. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Крутько Денис Михайлович - аспирант.</p><p>199034, Санкт-Петербург, Университетская набережная, д. 7-9, Тел.: +7-952-378-44-28</p></bio><bio xml:lang="en"><p>Denis M. Krutko – MD, Postgraduate student.</p><p>199034, St-Petersburg, Univer-sitetskaya emb. 7-9, Phone: +79523784428</p></bio><email xlink:type="simple">dr.denis.krutko@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1915-2237</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мазуренко</surname><given-names>С. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Mazurenko</surname><given-names>S. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мазуренко Сергей Олегович – профессор.</p><p>199034, Санкт-Петербург, Университетская набережная, д. 7-9, Тел.: +7-911-794-28-45</p></bio><bio xml:lang="en"><p>Sergei O. Mazurenko - MD, PhD, DMedSci.</p><p>199034, St-Petersburg, Univer-sitetskaya emb. 7-9, Phone: +79117942845</p></bio><email xlink:type="simple">dr_mazurenko@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3956-1628</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Старосельский</surname><given-names>К. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Staroselsky</surname><given-names>K. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Старосельский Константин Георгиевич.</p><p>196247, Санкт-Петербург, ул. Костюшко д. 2, Тел.: +7-905284-63-01</p></bio><bio xml:lang="en"><p>Konstantin G. Staroselsky – MD.</p><p>196247, Saint Petersbur, ul. Kostushko 2, Phone: +79052846301</p></bio><email xlink:type="simple">kng2002@inbox.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5040-6768</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ермолаева</surname><given-names>Л. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Ermolaeva</surname><given-names>L. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ермолаева Лариса Геннадьевна – доцент.</p><p>199034, Санкт-Петербург, Университетская набережная, д. 7-9, Тел.: +7-952-357-19-35</p></bio><bio xml:lang="en"><p>Larisa G. Ermolaeva - MD, PhD, Associate professor.</p><p>199034, St-Petersburg, Univer-sitetskaya emb. 7-9, Phone: +79523571935</p></bio><email xlink:type="simple">larerm@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Санкт-Петербургский государственный университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint-Petersburg State University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Городская больница № 26</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Hospital №26</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>23</day><month>06</month><year>2019</year></pub-date><volume>23</volume><issue>4</issue><fpage>59</fpage><lpage>64</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Крутько Д.М., Мазуренко С.О., Старосельский К.Г., Ермолаева Л.Г., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Крутько Д.М., Мазуренко С.О., Старосельский К.Г., Ермолаева Л.Г.</copyright-holder><copyright-holder xml:lang="en">Krutko D.M., Mazurenko S.O., Staroselsky K.G., Ermolaeva L.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephrolog.ru/jour/article/view/1722">https://journal.nephrolog.ru/jour/article/view/1722</self-uri><abstract><sec><title>Цель</title><p>Цель. Оценить влияние продолжительности терапии гемодиализом на состав тела пациентов с хронической болезнью почек 5 стадии. Изучить кумулятивную выживаемость пациентов, получающих хроническую терапию гемодиализом в зависимости от изменения их состава тела и нутриционного статуса.</p></sec><sec><title>Пациенты и методы</title><p>Пациенты и методы. 84 пациента с хронической болезнью почек 5 стадии, получавшие лечение в диализном центре Санкт-Петербургской городской больницы № 26 наблюдались в течение 2 лет. Для оценки состава тела и нутриционного статуса использовался аппарат «Диамант-АИСТ».</p></sec><sec><title>Результаты</title><p>Результаты. Были выявлены отрицательные корреляции между продолжительностью терапии гемодиализом и оцененными при помощи биоэлектрического импеданса параметрами: с общим объемом жидкости (r=-0,6, p&lt;0,05), безжировой массой (r=-0,558, p&lt;0,05), объемом свободной воды (r=-0,588, p&lt;0,05), жировой массой (r=-0,458, p&lt;0,05), тощей массой тела (r=-0,564, p&lt;0,05), активной клеточной массой (r=-0,5, p&lt;0,05). Также была выявлена статистически значимая разница между кумулятивной выживаемостью пациентов с высокой и низкой жировыми массами тела, умершими в результате кардиоваскулярных событий и в контексте общей смертности.</p></sec><sec><title>Заключение</title><p>Заключение. Наше исследование продемонстрировало, что изменения в объемах различных компартментов ассоциировано с продолжительностью получения терапии гемодиализом. Также выявлена статистически значимая разница в выживаемости пациентов с высокими и низкими значениями жировой массы тела.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. To assess the effect of duration of hemodialysis therapy on the body composition of patients with chronic kidney disease stage 5. To study the cumulative survival of patients receiving chronic hemodialysis therapy, depending on changes in their body composition and nutritional status.</p></sec><sec><title>Patients and methods</title><p>Patients and methods. 84 patients with terminal kidney disease from one hemodialysis center were observed for two years. Diamant-AIST device was used for the evaluation of the compartments' volumes and nutritional status.</p></sec><sec><title>Results</title><p>Results. Negative correlations between the time on the hemodialysis treatment and studied bioelectrical impedance analysis parameters were observed: correlation with total fluid volume (r=-0,6, p&lt;0,05), fat free mass (r=-0,558, p&lt;0,05), free water volume (r=-0,588, p&lt;0,05), fat mass (r=-0,458, p&lt;0,05), lean body mass (r=-0,564, p&lt;0,05), active cell mass (r=-0,5, p&lt;0,05). There was a statistically significant difference between the cumulative survival with regard to mortality from all causes and cardiovascular events of the patients with high and low values of the fat body mass.</p></sec><sec><title>Conclusions</title><p>Conclusions. Our study showed that change in the compartment's volumes is associated with the length of hemodialysis treatment. There is a statistically significant difference in survival of patients with low and high free fat mass.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>выживаемость</kwd><kwd>гемодиализ</kwd><kwd>терминальная почечная недостаточность</kwd><kwd>состав тела</kwd><kwd>нутриционный статус</kwd></kwd-group><kwd-group xml:lang="en"><kwd>survival</kwd><kwd>hemodialysis</kwd><kwd>terminal kidney disease</kwd><kwd>body composition</kwd><kwd>nutritional status</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Couser WG, Remuzzi G, Mendis S et al. The contribution of chronic kidney disease to the global burden of major noncommunicable diseases. KidneyInt 2011;80:1258-1270. doi: 10.1038/ki.2011.368</mixed-citation><mixed-citation xml:lang="en">Couser WG, Remuzzi G, Mendis S et al. 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