nefrНефрологияNephrology (Saint-Petersburg)1561-62742541-9439Pavlov First Saint-Petersburg State Medical Universitynefr-175Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESИнсулинорезистентность и нефропатия при ожирении у детейInsulin resistance and nephropathy in obese childrenСмирноваНаталия НиколаевнаSmirnovaNatalia Nnephro-uro-kids@mail.ruКуприенкоНаталья БорисовнаKuprienkoNatalja B.n-b-k@bk.ruПервый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова; Северо-Западный Федеральный медицинский исследовательский центр им. В.А. АлмазоваРоссияFirst Pavlov Saint-Petersburg State Medical University; Federal Almazov North-West Medical Research CentreRussian Federation2016010520162032834Copyright © Смирнова Н.Н., Куприенко Н.Б., 20162016Смирнова Н.Н., Куприенко Н.Б.Smirnova N.N., Kuprienko N.B.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.nephrolog.ru/jour/article/view/175

В обзоре приводятся сведения о механизмах развития инсулинорезистентности (ИР) при избыточном накоплении жировой ткани и влиянии нарушений углеводного и жирового обмена на функцию почек. Представлены данные о причинах возникновения ожирения и ИР на ранних этапах онтогенеза. Подчеркнута значимость ранней диагностики ИР и её коррекции при приобретенных болезнях почек у детей.

Current review provides a multifaceted analysis of development of insulin resistance in extra accumulation of lipids and renal function in carbohydrate and lipid metabolism disturbances. Causes of obesity and insulin resistance in early ontogenesis elucidated. Significance of early diagnosis of insulin resistance and its correction in acquired kidney diseases in children emphasized.

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The authors declare that there are no conflicts of interest present.