nefrНефрологияNephrology (Saint-Petersburg)1561-62742541-9439Pavlov First Saint-Petersburg State Medical University10.36485/1561-6274-2020-24-2-60-71nefr-1801Research ArticleНАБЛЮДЕНИЯ ИЗ ПРАКТИКИPRACTICAL NOTESДетергентные свойства как основа лечебного эффекта димексида при АА-амилоидозе инфекционной природы (клинический разбор)Detergent properties as the basis of the dimexide therapeutic effect in AA-amyloidosis infectious nature (clinical case analysis)https://orcid.org/0000-0003-4260-0226РамеевВ. В.RameevV.

Доц. Рамеев Вилен Вилевич, канд. мед наук.

Кафедра внутренних, профессиональных болезней и ревматологии.

119435, Москва, ул. Россолимо, д. 11, стр. 5.Тел.: +7(499)248-53-33, 89104936138 

Associate Professor Vilen V. Rameev MD, PhD.

Department of Internal, Occupational Diseases and Rheumatology.

119435, Moscow, st. Rossolimo, 11, p. 5.Phones: +7 (499) 248-53-33, 89104936138 

vvrameev@mail.ruКозловскаяЛ. В.KozlovskayaL.

Проф. Козловская (Лысенко) Лидия Владимировна, д-р мед. наук.

Кафедра внутренних, профессиональных болезней и ревматологии.

119435, Москва, ул. Россолимо, д. 11, стр. 5.Тел.: +7(499)248-53-33

Prof. Lidiya V. Kozlovskaya (Lysenko), MD, PhD, DMedSci.

Department of Internal, Occupational Diseases and Rheumatology.

119435, Moscow, st. Rossolimo, 11, p. 5.Phones: +7 (499) 248-53-33

РамееваА. С.RameevaA.

Аспирант Рамеева Анна Сергеевна.

Кафедра внутренних, профессиональных болезней и ревматологии.

119435, Москва, ул. Россолимо, д. 11, стр. 5.Тел.: +7(499)248-53-33

Postgraduate student Anna S. Rameeva, MD.

Department of Internal, Occupational Diseases and Rheumatology.

119435, Moscow, st. Rossolimo, 11, p. 5.Phones: +7 (499) 248-53-33

ТаоП. П.TaoP.

Аспирант Тао Павел Полович.

Кафедра внутренних, профессиональных болезней и ревматологии.

119435, Москва, ул. Россолимо, д. 11, стр. 5.Тел.: +7(499)248-53-33

Postgraduate student Pavel P. Tao, MD.

Department of Internal, Occupational Diseases and Rheumatology.

119435, Moscow, st. Rossolimo, 11, p. 5.Phones: +7 (499) 248-53-33

Первый Московский государственный медицинский университет им. И.М.Сеченова (Сеченовский Университет)РоссияFirst Sechenov Moscow State Medical UniversityRussian Federation2020080220202426071Copyright © Рамеев В.В., Козловская Л.В., Рамеева А.С., Тао П.П., 20202020Рамеев В.В., Козловская Л.В., Рамеева А.С., Тао П.П.Rameev V., Kozlovskaya L., Rameeva A., Tao P.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.nephrolog.ru/jour/article/view/1801

В статье на примере клинического наблюдения обсуждаются современные возможности лечения постинфекционного АА-амилоидоза димексидом. Подробно обсуждается проблема функционального амилоида, дискутируются перспективы принципа резорбции амилоида в лечении системного амилоидоза. Приведена история применения димексида в медицинской практике, представлены необходимые данные по фармакологии димексида.

The article discusses the current possibilities of postinfectious AA-amyloidosis treatment with dimexide on the example of clinical observation, discribes in detail the problem of functional amyloid and debates the prospects of the principle of amyloid resorption in the treatment of systemic amyloidosis. The history of the use of dimexide in medical practice is given, thenecessary dataon the pharmacology of dimexide are presented.

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The authors declare that there are no conflicts of interest present.