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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nefr</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology (Saint-Petersburg)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-6274</issn><issn pub-type="epub">2541-9439</issn><publisher><publisher-name>Pavlov First Saint-Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">nefr-190</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Прогностическая значимость микроделеций локусов AZF и синдрома Клайнфельтера у мужчин с азооспермией в отношении результативности биопсии яичка и исходов вспомогательных репродуктивных технологий (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>The prognostic value of AZF loci microdeletion and Klinefelter’s syndrome in men with azoospermia in relation to the effectiveness of testis biopsy and outcomes of assisted reproductive technology (review of literature)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аль-Шукри</surname><given-names>Сальман Хасунович</given-names></name><name name-style="western" xml:lang="en"><surname>Al'-Shukri</surname><given-names>S. Kh.</given-names></name></name-alternatives><email xlink:type="simple">alshukri@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гзгзян</surname><given-names>Александр Мкртичевич</given-names></name><name name-style="western" xml:lang="en"><surname>Gzgzian</surname><given-names>A. M.</given-names></name></name-alternatives><email xlink:type="simple">agzgzyan@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Боровец</surname><given-names>Сергей Юрьевич</given-names></name><name name-style="western" xml:lang="en"><surname>Borovetc</surname><given-names>S. Y.</given-names></name></name-alternatives><email xlink:type="simple">sborovets@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белоусов</surname><given-names>Владислав Яковлевич</given-names></name><name name-style="western" xml:lang="en"><surname>Belousov</surname><given-names>V. Y.</given-names></name></name-alternatives><email xlink:type="simple">urolog.kaf@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Торопов</surname><given-names>Виктор Александрович</given-names></name><name name-style="western" xml:lang="en"><surname>Toropov</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">toropov-1990@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО ПСПбГМУ им. И.П. Павлова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pavlov First Saint-Petersburg State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБНУ НИИ акушерства, гинекологии и репродуктологии им. Д.О. Отта</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FSBI Research institute of obstetrics, gynecology and reproductology named after. D.O. Ott</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>НИИ хирургии и неотложной медицины ГБОУ ВПО ПСПбГМУ им. И.П. Павлова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pavlov First Saint-Petersburg State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>01</day><month>07</month><year>2016</year></pub-date><volume>20</volume><issue>4</issue><fpage>40</fpage><lpage>46</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Аль-Шукри С.Х., Гзгзян А.М., Боровец С.Ю., Белоусов В.Я., Торопов В.А., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Аль-Шукри С.Х., Гзгзян А.М., Боровец С.Ю., Белоусов В.Я., Торопов В.А.</copyright-holder><copyright-holder xml:lang="en">Al'-Shukri S.K., Gzgzian A.M., Borovetc S.Y., Belousov V.Y., Toropov V.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephrolog.ru/jour/article/view/190">https://journal.nephrolog.ru/jour/article/view/190</self-uri><abstract><p>В данной статье представлен обзор отечественной и зарубежной литературы о результативности процедур биопсии яичка и вспомогательных репродуктивных технологий у мужчин с азооспермией, обусловленной микроделецией локуса AZF длинного плеча Y хромосомы и синдромом Клайнфельтера.</p></abstract><trans-abstract xml:lang="en"><p>This article provides native and foreign literature review about effectiveness of testis biopsy and assisted reproductive technologies (ART) in men with azoospermia caused by microdeletion of Y-chromosome long arm AZF locus and Klinefelter’s syndrome.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>азооспермия</kwd><kwd>синдром Клайнфельтера</kwd><kwd>микроделеция AZF</kwd><kwd>ТЕSЕ</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ICSI</kwd><kwd>azoospermia</kwd><kwd>Klinefelter’s syndrome</kwd><kwd>microdeletion AZF</kwd><kwd>TESE</kwd><kwd>ICSI</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Черных ВБ, Курило ЛФ, Шилейко ЛВ и др. 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