nefrНефрологияNephrology (Saint-Petersburg)1561-62742541-9439Pavlov First Saint-Petersburg State Medical University10.36485/1561-6274-2020-24-6-78-84nefr-1904Research ArticleОРИГИНАЛЬНЫЕ СТАТЬИ. КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯORIGINAL ARTICLES. CLINICAL INVESTIGATIONSУровень артериального давления и прогрессирование патологии почек у детей с Х-сцепленным синдромом АльпортаBlood pressure level and progression of renal disease in children with Х-linked Alport syndromehttps://orcid.org/0000-0002-3699-1884АксеноваМ. Е.AksenovaM. E.

Аксенова Марина Евгеньевна, кан. мед наук, Отдел наследственных и приобретенных болезней почек

125412, Москва, ул. Талдомская, д. 2Тел.: +7(495)4832183 

Marina E. Aksenova, MD, PhD, Nephrology Department

125412, Moscow, Taldomskaya str. 2Phone: +7(495)4832183 

maksyonova@pedklin.ruhttps://orcid.org/0000-0003-3182-5892КоньковаН. Е.KonkovaN. E.

Конькова Наталья Евгеньевна, кан. мед наук, зав. отделением нефрологии

125412, Москва, ул. Талдомская, д. 2Тел.: +7(495)4832192 

Natalia E. Konkova, MD, PhD, Head of Nephrology Department

125412, Moscow, Taldomskaya str. 2Phone: +7(495)4832192 

nkonkova@pedklin.ruhttps://orcid.org/0000-0002-1821-6972ТутельманК. М.TutelmanK. M.

Тутельман Константин Моисеевич, кан. мед наук, врач-кардиолог отделения функциональной диагностики

125412, Москва, ул. Талдомская, д. 2Тел.: +7(495)4833105 

Konstantin M. Tutelman, cardiologist of the functional diagnostics department

125412, Moscow, Taldomskaya str. 2Phone: +7(495)4833105 

ktutelman@pedklin.ruНаучно-исследовательский клинический институт педиатрии имени академика Ю.Е. Вельтищева, Российский национальный исследовательский медицинский университет имени Н.И. ПироговаРоссияY. Veltischev Research and Clinical Institute for Pediatrics at N. Pirogov Russian National Research Medical UniversityRussian Federation2020251120202467884Copyright © Аксенова М.Е., Конькова Н.Е., Тутельман К.М., 20202020Аксенова М.Е., Конькова Н.Е., Тутельман К.М.Aksenova M.E., Konkova N.E., Tutelman K.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.nephrolog.ru/jour/article/view/1904детисиндром Альпорта Х-сцепленныйартериальное давлениемониторирование давления амбулаторноегипертензияпротеинурияскорость клубочковой фильтрациихроническая почечная недостаточностьchildrenAlport syndrome X-linkedblood pressureblood pressure monitoring ambulatoryblood hypertensionproteinuriaglomerular filtration ratechronic renal failureReferencesSesso HD, Stampfer MJ, Rosner B et al. Systolic and diastolic blood pressure, pulse pressure, and mean arterial pressure as predictors of cardiovascular disease risk in Men. Hypertension 2000(5):801-807. doi: 10.1161/01.hyp.36.5.801Sesso HD, Stampfer MJ, Rosner B et al. Systolic and diastolic blood pressure, pulse pressure, and mean arterial pressure as predictors of cardiovascular disease risk in Men. Hypertension 2000(5):801-807. doi: 10.1161/01.hyp.36.5.801Cui X, Zhao Q, Yu J et al. Cumulative mean arterial pressure and risks of adverse cardiac and cerebrovascular events: a prospective cohort study of 53,813 adults. J Hum Hypertens 2018(32):585-593. doi: 10.1038/s41371-018-0075-9Cui X, Zhao Q, Yu J et al. Cumulative mean arterial pressure and risks of adverse cardiac and cerebrovascular events: a prospective cohort study of 53,813 adults. J Hum Hypertens 2018(32):585-593. doi: 10.1038/s41371-018-0075-9Papaioannou TG, Protogerou AD, Vrachatis D et al. Mean arterial pressure values calculated using seven different methods and their associations with target organ deterioration in a singlecenter study of 1878 individuals. Hypertens Res 2016(9):640-647. doi: 10.1038/hr.2016.41Papaioannou TG, Protogerou AD, Vrachatis D et al. Mean arterial pressure values calculated using seven different methods and their associations with target organ deterioration in a singlecenter study of 1878 individuals. Hypertens Res 2016(9):640-647. doi: 10.1038/hr.2016.41Ku E, Glidden DV, Johansen KL et al. Association between strict blood pressure control during chronic kidney disease and lower mortality after onset of end-stage renal disease. Kidney Int 2015(87):1055-1060. doi: 10.1038/ki.2014.376Ku E, Glidden DV, Johansen KL et al. Association between strict blood pressure control during chronic kidney disease and lower mortality after onset of end-stage renal disease. Kidney Int 2015(87):1055-1060. doi: 10.1038/ki.2014.376Yang H, Guo X, Zhang X et al. The relationship between mean arterial pressure and decreased glomerular filtration rate in rural areas of Northeast China. BMC Nephrol 2015(16):137. doi: 10.1186/s12882-015-0115-4Yang H, Guo X, Zhang X et al. The relationship between mean arterial pressure and decreased glomerular filtration rate in rural areas of Northeast China. BMC Nephrol 2015(16):137. doi: 10.1186/s12882-015-0115-4Appel LJ, Wright JT, Greene T et al. Collaborative Research Group: Intensive blood pressure control in hypertensive chronic kidney disease. N Engl J Med 2010(363):918-929. doi: 10.1056/NEJMoa0910975Appel LJ, Wright JT, Greene T et al. Collaborative Research Group: Intensive blood pressure control in hypertensive chronic kidney disease. N Engl J Med 2010(363):918-929. doi: 10.1056/NEJMoa0910975ESCAPE Trial Group, Wühl E, Trivelli A et al. Strict blood pressure control and progression of renal failure in children. N Engl J Med 2009(361):1639-1650. doi: 10.1056/NEJMoa0902066ESCAPE Trial Group, Wühl E, Trivelli A et al. Strict blood pressure control and progression of renal failure in children. N Engl J Med 2009(361):1639-1650. doi: 10.1056/NEJMoa0902066Lurbe E, Agabiti-Rosei E, Cruickshank JK et al. 2016 European Society of Hypertension guidelines for the management of high blood pressure in children and adolescents. J Hypertens 2016(10):1887-1920. doi: 10.1097/HJH.0000000000001039Lurbe E, Agabiti-Rosei E, Cruickshank JK et al. 2016 European Society of Hypertension guidelines for the management of high blood pressure in children and adolescents. J Hypertens 2016(10):1887-1920. doi: 10.1097/HJH.0000000000001039KDIGO CLINICAL PRACTICE GUIDELINE ON THE MANAGEMENT OF BLOOD PRESSURE IN CHRONIC KIDNEY DISEASE. https://kdigo.org/wp-content/uploads/2016/10/KDIGO-BPManagement-GL-public-review-draft-8Feb2020.pdfKDIGO CLINICAL PRACTICE GUIDELINE ON THE MANAGEMENT OF BLOOD PRESSURE IN CHRONIC KIDNEY DISEASE. https://kdigo.org/wp-content/uploads/2016/10/KDIGO-BPManagement-GL-public-review-draft-8Feb2020.pdfFlynn JT, Kaelber DC, Baker-Smith CM et al. SUBCOMMITTEE ON SCREENING AND MANAGEMENT OF HIGH BLOOD PRESSURE IN CHILDREN. Clinical Practice Guideline for Screening and Management of High Blood Pressure in Children and Adolescents. Pediatrics 2017(3):pii:e20171904. doi: 10.1542/peds.2017-1904Flynn JT, Kaelber DC, Baker-Smith CM et al. SUBCOMMITTEE ON SCREENING AND MANAGEMENT OF HIGH BLOOD PRESSURE IN CHILDREN. Clinical Practice Guideline for Screening and Management of High Blood Pressure in Children and Adolescents. Pediatrics 2017(3):pii:e20171904. doi: 10.1542/peds.2017-1904Ardissino G, Vigao S, Testa S et al. No clear evidence of ACEi efficacy on the progression of chronic kidney disease in children with hypodysplastic nephropathy – Report from the ItalKid Project database. Nephrology Dialysis Transplantation 2007(9):2525-2530. doi: 10.1093/ndt/gfm237Ardissino G, Vigao S, Testa S et al. No clear evidence of ACEi efficacy on the progression of chronic kidney disease in children with hypodysplastic nephropathy – Report from the ItalKid Project database. Nephrology Dialysis Transplantation 2007(9):2525-2530. doi: 10.1093/ndt/gfm237Schrier RW, Abebe KZ, Perrone RD et al. Blood pressure in early autosomal dominant polycystic kidney disease. N Engl J Med 2014(24):2255-2266. doi: 10.1056/NEJMoa1402685Schrier RW, Abebe KZ, Perrone RD et al. Blood pressure in early autosomal dominant polycystic kidney disease. N Engl J Med 2014(24):2255-2266. doi: 10.1056/NEJMoa1402685Cadnapaphornchai MA, McFann K, Strain JD et al. Prospective change in renal volume and function in children with ADPKD. Clin J Am Soc Nephrol 2009(4):820-829. doi: 10.2215/CJN.02810608Cadnapaphornchai MA, McFann K, Strain JD et al. Prospective change in renal volume and function in children with ADPKD. 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Association of TimeVarying Blood Pressure With Chronic Kidney Disease Progression in Children. JAMA Netw Open 2020(2):e1921213. doi: 10.1001/jamanetworkopen.2019.21213Fathallah-Shaykh SA, Flynn JT, Pierce CB et al. Progression of pediatric CKD of nonglomerular origin in the CKiD cohort. Clin J Am Soc Nephrol 2015(4):571-577. doi: 10.2215/CJN.07480714Fathallah-Shaykh SA, Flynn JT, Pierce CB et al. Progression of pediatric CKD of nonglomerular origin in the CKiD cohort. Clin J Am Soc Nephrol 2015(4):571-577. doi: 10.2215/CJN.07480714Warady BA, Abraham AG, Schwartz GJ et al. Predictors of Rapid Progression of Glomerular and Nonglomerular Kidney Disease in Children and Adolescents: The Chronic Kidney Disease in Children (CKiD) Cohort. Am J Kidney Dis 2015(6):878-888. doi: 10.1053/j.ajkd.2015.01.008Warady BA, Abraham AG, Schwartz GJ et al. 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The authors declare that there are no conflicts of interest present.