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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nefr</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology (Saint-Petersburg)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-6274</issn><issn pub-type="epub">2541-9439</issn><publisher><publisher-name>Pavlov First Saint-Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">nefr-193</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Артериальная гипертензия и выживаемость у пациентов на гемодиализе</article-title><trans-title-group xml:lang="en"><trans-title>Arterial hypertension and survival in hemodialysis patients</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сабодаш</surname><given-names>Анастасия Борисовна</given-names></name><name name-style="western" xml:lang="en"><surname>Sabodash</surname><given-names>A. B.</given-names></name></name-alternatives><email xlink:type="simple">sabodash@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Казанцева</surname><given-names>Наталья Сергеевна</given-names></name><name name-style="western" xml:lang="en"><surname>Kazantseva</surname><given-names>N. S.</given-names></name></name-alternatives><email xlink:type="simple">nkazanceva7@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Земченков</surname><given-names>Александр Юрьевич</given-names></name><name name-style="western" xml:lang="en"><surname>Zemchenkov</surname><given-names>A. Y.</given-names></name></name-alternatives><email xlink:type="simple">kletk@inbox.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Салихова</surname><given-names>Карина Александровна</given-names></name><name name-style="western" xml:lang="en"><surname>Salikhova</surname><given-names>K. A.</given-names></name></name-alternatives><email xlink:type="simple">karisha13@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макарова</surname><given-names>Оксана Валерьевна</given-names></name><name name-style="western" xml:lang="en"><surname>Makarova</surname><given-names>O. V.</given-names></name></name-alternatives><email xlink:type="simple">boicova_oksana@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Земченков</surname><given-names>Геннадий Александрович</given-names></name><name name-style="western" xml:lang="en"><surname>Zemchenkov</surname><given-names>G. A.</given-names></name></name-alternatives><email xlink:type="simple">zga13@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Скатерникова</surname><given-names>Виктория Валерьевна</given-names></name><name name-style="western" xml:lang="en"><surname>Skaternikova</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">irsaskat@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Банишевская</surname><given-names>Анастасия Владимировна</given-names></name><name name-style="western" xml:lang="en"><surname>Banishevskaya</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">nastasya848@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый Санкт-Петербургский государственный медицинский университет им. И.П. Павлова; ББраун Авитум Руссланд Клиникс</institution><country>Россия</country></aff><aff xml:lang="en"><institution>First nephrology and dialysis Saint-Petersburg State medical university n.a. I.P Pavlov; BBraun Avitum Russland Clinics</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ББраун Авитум Руссланд Клиникс</institution><country>Россия</country></aff><aff xml:lang="en"><institution>BBraun Avitum Russland Clinics</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Первый Санкт-Петербургский государственный медицинский университет им. И.П. Павлова; Северо-Западный государственный медицинский университет им. И.И. Мечникова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>First nephrology and dialysis Saint-Petersburg State medical university n.a. I.P Pavlov; North-Western State medical university n.a. I.I.Mechnikov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>01</day><month>07</month><year>2016</year></pub-date><volume>20</volume><issue>4</issue><fpage>62</fpage><lpage>71</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сабодаш А.Б., Казанцева Н.С., Земченков А.Ю., Салихова К.А., Макарова О.В., Земченков Г.А., Скатерникова В.В., Банишевская А.В., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Сабодаш А.Б., Казанцева Н.С., Земченков А.Ю., Салихова К.А., Макарова О.В., Земченков Г.А., Скатерникова В.В., Банишевская А.В.</copyright-holder><copyright-holder xml:lang="en">Sabodash A.B., Kazantseva N.S., Zemchenkov A.Y., Salikhova K.A., Makarova O.V., Zemchenkov G.A., Skaternikova V.V., Banishevskaya A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephrolog.ru/jour/article/view/193">https://journal.nephrolog.ru/jour/article/view/193</self-uri><abstract><p>ЦЕЛЬ: определить уровень артериального давления (АД), измеряемого в разных временных точках «диализной» недели, для оценки отдаленного прогноза у гемодиализных пациентов. ПАЦИЕНТЫ И МЕТОДЫ: у 86 пациентов одного диализного центра в двухлетнем проспективном исследовании оценивали взаимосвязь уровня АД перед, в ходе, после сеанса диализа, в междиализный интервал и выживаемости пациентов. РЕЗУЛЬТАТЫ: АД у большинства пациентов, снижаясь в ходе диализа, продолжает уменьшаться в последующий междиализный день. АД перед первым сеансом составило 146±24 и 85±14, перед вторым - 141±19 и 82±13, перед третьим - 141±23 и 84±15 мм Hg, в целом соответствуя целевому (&lt;140 и 90 мм Hg) у 57% женщин и 48% мужчин. С междиализными прибавками массы тела (МТ) взаимосвязано только систолическое АД перед сеансом (r=0,222; p=0,04), тогда как диастолическое АД - в любой интервал, в большей степени - перед сеансом (r=0,454^0,281; p&lt;0,01). Двухлетняя выживаемость пациентов по Kaplan-Meier не зависела от преддиализного и интрадиализного АД; влияние последиализного АД приближалось к статистической значимости в скорректированной регрессионной модели Кокса (р=0,051). Междиализное систолическое АД выше 141 мм Hg (граница верхнего и среднего тертиля) было взаимосвязано с относительным риском (ОР) летальности 3,23 (95%ДИ 1,08÷9,66); р=0,036. В регрессионную модель также вошли прибавка массы тела (ОР=1,73 каждый % прибавки МТ), возраст (ОР +7% за 1 год) и пол. Диастолическое АД выше 84 ммHg в междиализный период ассоциировалось с увеличением риска смерти: ОР=6,84 (95%ДИ 1,55^30,2), р=0,011. ЗАКЛЮЧЕНИЕ: АД в междиализные дни в большей степени, чем на диализе, влияет на выживаемость.</p></abstract><trans-abstract xml:lang="en"><p>THE AIM: to evaluate blood pressure (BP) level importance measured in different phases of “dialysis” week as a prognostic factor in hemodialysis patients. PATIENTS AND METHOD: correlation between BP level before, during and after dialysis in in-terdialytic interval and survival of patients was estimated in two years prospective study of one dialysis center. RESULTS: BP in most of patients decreases during dialysis session and continues to decrease in interdialysis interval. BP before first session was 146±24 and 85±14, second - 141±19 and 82±13, third - 141±23 and 84±15 mm Hg, being in target range (&lt;140/90 mm Hg) in 57% of women and 48% of men. The interdialysis body mass gain (BM) was linked only with systolic BP measured before session (r=0.222; p=0.04), and diastolic BP measured at any time point, more closely - with predialysis values (r=0.454÷0.281; p&lt;0.01). Two year survival (Kaplan-Meier) was not associated with predialysis and intradialysis BP; the association with postdialysis BP was close to significance in adjusted Cox regression model (p=0.051). Interdialysis BP higher 141 mm Hg (border of upper and middle tercile) was interrelated with mortality relative risk (RR) 3.23 (95%CI 1.08÷9.66); p=0.036. Regression model also included BM gain (RR=1.73 per 1% IWG), age (RR +7% per 1 year) and gender. Diastolic BP higher than 84 mm HG in interdialysis period was associated with increase of mortality level: RR=6.84 (95%CI 1.55÷30.2) p=0.011. CONCLUSION: BP in interdialysis period is significantly more important for survival than on dialysis.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гемодиализ</kwd><kwd>артериальная гипертензия</kwd><kwd>гипергидратация</kwd><kwd>выживаемость</kwd></kwd-group><kwd-group xml:lang="en"><kwd>«домашнее» артериальное давление</kwd><kwd>hemodialysis</kwd><kwd>arterial hypertension</kwd><kwd>«home» blood pressure</kwd><kwd>hyperhydration</kwd><kwd>survival</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ермоленко ВМ, Филатова НН. О целевых значениях артериального давления у больных ХБП (обзор литературы). Нефрология и диализ 2010; 12(4): 238-241 [Ermolenko VM, Filatova NN. On the target blood pressure in patients with CKD; Review. 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