nefrНефрологияNephrology (Saint-Petersburg)1561-62742541-9439Pavlov First Saint-Petersburg State Medical University10.36485/1561-6274-2024-28-2-37-42TJBTMInefr-2314Research ArticleОРИГИНАЛЬНЫЕ СТАТЬИ. КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯORIGINAL ARTICLES. CLINICAL INVESTIGATIONSОстрое повреждение почек легкой и средней степени тяжести у больных COVID-19Acute kidney injury of mild to moderate severity in patients with COVID-19https://orcid.org/0009-0002-2567-125XГоловинаЕ. Н.GolovinaE. N.

Аспирант Головина Елена Николаевна

129110, Москва, ул. Щепкина, д. 61/2

Postgraduate student Golovina Elena Nikolaevna, MD

129110, Moscow, st.Shchepkina, 61/2

Elena_Golovina81@mail.ruhttps://orcid.org/0000-0001-8497-0693ВатазинА. В.VatasinA. V.

Проф. Ватазин Андрей Влади мирович, д-р мед. наук

129110, Москва, ул. Щепкина, д. 61/2

Prof. Vatasin Andrey Vladimirovich, MD, PhD, DMed Sci

129110, Moscow, st.Shchepkina, 61/2

Vatasin@yandex.ruКафедра трансплантологии, нефрологии и искусственных органов, Московский областной научно-исследовательский клинический институт им. М.Ф. ВладимирскогоРоссияDepartment of transplantology, nephrology and artificial organs, Moscow Regional Research Clinical Institute name after M.F.VladimirskyRussian Federation2024120720242823742Copyright © Головина Е.Н., Ватазин А.В., 20242024Головина Е.Н., Ватазин А.В.Golovina E.N., Vatasin A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.nephrolog.ru/jour/article/view/2314ЦЕЛЬ

ЦЕЛЬ: изучить частоту острого повреждения почек легкой и средней степени тяжести у больных COVID-19.

ПАЦИЕНТЫ И МЕТОДЫ

ПАЦИЕНТЫ И МЕТОДЫ. Проанализированы данные историй болезни 200 больных, госпитализированных в инфекционное отделение Наро-Фоминской областной больницы Московской области по поводу COVID-19 преимущественно с легкой и средней степенью тяжести поражения легких по данным компьютерной томографии, не требующих респираторной поддержки и заместительной почечной терапии.

РЕЗУЛЬТАТЫ

РЕЗУЛЬТАТЫ. Несмотря на то, что у анализируемой группы больных было не самое тяжелое течение COVID-19, первая стадия острого повреждения почек  выявлена у 22,5% больных, что проявлялось временным снижением почасового диуреза, повышением уровня креатинина, мочевины, протеинурией и эритроцитурией.

ЗАКЛЮЧЕНИЕ

ЗАКЛЮЧЕНИЕ. Развитие острого повреждения почек чаще всего ассоциировалось с пожилым возрастом, наличием ишемической болезни сердца, артериальной гипертензией, сахарным диабетом и ожирением.

THE AIM

THE AIM: to study the incidence of mild to moderate acute kidney injury in patients with COVID-19.

PATIENTS AND METHODS

PATIENTS AND METHODS. The data of the case histories of 200 patients hospitalized in the infectious diseases department of the Naro-Fominsk Regional Hospital of the Moscow region for COVID-19 were analyzed, mainly with mild to moderate severity of lung damage according to computed tomography, which do not require respiratory support and renal replacement therapy.

RESULTS

RESULTS. Despite the fact that the analyzed group of patients did not have the most severe course of COVID-19, the first stage of acute kidney injury was detected in 22.5% of patients, which was manifested by a temporary decrease in hourly diuresis, increased creatinine, urea, proteinuria and erythrocyturia.

CONCLUSION

CONCLUSION. The development of acute kidney injury was most often associated with older age, coronary heart disease, arterial hypertension, diabetes mellitus and obesity.

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The authors declare that there are no conflicts of interest present.