nefrНефрологияNephrology (Saint-Petersburg)1561-62742541-9439Pavlov First Saint-Petersburg State Medical University10.36485/1561-6274-2025-29-2-17-26IAFPLTnefr-2415Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESБиомаркеры раннего выявления поражения сердца и сосудов у детей с хронической болезнью почекBiomarkers of early detection of heart and vascular damage in children with chronic kidney diseasehttps://orcid.org/0000-0002-9356-4870КаримджановИ. А.KarimdzhanovI. A.

Проф. Каримджанов Илхамджан Асамович - д-р мед. наук Ташкентская медицинская академия, кафедра детских болезней №2.

100102, Ташкент, ул. Фароби, д. 2. Тел. (+998) 903515346

Prof. Ilhamdzhan A. Karimdzhanov, MD, PhD, DMedSci Tashkent Medical Academy, Department of Children's Diseases №2.

100102, Uzbekistan, Tashkent, Farobi St., 2, Phone: (+998) 903515346

dr.ilhomjon@mail.ruhttps://orcid.org/0000-0003-3577-499XИскановаГ. Х.IskanovaG. Kh.

Доц. Исканова Гулшан Холдоровна - канд. мед. наук. Ташкентская медицинская академия, кафедра детских болезней №2.

100102, Ташкент, ул. Фароби, д. 2. Тел. (+998) 903706440

Associate professor Gulshan Kh.Iskanova - MD, PhD Tashkent Medical Academy, Department of Children's Diseases №2.

100102, Uzbekistan, Tashkent, Farobi St., 2, Phone: (+998) 903706440

gulshan1972iskanova@gmail.comhttps://orcid.org/0009-0002-5969-082XМадаминоваМ. Ш.MadaminovaM. Sh.

Ассистент Мадаминова Малика Шавкатовна - PhD. Ташкентская медицинская академия, кафедра детских болезней №2.

100102, Ташкент, ул. Фароби, д. 2., Тел. (+998) 90 1757180

Assistant Malika Sh. Маdaminova - MD, PhD. Tashkent Medical Academy, Department of Children's Diseases №2

100102, Uzbekistan, Tashkent, Farobi St., 2, Phone: (+998) 914261501

m.malika1992@mail.ruhttps://orcid.org/0009-0000-6943-1624ГазиеваА. С.GazievaA. S.

Ассистент Газиева Азиза Сафаровна - Ташкентская медицинская академия, кафедра детских болезней №2.

100102, Ташкент, ул. Фароби, д. 2, Тел. (+998) 90 9612294

Assistant Aziza S. Gazieva - Tashkent Medical Academy, Department of Children's Diseases №2.

100102, Uzbekistan, Tashkent, Farobi St., 2, Phone: (+998) 90 9612294

dr.azizaxon.safarovna@mail.ruhttps://orcid.org/0000-0001-8297-296XТогаевМ. К.TogaevM. K.

Ассистент Тогаев Мухиддин Курбонмуродович - Ташкентская медицинская академия, кафедра детских болезней №2.

100102, Ташкент, ул. Фароби, д. 2, Тел. (+998) 99 0157555

Assistant Muhiddin K. Togaev - Tashkent Medical Academy, Department of Children's Diseases №2.

100102, Uzbekistan, Tashkent, Farobi St., 2, Phone: (+998) 99 0157555

dr.togaevmuhiddin1129@bk.ruТашкентская медицинская академияУзбекистанTashkent Medical AcademyUzbekistan2025040620252921726Copyright © Каримджанов И.А., Исканова Г.Х., Мадаминова М.Ш., Газиева А.С., Тогаев М.К., 20252025Каримджанов И.А., Исканова Г.Х., Мадаминова М.Ш., Газиева А.С., Тогаев М.К.Karimdzhanov I.A., Iskanova G.K., Madaminova M.S., Gazieva A.S., Togaev M.K.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.nephrolog.ru/jour/article/view/2415

В статье представлен обзор современных представлений о факторах риска хронической болезни почек (ХБП) и сердечно-сосудистых заболеваний в педиатрической популяции. Рассмотрены группы основных структурных и функциональных маркеров у детей с артериальной гипертензией и при ХБП у детей. Приведены результаты исследований, подтверждающих их ценность в отношении скрининга, диагностики и оценки сердечно-сосудистого прогноза. Обсуждены различия в подходах к использованию биомаркеров у взрослых и детей.

The article provides an overview of current understanding of the risk factors for chronic kidney disease (CKD) and cardiovascular diseases in the pediatric population. The groups of the main structural and functional markers in children with arterial hypertension and CKD in children are considered. The results of studies confirming their value in terms of screening, diagnosis, and assessment of cardiovascular prognosis are presented. Differences in approaches to the use of biomarkers in adults and children are discussed.

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The authors declare that there are no conflicts of interest present.