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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nefr</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology (Saint-Petersburg)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-6274</issn><issn pub-type="epub">2541-9439</issn><publisher><publisher-name>Pavlov First Saint-Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/1561-6274-2017-21-2-10-19</article-id><article-id custom-type="elpub" pub-id-type="custom">nefr-247</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПЕРЕДОВАЯ СТАТЬЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LEADING ARTICLE</subject></subj-group></article-categories><title-group><article-title>ОЖИРЕНИЕ И ЗАБОЛЕВАНИЯ ПОЧЕК: СКРЫТЫЕ ПОСЛЕДСТВИЯ ЭПИДЕМИИ</article-title><trans-title-group xml:lang="en"><trans-title>OBESITY AND KIDNEY DISEASE: HIDDEN CONSEQUENCES OF THE EPIDEMIC</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ковесди</surname><given-names>Чаба П.</given-names></name><name name-style="western" xml:lang="en"><surname>Kovesdy</surname><given-names>Csaba P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Отделение Нефрологии Медицинского факультета Научного Центра Здоровья Университета, Отдел Нефрологии Медицинского центра</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фурс</surname><given-names>Сьюзан</given-names></name><name name-style="western" xml:lang="en"><surname>Furth</surname><given-names>Susan</given-names></name></name-alternatives><bio xml:lang="ru"><p>Отделение Педиатрии Медицинской школа Перельмана</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зоккали</surname><given-names>Кармин</given-names></name><name name-style="western" xml:lang="en"><surname>Zoccali</surname><given-names>Carmine</given-names></name></name-alternatives><bio xml:lang="ru"><p>Центр Научных Исследований Института, , Отдел Клинической Эпидемиологии и Патофизиологии Заболеваний Почек и Гипертензии, Калабрия</p></bio><bio xml:lang="en"><p>IFC Clinical Epidemiology and Pathophysiology of Renal Diseases and Hypertension, Reggio Calabria</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Университет Теннесси, Мемфис, Теннесси; &#13;
Мемфисский Медицинский Центр Ветеранов Армии</institution><country>Соединённые Штаты Америки</country></aff><aff xml:lang="en"><institution>University of Tennessee Health Science Center, Memphis, TN; &#13;
Memphis VA Medical Center, Memphis, TN</institution><country>United States</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Университет Пенсильвании, Филадельфия, Пенсильвания</institution><country>Соединённые Штаты Америки</country></aff><aff xml:lang="en"><institution>University of Pennsylvania, Philadelphia, PA</institution><country>United States</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Институт Клинической Физиологии</institution><country>Италия</country></aff><aff xml:lang="en"><institution>CNR</institution><country>Italy</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>03</day><month>03</month><year>2017</year></pub-date><volume>21</volume><issue>2</issue><fpage>10</fpage><lpage>19</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ковесди Ч., Фурс С., Зоккали К., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Ковесди Ч., Фурс С., Зоккали К.</copyright-holder><copyright-holder xml:lang="en">Kovesdy C., Furth S., Zoccali C.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephrolog.ru/jour/article/view/247">https://journal.nephrolog.ru/jour/article/view/247</self-uri><abstract><p>От имени Организационного Комитета Всемирного Дня Почки</p><p>Ожирение стало всемирной эпидемией, и, по прогнозам, его распространенность в ближайшем десятилетии увеличится на 40%. Растущая распространенность ожирения оказывает влияние на риск развития сахарного диабета, сердечно-сосудистых заболеваний, а также хронической болезни почек (ХБП). Высокий индекс массы тела – один из наиболее значимых факторов риска ХБП. У лиц с ожирением в ответ на увеличение метаболических потребностей избыточной массы тела развивается компенсаторная гиперфильтрация. Увеличение внутриклубочкового давления может привести к повреждению почек и повышению риска развития ХБП в отдаленном периоде. В последние годы частота развития гломерулопатии, ассоциированной с ожирением, выросла в 10 раз. Кроме того, показано, что ожирение является фактором риска нефролитиаза и ряда злокачественных новообразований, в том числе рака почки. В этом году Инициатива «Всемирный День Почки» выдвигает образовательную программу, которая разъясняет опасные последствия ожирения и его связь с заболеваниями почек, пропагандирует здоровый образ жизни и мероприятия по его формированию как доступную основу профилактики неблагоприятных последствий ожирения.</p></abstract><trans-abstract xml:lang="en"><p>on behalf of the World Kidney Day Steering Committee. </p><p>Obesity has become a worldwide epidemic, and its prevalence has been projected to grow by 40% in the next decade. This increasing prevalence has implications for the risk of diabetes, cardiovascular disease and also for Chronic Kidney Disease. A high body mass index is one of the strongest risk factors for new-onset Chronic Kidney Disease. In individuals affected by obesity, a compensatory hyperfiltration occurs to meet the heightened metabolic demands of the increased body weight. The increase in intraglomerular pressure can damage the kidneys and raise the risk of developing Chronic Kidney Disease in the long-term. The incidence of obesity-related glomerulopathy has increased ten-fold in recent years. Obesity has also been shown to be a risk factor for nephrolithiasis, and for a number of malignancies including kidney cancer. This year the World Kidney Day promotes education on the harmful consequences of obesity and its association with kidney disease, advocating healthy lifestyle and health policy measures that makes preventive behaviors an affordable option.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ожирение</kwd><kwd>хроническая болезнь почек</kwd><kwd>нефролитиаз</kwd><kwd>рак почки</kwd><kwd>профилактика.</kwd></kwd-group><kwd-group xml:lang="en"><kwd>obesity</kwd><kwd>chronic kidney disease</kwd><kwd>nephrolithiasis</kwd><kwd>kidney cancer</kwd><kwd>prevention</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Forouzanfar MH, Alexander L, Anderson HR et al. 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