<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nefr</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology (Saint-Petersburg)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-6274</issn><issn pub-type="epub">2541-9439</issn><publisher><publisher-name>Pavlov First Saint-Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/1561-6274-2017-21-2-20-23</article-id><article-id custom-type="elpub" pub-id-type="custom">nefr-248</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПЕРЕДОВАЯ СТАТЬЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LEADING ARTICLE</subject></subj-group></article-categories><title-group><article-title>ПРОБЛЕМА ОЦЕНКИ СКОРОСТИ КЛУБОЧКОВОЙ ФИЛЬТРАЦИИ ПРИ ОЖИРЕНИИ</article-title><trans-title-group xml:lang="en"><trans-title>PROBLEM OF THE ASSESMENT OF GLOMERULAR FILTRATION RATE IN OBESITY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Смирнов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Smirnov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Профессор Смирнов Алексей Владимирович</p><p>Кафедра пропедевтики внутренних болезней, Научно-исследовательский институт нефрологии, директор.</p><p>197022, Россия, Санкт-Петербург, ул. Л. Толстого, д. 17,корп. 54.</p></bio><bio xml:lang="en"><p>Prof. Alexey V. Smirnov MD, PhD, DMedSci. Institute of Nephrology, director197022, Russia, St-Petersburg, L.Tolstoy st. 17, build. 54 </p></bio><email xlink:type="simple">smirnov@nephrolog.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каюков</surname><given-names>И. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kayukov</surname><given-names>I. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Профессор Каюков Иван Глебович </p><p>Научно-исследовательский институт нефрологии, лаборатория клинической физиологии почек, заведующий. </p><p>197022, Россия, Санкт-Петербург, ул. Л. Толстого, д. 17, корп. 54. </p></bio><bio xml:lang="en"><p>Prof. Ivan G. Kayukov MD, PhD, DMedSci.</p><p>Institute of Nephrology, Laboratory of Clinical Physiology of theKidney, head.</p><p>197022 Russia, St-Petersburg, L. Tolstoy st. 17, build. 54 </p></bio><email xlink:type="simple">kvaka55@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Румянцев</surname><given-names>А. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Rumyantsev</surname><given-names>A. Sh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Профессор Румянцев Александр Шаликович </p><p>Кафедра факультетской терапии медицинского факультета СПбГУ</p><sec><title> </title></sec></bio><bio xml:lang="en"><p>Prof. Alexandr Sh.Rumyantsev MD, PhD, DMedSci </p><p>Department of Faculty Therapy.</p><p>199106, Saint Petersburg, V.O., 21 line 8a.</p></bio><email xlink:type="simple">rash.56@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова &#13;
Россия</institution><country>Россия</country></aff><aff xml:lang="en"><institution>First Pavlov Saint Petersburg State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>First Pavlov Saint Petersburg State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова;&#13;
Санкт-Петербургский государственный университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint Petersburg State University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>03</day><month>03</month><year>2017</year></pub-date><volume>21</volume><issue>2</issue><fpage>20</fpage><lpage>23</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Смирнов А.В., Каюков И.Г., Румянцев А.Ш., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Смирнов А.В., Каюков И.Г., Румянцев А.Ш.</copyright-holder><copyright-holder xml:lang="en">Smirnov A.V., Kayukov I.G., Rumyantsev A.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephrolog.ru/jour/article/view/248">https://journal.nephrolog.ru/jour/article/view/248</self-uri><abstract><p>В статье обсуждается проблема выбора адекватного метода оценки скорости клубочковой фильтрации при избыточной массе тела и ожирении.</p></abstract><trans-abstract xml:lang="en"><p>The article discusses the problem of choosing an adequate method of assessing glomerular filtration rate in overweight and obesity.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>масса тела</kwd><kwd>ожирение</kwd><kwd>скорость клубочковой фильтрации</kwd></kwd-group><kwd-group xml:lang="en"><kwd>weight</kwd><kwd>obesity</kwd><kwd>glomerular filtration rate</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">National Kidney Foundation. K/DOQI Clinical Practice Guidelines for Chronic Kidney Disease: evaluation, classification, and stratification. Am J Kidney Dis 2002;39(suppl 1):S1-S266</mixed-citation><mixed-citation xml:lang="en">National Kidney Foundation. K/DOQI Clinical Practice Guidelines for Chronic Kidney Disease: evaluation, classification, and stratification. Am J Kidney Dis 2002;39(suppl 1):S1-S266</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Gruer L, Hart CL, Watt GC. After 50 years and 200 papers, what can the Midspan cohort studies tell us about our mortality? Public Health 2017;142:186-195. doi: 10.1016/j. puhe.2015.06.017</mixed-citation><mixed-citation xml:lang="en">Gruer L, Hart CL, Watt GC. After 50 years and 200 papers, what can the Midspan cohort studies tell us about our mortality? Public Health 2017;142:186-195. doi: 10.1016/j. puhe.2015.06.017</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Ricci MA, De Vuono S, Scavizzi M. et al. Facing Morbid Obesity: How to Approach It. Angiology 2016;67(4):391-397. doi: 10.1177/0003319715595735</mixed-citation><mixed-citation xml:lang="en">Ricci MA, De Vuono S, Scavizzi M. et al. Facing Morbid Obesity: How to Approach It. Angiology 2016;67(4):391-397. doi: 10.1177/0003319715595735</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Freedman DS, Centers for Disease Control and Prevention (CDC). Obesity – United States, 1988-2008. MMWR Suppl 2011; 60(1):73-77</mixed-citation><mixed-citation xml:lang="en">Freedman DS, Centers for Disease Control and Prevention (CDC). Obesity – United States, 1988-2008. MMWR Suppl 2011; 60(1):73-77</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Finkelstein EA, Khavjou OA, Thompson H et al. Obesity and severe obesity forecasts through 2030. Am J Prev Med 2012; 42(6):563-570</mixed-citation><mixed-citation xml:lang="en">Finkelstein EA, Khavjou OA, Thompson H et al. Obesity and severe obesity forecasts through 2030. Am J Prev Med 2012; 42(6):563-570</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Mack KA, Centers for Disease Control and Prevention (CDC). Drug-induced deaths – United States, 1999-2010. MMWR Suppl 2013; 62(3):161-163</mixed-citation><mixed-citation xml:lang="en">Mack KA, Centers for Disease Control and Prevention (CDC). Drug-induced deaths – United States, 1999-2010. MMWR Suppl 2013; 62(3):161-163</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Vivante A, Golan E, Tzur D et al. Body mass index in 1.2 million adolescents and risk for end-stage renal disease. Arch Intern Med 2012;172(21):1644-1650 DOI: 10.1001/2013.jamainternmed. 85</mixed-citation><mixed-citation xml:lang="en">Vivante A, Golan E, Tzur D et al. Body mass index in 1.2 million adolescents and risk for end-stage renal disease. Arch Intern Med 2012;172(21):1644-1650 DOI: 10.1001/2013.jamainternmed. 85</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Salazar DE, Corcoran GB. Predicting creatinine clearance and renal drug clearance in obese patients from estimated fat-free body mass. Am J Med 1988;84: 1053-1060</mixed-citation><mixed-citation xml:lang="en">Salazar DE, Corcoran GB. Predicting creatinine clearance and renal drug clearance in obese patients from estimated fat-free body mass. Am J Med 1988;84: 1053-1060</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Lemoine S, Guebre-Egziabher F, Sens F. Accuracy of GFR estimation in obese patients. Clin J Am Soc Nephrol 2014;9(4):720727. doi: 10.2215/CJN.03610413</mixed-citation><mixed-citation xml:lang="en">Lemoine S, Guebre-Egziabher F, Sens F. Accuracy of GFR estimation in obese patients. Clin J Am Soc Nephrol 2014;9(4):720727. doi: 10.2215/CJN.03610413</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Cockroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron 1976;16:31-41</mixed-citation><mixed-citation xml:lang="en">Cockroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron 1976;16:31-41</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Levey AS, Coresh J, Greene T et al. Chronic Kidney Disease Epidemiology Collaboration. Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate. Ann Intern Med 2006 Aug 15; 145(4):247-254</mixed-citation><mixed-citation xml:lang="en">Levey AS, Coresh J, Greene T et al. Chronic Kidney Disease Epidemiology Collaboration. Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate. Ann Intern Med 2006 Aug 15; 145(4):247-254</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Levey AS, Stevens LA, Frcp C. et al. A New Equation to Estimate Glomerular Filtration Rate. Ann Intern Med 2009;150:604-612</mixed-citation><mixed-citation xml:lang="en">Levey AS, Stevens LA, Frcp C. et al. A New Equation to Estimate Glomerular Filtration Rate. Ann Intern Med 2009;150:604-612</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Michels WM, Grootendorst DC, Verduijn M et al. Performance of the Cockcroft-Gault, MDRD, and new CKD-EPI formulas in relation to GFR, age, and body size. Clin J Am Soc Nephrol 2010; 5: 1003-1009</mixed-citation><mixed-citation xml:lang="en">Michels WM, Grootendorst DC, Verduijn M et al. Performance of the Cockcroft-Gault, MDRD, and new CKD-EPI formulas in relation to GFR, age, and body size. Clin J Am Soc Nephrol 2010; 5: 1003-1009</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Earley A, Miskulin D, Lamb EJ et al. Estimating equations for glomerular filtration rate in the era of creatinine standardization: A systematic review. Ann Intern Med 2012; 156: 785-795</mixed-citation><mixed-citation xml:lang="en">Earley A, Miskulin D, Lamb EJ et al. Estimating equations for glomerular filtration rate in the era of creatinine standardization: A systematic review. Ann Intern Med 2012; 156: 785-795</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Fox CS, Larson MG, Leip EP et al. Predictors of new-onset kidney disease in a community-based population. JAMA 2004; 291: 844-850</mixed-citation><mixed-citation xml:lang="en">Fox CS, Larson MG, Leip EP et al. Predictors of new-onset kidney disease in a community-based population. JAMA 2004; 291: 844-850</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Jesudason DR, Clifton P. Interpreting different measures of glomerular filtration rate in obesity and weight loss: pitfalls for the clinician. Int J Obes (Lond) 2012; 36(11):1421-1427</mixed-citation><mixed-citation xml:lang="en">Jesudason DR, Clifton P. Interpreting different measures of glomerular filtration rate in obesity and weight loss: pitfalls for the clinician. Int J Obes (Lond) 2012; 36(11):1421-1427</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Ozmen S, Kaplan MA, Kaya H et al. Role of lean body mass for estimation of glomerular filtration rate in patients with chronic kidney disease with various body mass indices. Scand J Urol Nephrol 2009; 43:171-176</mixed-citation><mixed-citation xml:lang="en">Ozmen S, Kaplan MA, Kaya H et al. Role of lean body mass for estimation of glomerular filtration rate in patients with chronic kidney disease with various body mass indices. Scand J Urol Nephrol 2009; 43:171-176</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Lim WH, Lim EM, McDonald S. Lean body mass-adjusted Cockcroft and Gault formula improves the estimation of glomerular filtration rate in subjects with normal-range serum creatinine. Nephrology (Carlton) 2006; 11: 250-256</mixed-citation><mixed-citation xml:lang="en">Lim WH, Lim EM, McDonald S. Lean body mass-adjusted Cockcroft and Gault formula improves the estimation of glomerular filtration rate in subjects with normal-range serum creatinine. Nephrology (Carlton) 2006; 11: 250-256</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Vitolo E, Santini E, Salvati A et al. Metabolic and Hormonal Determinants of Glomerular Filtration Rate and Renal Hemodynamics in Severely Obese Individuals. Obes Facts 2016;9(5):310-320</mixed-citation><mixed-citation xml:lang="en">Vitolo E, Santini E, Salvati A et al. Metabolic and Hormonal Determinants of Glomerular Filtration Rate and Renal Hemodynamics in Severely Obese Individuals. Obes Facts 2016;9(5):310-320</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Bouquegneau A, Vidal-Petiot E, Vrtovsnik F et al. Modification f Diet in Renal Disease versus Chronic Kidney Disease Epidemiology Collaborationequation to estimate glomerular filtration rate in obese patients. Nephrol Dial Transplant 2013;28 Suppl 4:iv122-30. doi: 10.1093/ndt/gft329</mixed-citation><mixed-citation xml:lang="en">Bouquegneau A, Vidal-Petiot E, Vrtovsnik F et al. Modification f Diet in Renal Disease versus Chronic Kidney Disease Epidemiology Collaborationequation to estimate glomerular filtration rate in obese patients. Nephrol Dial Transplant 2013;28 Suppl 4:iv122-30. doi: 10.1093/ndt/gft329</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Nguyen MT, Fong J, Ullah S. et al. Estimating glomerular filtration rate in obese subjects. Obes Res Clin Pract 2015;9(2):152-157</mixed-citation><mixed-citation xml:lang="en">Nguyen MT, Fong J, Ullah S. et al. Estimating glomerular filtration rate in obese subjects. Obes Res Clin Pract 2015;9(2):152-157</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Marwyne MN, Loo CY, Halim AG et al. Estimation of glomerular filtration rate using serum cystatin C in overweight and obese subjects. Med J Malaysia 2011;66(4):313-317</mixed-citation><mixed-citation xml:lang="en">Marwyne MN, Loo CY, Halim AG et al. Estimation of glomerular filtration rate using serum cystatin C in overweight and obese subjects. Med J Malaysia 2011;66(4):313-317</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Lemoine S, Panaye M, Pelletier C. et al. Cystatin C-Creatinine Based Glomerular Filtration Rate Equation in Obese Chronic Kidney Disease Patients: Impact of Deindexation and Gender. Am J Nephrol 2016;44(1):63-70</mixed-citation><mixed-citation xml:lang="en">Lemoine S, Panaye M, Pelletier C. et al. Cystatin C-Creatinine Based Glomerular Filtration Rate Equation in Obese Chronic Kidney Disease Patients: Impact of Deindexation and Gender. Am J Nephrol 2016;44(1):63-70</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Kang YH, Jeong DW, Son SM.Prevalence of Reduced Kidney Function by Estimated Glomerular Filtration Rate Using an Equation Based on Creatinine and Cystatin C in Metabolic Syndrome and Its Components in Korean Adults. Endocrinol Metab (Seoul) 2016;31(3):446-453</mixed-citation><mixed-citation xml:lang="en">Kang YH, Jeong DW, Son SM.Prevalence of Reduced Kidney Function by Estimated Glomerular Filtration Rate Using an Equation Based on Creatinine and Cystatin C in Metabolic Syndrome and Its Components in Korean Adults. Endocrinol Metab (Seoul) 2016;31(3):446-453</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Serpa Neto A, Rossi FM, Amarante RD, Rossi M. Predictive performance of 12 equations for estimating glomerular filtration rate in severely obese patients. Einstein (Sao Paulo) 2011;9(3):294-301. doi: 10.1590/S1679-45082011AO1922</mixed-citation><mixed-citation xml:lang="en">Serpa Neto A, Rossi FM, Amarante RD, Rossi M. Predictive performance of 12 equations for estimating glomerular filtration rate in severely obese patients. Einstein (Sao Paulo) 2011;9(3):294-301. doi: 10.1590/S1679-45082011AO1922</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
