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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nefr</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology (Saint-Petersburg)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-6274</issn><issn pub-type="epub">2541-9439</issn><publisher><publisher-name>Pavlov First Saint-Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.36485/1561-6274-2026-30-2-49-53</article-id><article-id custom-type="edn" pub-id-type="custom">HFPWUJ</article-id><article-id custom-type="elpub" pub-id-type="custom">nefr-2573</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ. КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES. CLINICAL INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>Хроническая болезнь почек у больных, перенесших острое повреждение почек при COVID-19</article-title><trans-title-group xml:lang="en"><trans-title>Chronic kidney disease in patients with acute kidney disease associated with COVID-19</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0881-0599</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Степанов</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Stepanov</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Степанов Вадим Анатольевич, старший научный сотрудник, канд. мед. наук, хирургическое отделение трансплантологии и гемодиализа</p><p>129110, Москва, ул. Щепкина, д. 61/2, корп. 9</p></bio><bio xml:lang="en"><p>Senior Researcher Vadim Anatolyevich Stepanov, MD, PhD, Surgical unit of Transplantology and Hemodialysis</p><p>129110, Moscow, Shchepkina, 61/2, Building 9 </p></bio><email xlink:type="simple">vedmak_@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8497-0693</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ватазин</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vatazin</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ватазин Андрей Владимирович, проф., д-р мед. наук, кафедра трансплантологии, нефрологии и искусственных органов, заведующий кафедрой</p><p>129110, Москва, ул. Щепкина, д. 61/2, корп. 9</p></bio><bio xml:lang="en"><p>Prof. Andrey Vladimirovich Vatazin, MD, PhD, DMedSci, Department of Transplantology, Nephrology, and Artifi cial Organs, Head of Department</p><p>129110, Moscow, Shchepkina, 61/2, Building 9 </p></bio><email xlink:type="simple">vatazin@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-2567-125X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Головина</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Golovina</surname><given-names>E. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Головина Елена Николаевна, аспирант, кафедра трансплантологии, нефрологии и искусственных органов</p><p>129110, Москва, ул. Щепкина, д. 61/2, корп. 9</p></bio><bio xml:lang="en"><p>Postgraduate student Elena Nikolaevna Golovina, MD, Department of Transplantology, Nephrology, and Artificial Organs</p><p>129110, Moscow, Shchepkina, 61/2, Building 9 </p></bio><email xlink:type="simple">elena_golovina81@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6010-8975</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Артамонова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Artamonova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Артамонова Александра Анатольевна, старший научный сотрудник, канд. мед. наук, хирургическое отделение трансплантологии и гемодиализа</p><p>129110, Москва, ул. Щепкина, д. 61/2, корп. 9</p></bio><bio xml:lang="en"><p>Senior Researcher Alexandra Anatolyevna Artamonova, MD, PhD, Surgical unit of Transplantology and Hemodialysis</p><p>129110, Moscow, Shchepkina, 61/2, Building 9 </p></bio><email xlink:type="simple">aartamonova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Regional Research Clinical Institute</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>26</day><month>07</month><year>2026</year></pub-date><volume>30</volume><issue>2</issue><fpage>49</fpage><lpage>53</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Степанов В.А., Ватазин А.В., Головина Е.Н., Артамонова А.А., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Степанов В.А., Ватазин А.В., Головина Е.Н., Артамонова А.А.</copyright-holder><copyright-holder xml:lang="en">Stepanov V.A., Vatazin A.V., Golovina E.N., Artamonova A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephrolog.ru/jour/article/view/2573">https://journal.nephrolog.ru/jour/article/view/2573</self-uri><abstract><p>Нами проанализированы электронные истории болезни 769 пациентов, госпитализированных в МОНИКИ им. М.Ф. Владимирского с положительным результатом теста на SARS-CoV-2 методом полимеразной цепной реакции в носоглотке. Острое повреждение почек (ОПП) осложнило течение COVID-19 у 350 (46 %) больных. Из 350 больных с ОПП умерли 132 больных, что составило 37,7 %, выжили 218 больных (62,3 %). В анализируемую когорту с ОПП вошли пациенты с тяжёлым и критическим течением коронавирусной болезни. Тяжесть состояния больных определялась почти тотальным поражением легких (КТ 3–4 у 308 больных, 40,1 %), необходимостью ИВЛ (320 больных, 42 %), коморбидностью этих больных (сахарный диабет 28,6 % больных, артериальная гипертензия 81,1 %, ожирение 21,1 % больных). В постковидном периоде из 218 выживших больных с ОПП хронизация процесса в почках отмечена у 169 больных (77,5 %). Чаще всего зафиксирована ХБП С3а (42 % больных), реже отмечалась 2-я стадия ХБП (36,1 %), С3б была у 15,9 % больных. Таким образом, больные, перенесшие ОПП при COVID-19, подвержены развитию ХБП в постковидном периоде, что диктует необходимость их диспансерного наблюдения с целью раннего выявления нарушений функции почек и назначения нефропротективной терапии.</p></abstract><trans-abstract xml:lang="en"><p>We analyzed the electronic medical records of 769 patients hospitalized at the Vladimirsky Regional Scientific Research Institute (MONIKI) with a positive nasopharyngeal polymerase chain reaction (PCR) test for SARS-CoV2. Acute kidney failure complicated the course of COVID-19 in 350 patients (46 %). Of the 350 patients with acute kidney failure, 132 died (37.7 %), and 218 patients (62.3 %) survived. The analyzed cohort of patients with acute kidney failure included patients with severe and critical COVID-19. The severity of the patients' condition was determined by near-total lung damage (CT scan 3-4 in 308 patients, 40.1 %), the need for mechanical ventilation (320 patients, 42 %), and comorbidities (diabetes mellitus in 28.6 % of patients, hypertension in 81.1 %, obesity in 21.1 %). In the post-COVID period, of 218 surviving patients with AKI, chronic kidney disease was observed in 169 patients (77.5 %). CKD C3a was the most common type (42 % of patients), while stage 2 CKD was less common (36.1 %). CKD C3b was observed in 15.9 % of patients. Thus, patients who have experienced acute kidney injury (AKI) during COVID-19 are susceptible to developing chronic kidney disease (CKD) in the post-COVID period, which necessitates their follow-up observation for the early detection of renal dysfunction and the prescription of nephroprotective therapy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>новая коронавирусная инфекция</kwd><kwd>COVID-19</kwd><kwd>SARS-CoV-2</kwd><kwd>хроническая болезнь почек</kwd><kwd>острое повреждение почек</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Novel coronavirus infection</kwd><kwd>COVID-19</kwd><kwd>SARS-CoV-2</kwd><kwd>chronic kidney disease</kwd><kwd>acute kidney injury</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Jansen J, Reimer KK, Nagai JS et al. SARS-CoV-2 infects human kidneys and induces fibrosis in renal organoids. 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