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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nefr</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology (Saint-Petersburg)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-6274</issn><issn pub-type="epub">2541-9439</issn><publisher><publisher-name>Pavlov First Saint-Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/1561-6274-2017-21-4-9-29</article-id><article-id custom-type="elpub" pub-id-type="custom">nefr-275</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПЕРЕДОВАЯ СТАТЬЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LEADING ARTICLE</subject></subj-group></article-categories><title-group><article-title>СНИЖЕНИЕ ФИЗИЧЕСКОЙ РАБОТОСПОСОБНОСТИ У БОЛЬНЫХ, ПОЛУЧАЮЩИХ ЗАМЕСТИТЕЛЬНУЮ ПОЧЕЧНУЮ ТЕРАПИЮ: ФОКУС НА САРКОПЕНИЮ</article-title><trans-title-group xml:lang="en"><trans-title>DECLINE OF PHYSICAL PERFORMANCE IN PATIENTS RECEIVING RENAL REPLACEMENT THERAPY: FOCUS ON SARCOPENIA</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Смирнов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Smirnov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук</p><p>Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова, Научно-исследовательский институт нефрологии, директор.</p><p>197022, Россия, Санкт-Петербург, ул. Л. Толстого, д. 17, корп. 54. Тел.: (812) 338-69-01</p></bio><bio xml:lang="en"><p>Prof., MD, PhD, DMedSci.</p><p>Research Institute of Nephrology, director.</p><p>First Pavlov St-Petersburg State Medical University; Department of propedeutic of internal diseases</p><p>197022, Russia, St-Petersburg, L. Tolstoy st., 17, build. 54, Phone: (812) 338-69- 01; </p></bio><email xlink:type="simple">smirnov@nephrolog.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Голубев</surname><given-names>Р. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Golubev</surname><given-names>R. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук</p><p>Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова, Научно-исследовательский институт нефрологии, лаборатория почечной недостаточности, зав. лабораторией.</p><p>197022, Россия, Санкт-Петербург, ул. Л. Толстого, д. 17, корп. 54. Тел.: (812) 338-69-14;</p></bio><bio xml:lang="en"><p>MD, PhD</p><p>First Pavlov St-Petersburg State Medical University,</p><p>Research Institute of Nephrology, Laboratory of Renal Insufficiency, head.</p><p>197022, Russia, St-Petersburg, L. Tolstoy st., 17, build. 54, Phone: (812) 338-69-14;</p></bio><email xlink:type="simple">romvladgol@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коростелева</surname><given-names>Н. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Korosteleva</surname><given-names>N. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук</p><p>Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова, Научно-исследовательский институт нефрологии, лаборатория почечной недостаточности.</p><p>197022, Россия, Санкт-Петербург, ул. Л. Толстого, д. 17, корп. 54. Тел.: (812) 338-69-14 </p></bio><bio xml:lang="en"><p>MD, PhD</p><p>First Pavlov St-Petersburg State Medical University;</p><p>Research Institute of Nephrology, Laboratory of Renal Insufficiency.</p><p>197022, Russia, St-Petersburg, L. Tolstoy st., 17, build. 54, Phone: (812) 338-69-14</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Румянцев</surname><given-names>А. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Rumyantsev</surname><given-names>A. Sh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Проф.</p><p>Санкт-Петербургский государственный университет, кафедра факультетской терапии.</p><p>Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова, кафедра пропедевтики внутренних болезней.</p><p>Россия, 199106, Санкт-Петербург, 21-я линия В.О., д. 8а., Тел.: +7 (812) 326-03-26</p></bio><bio xml:lang="en"><p>Prof., MD, PhD, DMedSci</p><p>Pavlov First Saint-Petersburg State Medical University, Department of propedeutic of internal diseases;</p><p>Saint Petersburg State University, Department of Faculty Therapy</p><p>Russia, 199106, Saint Petersburg, V.O., 21 line 8a., Phone: +7(812) 326-03-26</p></bio><email xlink:type="simple">rash.56@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова;&#13;
Научно-исследовательский институт нефрологии</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Nephrology;&#13;
Pavlov First St-Petersburg State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>First Pavlov St-Petersburg State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова;&#13;
Санкт-Петербургский государственный университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pavlov First Saint-Petersburg State Medical University;&#13;
Saint Petersburg State University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>05</day><month>07</month><year>2017</year></pub-date><volume>21</volume><issue>4</issue><fpage>9</fpage><lpage>29</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Смирнов А.В., Голубев Р.В., Коростелева Н.Ю., Румянцев А.Ш., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Смирнов А.В., Голубев Р.В., Коростелева Н.Ю., Румянцев А.Ш.</copyright-holder><copyright-holder xml:lang="en">Smirnov A.V., Golubev R.V., Korosteleva N.Y., Rumyantsev A.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephrolog.ru/jour/article/view/275">https://journal.nephrolog.ru/jour/article/view/275</self-uri><abstract><p>Саркопения является важной причиной снижения физической работоспособности у больных, получающих заместительную почечную терапию. Обсуждаются критерии диагностики, механизмы ее развития и методы коррекции.</p></abstract><trans-abstract xml:lang="en"><p>The sarcopenia is an important cause of reduced physical performance in patients receiving renal replacement therapy. Discusses diagnostic criteria, mechanisms of development and methods of correction.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая болезнь почек</kwd><kwd>гемодиализ</kwd><kwd>саркопения</kwd><kwd>физические тренировки</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic kidney disease</kwd><kwd>hemodialysis</kwd><kwd>sarcopenia</kwd><kwd>exercise training</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Rosenberg IH. Epidemiologic and methodologic problems in determining nutritional status of older persons. Am J Clin Nutr 1989; 50(5Suppl):1231–1235</mixed-citation><mixed-citation xml:lang="en">Rosenberg IH. 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