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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nefr</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology (Saint-Petersburg)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-6274</issn><issn pub-type="epub">2541-9439</issn><publisher><publisher-name>Pavlov First Saint-Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/1561-6274-2017-21-4-73-78</article-id><article-id custom-type="elpub" pub-id-type="custom">nefr-282</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ. КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES. CLINICAL INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>ФАКТОРЫ ПРОГРЕССИРОВАНИЯ ВТОРИЧНЫХ ГЛОМЕРУЛОНЕФРИТОВ У ДЕТЕЙ</article-title><trans-title-group xml:lang="en"><trans-title>FACTORS OF PROFGRESSION OF SECONDARY GLOMERULONEPHRITIS IN CHILDREN</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Козыро</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozyro</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доц., канд. мед. наук</p><p>Республика Беларусь, г. Минск, 220116, пр. Дзержинского, д. 83. Белорусский государственный медицинский университет, 1-я кафедра детских болезней.</p></bio><bio xml:lang="en"><p>Associate professor, MD, PhD</p><p>Republic Belarus, Minsk 220116, Dzerzhinski Ave., 83 Belarusian State Medical University First Department of children diseases</p></bio><email xlink:type="simple">kozyroia@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сукало</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sukalo</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Проф., академик, д-р мед.наук</p><p>Республика Беларусь, г. Минск, 220116, пр. Дзержинского, д. 83. Белорусский государственный медицинский университет, 1-я кафедра детских болезней. Заведующий, зам. Председателя Президиума Национальной академии наук Беларуси.</p></bio><bio xml:lang="en"><p>Academic, MD, PhD, DMedSci</p><p>Republic Belarus, Minsk 220116, Dzerzhinski Ave., 83 Belarusian State Medical University First Department of children diseases, Chief, Deputy Chairman of the Presidium of the Belarus National Academy of Sciences.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>1-я кафедра детских болезней Белорусского государственного медицинского университета</institution><country>Беларусь</country></aff><aff xml:lang="en"><institution>1-st Department of children diseases Belarusian State Medical University</institution><country>Belarus</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>05</day><month>07</month><year>2017</year></pub-date><volume>21</volume><issue>4</issue><fpage>73</fpage><lpage>78</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Козыро И.А., Сукало А.В., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Козыро И.А., Сукало А.В.</copyright-holder><copyright-holder xml:lang="en">Kozyro I.A., Sukalo A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephrolog.ru/jour/article/view/282">https://journal.nephrolog.ru/jour/article/view/282</self-uri><abstract><p>В статье представлены современные знания о новых маркерах, применяемых для диагностики и мониторинга активности волчаночного и нефрита при геморрагическом и АНЦА-васкулитах у детей, что может быть использовано в практической работе нефролога для оптимизации проводимого лечения и определения его продолжительности.</p></abstract><trans-abstract xml:lang="en"><p>This article presents the modern data of the new markers for diagnostics and monitoring the activity of lupus nephritis at Henoch-Schoenlein purpura and ANCA vasculitis in children, which can be used in practice of nephrologists to optimize the treatment and determine its duration.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>люпус-нефрит</kwd><kwd>нефрит при геморрагическом васкулите</kwd><kwd>АНЦА-ассоциированный нефрит</kwd><kwd>дети</kwd><kwd>антитела</kwd><kwd>цитокины</kwd></kwd-group><kwd-group xml:lang="en"><kwd>lupus nephritis</kwd><kwd>Henoch-Schoenlein purpura nephritis</kwd><kwd>ANCA-associated nephritis</kwd><kwd>children</kwd><kwd>antibodies</kwd><kwd>cytokines</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Salgado A, Herrera-Diaz C. 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