nefrНефрологияNephrology (Saint-Petersburg)1561-62742541-9439Pavlov First Saint-Petersburg State Medical University10.24884/1561-6274-2012-16-2-111-117nefr-585Research ArticleПРОГРАММА НЕПРЕРЫВНОГО ПОСЛЕДИПЛОМНОГО ОБРАЗОВАНИЯ ПО НЕФРОЛОГИИPROGRAM ON CONTINUOUS POSTGRADUATE EDUCATION ON NEPHROLOGYФЕТАЛЬНОЕ ПРОГРАММИРОВАНИЕ ПАТОЛОГИИ ВЗРОСЛЫХFETAL PROGRAMMING OF PATHOLOGY IN ADULTSСмирноваН. Н.SmirnovaN. N.

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197022, ул. Льва Толстого, д. 6–8, Тел.: 89954566

smirnova2012@yandex.ruКуприенкоН. Б.KuprienkoN. B.

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Санкт-Петербургский государственный медицинский университет им. акад. И.П.ПавловаRussian Federation201210022012162111117Copyright © Смирнова Н.Н., Куприенко Н.Б., 20122012Смирнова Н.Н., Куприенко Н.Б.Smirnova N.N., Kuprienko N.B.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.nephrolog.ru/jour/article/view/585

В обзоре приводятся данные, свидетельствующие о роли условий внутриутробного развития плода в возникновении хронической патологии у взрослого и пожилого индивидуума. Обсуждается значимость массы тела при рождении, связанная с характером питания матери, состоянием плаценты, трофическим статусом плода для развития ожирения, артериальной гипертензии и инсулинорезистентности в постнатальном периоде. Малая масса плода ассоциирована с малым числом нефронов и с высокой уязвимостью почек взрослого.

The review provides data, indicating about the role of intrauterine fetal growth conditions in chronic pathology at adults and aged individuals. The significance of body mass at birth, associated with maternal nutrition, placenta, trophic status of fetus in progression of obesity, arterial hypertension and insulin resistance in postnatal period is discussed. Low body mass of fetus is associated with small number of nephrons, and with high risk of kidney diseases in adults.

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The authors declare that there are no conflicts of interest present.