nefrНефрологияNephrology (Saint-Petersburg)1561-62742541-9439Pavlov First Saint-Petersburg State Medical University10.24884/1561-6274-2012-16-3/1-93-97nefr-600Research ArticleОРИГИНАЛЬНЫЕ СТАТЬИ. КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯORIGINAL ARTICLES. CLINICAL INVESTIGATIONSПОКАЗАТЕЛИ ТРАНСПОРТА КИСЛОРОДА В ОРГАНИЗМЕ БОЛЬНЫХ НА ПРОГРАММНОМ ГЕМОДИАЛИЗЕOXYGEN TRANSPORT’S INDICATORS IN THE ORGANISM OF PATIENTS ON PROGRAM HEMODIALYSISКоростелеваН. Ю.KorostelevaN. Yu.РумянцевА. Ш.RumyantsevA. Sh.

Кафедра пропедевтики внутренних болезней

197022, Санкт-Петербург, ул. Л.Толстого, д. 17

rash.56@mail.ruСмирновА. В.SmirnovA. V.

Кафедра пропедевтики внутренних болезней

Санкт-Петербургский государственный медицинский университет им. акад И.П.ПавловаRussian FederationНИИ нефрологии, Санкт-Петербургский государственный медицинский университет им. акад И.П.ПавловаRussian Federation201210032012163/19397Copyright © Коростелева Н.Ю., Румянцев А.Ш., Смирнов А.В., 20122012Коростелева Н.Ю., Румянцев А.Ш., Смирнов А.В.Korosteleva N.Y., Rumyantsev A.S., Smirnov A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.nephrolog.ru/jour/article/view/600

ЦЕЛЬ ИССЛЕДОВАНИЯ: изучение показателей дыхательной системы у диализных больных в покое. ПАЦИЕНТЫ И МЕТОДЫ. Обследованы 148 пациентов с ХБП 5 стадии, получающие лечение гемодиализом и не имеющие клинических проявлений заболеваний дыхательной системы. У всех выполнена эргоспирометрия, эхокардиография. РЕЗУЛЬТАТЫ. У всех больных в покое легочные объемы были нормальными. Отмечено умеренное снижение диффузионной способности легких (61,6±1,3%) и увеличение альвеолярной вентиляции (6,21±1,39 л/мин). Увеличение вентиляционного эквивалента (51,9±3,1) и снижение кислородного эффекта дыхательного цикла (16,9±0,9 мл/дых) свидетельствовали о значительных энергетических затратах, связанных с обеспечением каждого дыхательного цикла. Отмечалось достоверное увеличение вентиляционно-перфузионного соотношения (1,95±0,62). ЗАКЛЮЧЕНИЕ. Работа дыхательных мышц в покое у больных с ХБП V стадии, получающих лечение гемодиализом, осуществляется неэффективно. Необходимо ее тестирование и проведение регулярных занятий лечебной физкультурой, включающих элементы дыхательной гимнастики.

AIM OF RESEARCH: studying of respiratory system indicators at rest. PATIENTS AND METHODS. Under investigation there were 148 hemodialysis patients without clinical manifestations of pathology of respiratory system. Spiroergometry and echocardiography were used. RESULTS. At all patients in rest pulmonary volumes were normal. Diffusing lung capacity decrease (61,6±1,3 %) and alveolar ventilation increase (6,21±1,39 l/min) was noted. Ventilation equivalent increase (51,9±3,1) and respiratory cycle oxygen effect decrease (16,9±0,9 ml/dyh) indicated significant metabolic cost of each respiratory cycle providing. Actual ventilation-perfusion coefficient increase (1,95±0,62) was noted. CONCLUSION. Work of respiratory muscles in rest at patients with CKD 5 stage receiving hemodialysis treatment is carried out inefficiently. Its testing and carrying out of regular exercise therapy including elements of respiratory gymnastics is necessary.

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The authors declare that there are no conflicts of interest present.