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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nefr</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology (Saint-Petersburg)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-6274</issn><issn pub-type="epub">2541-9439</issn><publisher><publisher-name>Pavlov First Saint-Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/1561-6274-2012-16-3/1-114-116</article-id><article-id custom-type="elpub" pub-id-type="custom">nefr-605</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГЕРИАТРИЧЕСКАЯ НЕФРОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>GERIATRIC NEPHROLOGY</subject></subj-group></article-categories><title-group><article-title>ПОДАГРА И ПОЧКИ: ОСОБЕННОСТИ В ПОЖИЛОМ ВОЗРАСТЕ</article-title><trans-title-group xml:lang="en"><trans-title>GOUT AND KIDNEYS: FEATURES AT ELDERLY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Арьев</surname><given-names>А. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Aryev</surname><given-names>A. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра геронтологии и гериатрии</p><p>193015, Санкт-Петербург, ул. Кирочная, д. 41</p></bio><email xlink:type="simple">ariev_al@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куницкая</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kunitskaya</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра геронтологии и гериатрии</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Андрианова</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Andrainova</surname><given-names>M. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Северо-Западный государственный медицинский университет им. И.И. Мечникова</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>Северо-Западный государственный медицинский университет им. И.И. Мечникова; Федеральный центр сердца, крови и эндокринологии им. В.А. Алмазова, Санкт-Петербург</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-3"><institution>Федеральный центр сердца, крови и эндокринологии им. В.А. Алмазова, Санкт-Петербург</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>10</day><month>03</month><year>2012</year></pub-date><volume>16</volume><issue>3/1</issue><fpage>114</fpage><lpage>116</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Арьев А.Л., Куницкая Н.А., Андрианова М.А., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Арьев А.Л., Куницкая Н.А., Андрианова М.А.</copyright-holder><copyright-holder xml:lang="en">Aryev A.L., Kunitskaya N.A., Andrainova M.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephrolog.ru/jour/article/view/605">https://journal.nephrolog.ru/jour/article/view/605</self-uri><abstract><p>Подагра – системное заболевание, при котором в различных органах и тканях откладываются кристаллы моноурата натрия, и у лиц с гиперурикемией развивается воспаление, обусловленное внешне средовыми и/или генетическими факторами. В настоящее время накоплено много эпидемиологических данных о продолжающемся увеличении гиперурикемии во всем мире. Считается, что подагрой страдают в основном мужчины, однако сейчас наблюдается одинаковая заболеваемость у обоих полов. Недавно проведенные исследования показали растущую распространенность подагры, особенно у лиц пожилого и старческого возраста.</p></abstract><trans-abstract xml:lang="en"><p>Gout is a systemic disease at which monosodium urate cristals deposit in different organs and tissues and in patients with hyperuricemia develops inflammation caused by environmental and/or genetic factors. Nowadays a lot of epidemiological data about worldwide hyperuricemia increasing is accumulated. It is considered, that generally men suffer from gout, but today equal morbidity rate occurs in both men and women. Last researches showed increasing growing prevalence of gout especially in geriatric patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>пожилые</kwd><kwd>диуретики</kwd><kwd>почка</kwd><kwd>сердечно-сосудистые заболевания</kwd><kwd>гипертензия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>elderly</kwd><kwd>diuretics</kwd><kwd>kidney</kwd><kwd>cardiovascular diseases</kwd><kwd>hypertension</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kuzkaya N, Weissmann N, Harrison DG, Dikalov S. Interactions of peroxynitrite with uric acid in the presence of ascorbate and thiols: implications for uncoupling endothelial nitric oxide synthase. Biochem Pharmacol 2005;70(3):343–354</mixed-citation><mixed-citation xml:lang="en">Kuzkaya N, Weissmann N, Harrison DG, Dikalov S. 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