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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nefr</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology (Saint-Petersburg)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-6274</issn><issn pub-type="epub">2541-9439</issn><publisher><publisher-name>Pavlov First Saint-Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/1561-6274-2005-9-4-19-24</article-id><article-id custom-type="elpub" pub-id-type="custom">nefr-710</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>БЛОКАДА ПОЧЕЧНЫХ МИНЕРАЛКОРТИКОИДНЫХ РЕЦЕПТОРОВ: НОВЫЙ ПОДХОД К НЕФРОПРОТЕКТИВНОЙ ТЕРАПИИ ГИПЕРТЕНЗИВНЫХ БОЛЬНЫХ С ХРОНИЧЕСКОЙ БОЛЕЗНЬЮ ПОЧЕК</article-title><trans-title-group xml:lang="en"><trans-title>BLOCKADE OF RENAL MINERALCORTICOID RECEPTORS: A NEW APPROACH TO NEPHROPROTECTIVE THERAPY OF HYPERTENSIVE PATIENTS WITH CHRONIC KIDNEY DISEASE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузьмин</surname><given-names>О. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuzmin</surname><given-names>O. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра фармакологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пугаева</surname><given-names>М. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Pugaeva</surname><given-names>M. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра фармакологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бучнева</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Buchneva</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра фармакологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Оренбургской государственной медицинской академии</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2005</year></pub-date><pub-date pub-type="epub"><day>10</day><month>04</month><year>2005</year></pub-date><volume>9</volume><issue>4</issue><fpage>19</fpage><lpage>24</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кузьмин О.Б., Пугаева М.О., Бучнева Н.В., 2005</copyright-statement><copyright-year>2005</copyright-year><copyright-holder xml:lang="ru">Кузьмин О.Б., Пугаева М.О., Бучнева Н.В.</copyright-holder><copyright-holder xml:lang="en">Kuzmin O.B., Pugaeva M.O., Buchneva N.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephrolog.ru/jour/article/view/710">https://journal.nephrolog.ru/jour/article/view/710</self-uri><abstract><p>Блокада почечных минералкортикоидных рецепторов: новый подход к нефропротективной терапии гипертензивных больных с хронической болезнью почек.</p></abstract><trans-abstract xml:lang="en"><p>Blockade of renal mineralcorticoid receptors: a new approach to nephroprotective therapy of hypertensive patients with chronic kidney disease.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>артериальная гипертония</kwd><kwd>хроническая болезнь почек</kwd><kwd>альдостерон</kwd><kwd>блокада минералкортикоидных рецепторов</kwd></kwd-group><kwd-group xml:lang="en"><kwd>arterial hypertension</kwd><kwd>chronic kidney disease</kwd><kwd>aldosterone</kwd><kwd>aldosterone receptor blockade</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Chobanian A, Bakris GL, Black HR et al. 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