nefrНефрологияNephrology (Saint-Petersburg)1561-62742541-9439Pavlov First Saint-Petersburg State Medical University10.24884/1561-6274-2004-8-1-29-35nefr-810Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESНЕЙРОГУМОРАЛЬНЫЙ ДИСБАЛАНС КАК ПРИЧИНА ДИСФУНКЦИИ ПОЧКИ ПРИ ПЕРВИЧНОЙ АРТЕРИАЛЬНОЙ ГИПЕРТОНИИNEUROHUMORAL DYSBALANCE AS A CAUSE OF RENAL DYSFUNCTION IN PRIMARY ARTERIAL HYPERTENSIONКузьминО. Б.KuzminO. B.

Кафедры фармакологии и госпитальной терапии

ПугаеваМ. О.PugaevaM. O.

Кафедры фармакологии и госпитальной терапии

Оренбургская государственная медицинская академияRussian Federation200410012004812935Copyright © Кузьмин О.Б., Пугаева М.О., 20042004Кузьмин О.Б., Пугаева М.О.Kuzmin O.B., Pugaeva M.O.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.nephrolog.ru/jour/article/view/810

Нейрогуморальный дисбаланс как причина дисфункции почки при первичной артериальной гипертонии.

Neurohumoral dysbalance as a cause of renal dysfunction in primary arterial hypertension.

артериальная гипертониянейрогуморальный дисбалансдисфункция почкиклинические последствияarterial hypertensionneurohumoral dysbalancerenal dysfunctionclinical consequencesReferencesЛебедев АА, Бранчевский ЛЛ, Карышева СС, Кузь мин ОБ. Натрийурез, объем циркулирующей крови при гемодинамических сдвигах, вызванных изменением сосудистого тонуса. Кардиология 1972; 12 (2): 99106Лебедев АА, Бранчевский ЛЛ, Карышева СС, Кузь мин ОБ. Натрийурез, объем циркулирующей крови при гемодинамических сдвигах, вызванных изменением сосудистого тонуса. Кардиология 1972; 12 (2): 99106Guyton AC, Coleman TG, Cowley AW et al. Arterial pressure regulation. Overreading dominance of the kidneys in longterm regulation and in hypertension. Am J Med 1972; 52 (5): 584594Guyton AC, Coleman TG, Cowley AW et al. Arterial pressure regulation. Overreading dominance of the kidneys in longterm regulation and in hypertension. Am J Med 1972; 52 (5): 584594Кузьмин ОБ. Дисфункция почек при сердечной недостаточности и ее лекарственная коррекция. Медицина: М.; 2003: 152Кузьмин ОБ. Дисфункция почек при сердечной недостаточности и ее лекарственная коррекция. Медицина: М.; 2003: 152DiBona GF. Sympathetic nervous system and the kidney in hypertension. Curr Opin Nephrol Hypertens 2002; 11(2): 197 200DiBona GF. Sympathetic nervous system and the kidney in hypertension. Curr Opin Nephrol Hypertens 2002; 11(2): 197 200Ciriello J, de Oliveira CV. Renal afferents and hypertension. Curr Hypertens Rep 2002; 4 (2): 136142Ciriello J, de Oliveira CV. Renal afferents and hypertension. Curr Hypertens Rep 2002; 4 (2): 136142Шустов СБ, Баранов ВЛ, Яковлев ВА, Карлов ВА. Артериальные гипертензии. Специальная литература: СПб; 1997: 320Шустов СБ, Баранов ВЛ, Яковлев ВА, Карлов ВА. Артериальные гипертензии. Специальная литература: СПб; 1997: 320Shirley DG, Unwin RJ. Adrenal steroids and the kidney: 11Іhydroxysteroid dehydrogenase and renal function. J Physiol Proc 2000; 523: 3435Shirley DG, Unwin RJ. Adrenal steroids and the kidney: 11Іhydroxysteroid dehydrogenase and renal function. J Physiol Proc 2000; 523: 3435Elijovich F, Loffer CL, Amador E et al. Regulation of plasma endothelin in saltsensitive hypertension. Circulation 2001; 103 (2): 263268Elijovich F, Loffer CL, Amador E et al. Regulation of plasma endothelin in saltsensitive hypertension. Circulation 2001; 103 (2): 263268Iglarz M, Schiffrin EL. Role of endothelin1 in hypertension. Curr Hypertens Rep 2003; 5 (2):144148Iglarz M, Schiffrin EL. Role of endothelin1 in hypertension. Curr Hypertens Rep 2003; 5 (2):144148Melander O, Fradsen E, Groop L, Hulthen VL. Plasma proANP reflects saltsensitivity in subjects with heredity for hypertension. Hypertension 2002; 39 (5): 996999Melander O, Fradsen E, Groop L, Hulthen VL. Plasma proANP reflects saltsensitivity in subjects with heredity for hypertension. Hypertension 2002; 39 (5): 996999Некрасова АА, Клембовский АА, Левицкая ЮВ и др. Простагландины почек и гипертоническая болезнь. Там же 1986; 16 (3): 1321Некрасова АА, Клембовский АА, Левицкая ЮВ и др. Простагландины почек и гипертоническая болезнь. Там же 1986; 16 (3): 1321Ishimitsu T, Nishikimi T, Saito Y. Plasma levels of adrenomedullin, a newly identified hypotensive peptide, in patients with hypertension and renal failure. J Clin Invest 1999; 94 (5): 21582161Ishimitsu T, Nishikimi T, Saito Y. Plasma levels of adrenomedullin, a newly identified hypotensive peptide, in patients with hypertension and renal failure. J Clin Invest 1999; 94 (5): 21582161Kato J, Kitamura K, Matsui E et al. Plasma adrenomedullin and natriuretic peptides in patients with essential or malignant hypertension. Hypertens Res 1999; 22 (1): 6165Kato J, Kitamura K, Matsui E et al. Plasma adrenomedullin and natriuretic peptides in patients with essential or malignant hypertension. Hypertens Res 1999; 22 (1): 6165Granger JP, Alexander BT, Llinas M. Mechanisms of pressure natriuresis. Curr Hypertens Rep 2002; 4 (2):152159Granger JP, Alexander BT, Llinas M. Mechanisms of pressure natriuresis. Curr Hypertens Rep 2002; 4 (2):152159Guyton AC, Coleman TG, Cowley AW et al. Arterial pressure regulatuon. In: Laragh JH, ed. Hypertension. New York, 1975; 124Guyton AC, Coleman TG, Cowley AW et al. Arterial pressure regulatuon. In: Laragh JH, ed. Hypertension. New York, 1975; 124Weinberger MH, Miller JZ, Senftlerber I et al. Definitions and characteristics of salt sensitivity and blood pressure resistance. Hypertension 1986; 8 (Pt. 2): P.II127 II134Weinberger MH, Miller JZ, Senftlerber I et al. Definitions and characteristics of salt sensitivity and blood pressure resistance. Hypertension 1986; 8 (Pt. 2): P.II127 II134Wienberger MH. Salt sensitivity of blood pressure in humans. Hypertension 1996; 27 (3): 481490Wienberger MH. Salt sensitivity of blood pressure in humans. Hypertension 1996; 27 (3): 481490Su YR, Menon AJ. Epithelial sodium channels and hypertension. Drug Metabol Dispos 2001; 25 (4): 553556Su YR, Menon AJ. Epithelial sodium channels and hypertension. Drug Metabol Dispos 2001; 25 (4): 553556Abassi ZA, Ellahham S, Winaver J, Hoffman A. The intrarenal endothelin system and hypertension. News Physiol Sci 2001; 16 (4):152156Abassi ZA, Ellahham S, Winaver J, Hoffman A. The intrarenal endothelin system and hypertension. News Physiol Sci 2001; 16 (4):152156Strazzullo P, Galletti F, Barba J. Altered renal handling of sodium in human hypertension. Hypertension 2003; 41 (5): 10001005Strazzullo P, Galletti F, Barba J. Altered renal handling of sodium in human hypertension. Hypertension 2003; 41 (5): 10001005Johnston RJ, RodrignezIturbe B, Schreiner GF, Herrera Acasba J. Hypertension: a microvascular and tubulointerstitial disease. J Hypertens 2002; [Suppl 3]: S1S7Johnston RJ, RodrignezIturbe B, Schreiner GF, Herrera Acasba J. Hypertension: a microvascular and tubulointerstitial disease. J Hypertens 2002; [Suppl 3]: S1S7Simons JL, Provoost AP, Anderson S et al. Modulation of glomerular hypertension defines susceptibility to progressive glomerular injury. Kidney Int 1994; 46 (3): 396404Simons JL, Provoost AP, Anderson S et al. Modulation of glomerular hypertension defines susceptibility to progressive glomerular injury. Kidney Int 1994; 46 (3): 396404Semplicini A, Ceolotto G, Sartori M et al. Regulation of glomerular filtration in essential hypertension: role of abnormal Na+ transport and atrial natriuretic peptide. J Nephrol 2002; 15, (5): 489496Semplicini A, Ceolotto G, Sartori M et al. Regulation of glomerular filtration in essential hypertension: role of abnormal Na+ transport and atrial natriuretic peptide. J Nephrol 2002; 15, (5): 489496Boffa JJ. Regression of renal vascular and glomerular fibrosis: role of angiotensin II receptor antagonism and matrix metalloproteinases. J Am Soc Nephrol 2003; 14 (5):11321144Boffa JJ. Regression of renal vascular and glomerular fibrosis: role of angiotensin II receptor antagonism and matrix metalloproteinases. J Am Soc Nephrol 2003; 14 (5):11321144Edigo J. Vasoactive hormones and renal sclerosis. Kidney Int 1996; 49 (3): 578597Edigo J. Vasoactive hormones and renal sclerosis. Kidney Int 1996; 49 (3): 578597Redon J. Renal protection with antihypertensive drugs: insights from microalbuminuria studies. J Hypertens 1998; 16: 20912100Redon J. Renal protection with antihypertensive drugs: insights from microalbuminuria studies. J Hypertens 1998; 16: 20912100Tatti P, Pahor M, Byington RP et al. Outcome results of the Fosinopril versus Amlodipine Cardiovascular Events randomized Ttial (FASET) in patients with hypertension and NIDDM. Diabetes Care 1998; 21 (4): 597603Tatti P, Pahor M, Byington RP et al. Outcome results of the Fosinopril versus Amlodipine Cardiovascular Events randomized Ttial (FASET) in patients with hypertension and NIDDM. Diabetes Care 1998; 21 (4): 597603Brown NJ, Vanghan DE, Fogo AV. Aldosterone and PAI 1: implications for renal injury. J Nephrol 2002; 15(3): 230235Brown NJ, Vanghan DE, Fogo AV. Aldosterone and PAI 1: implications for renal injury. J Nephrol 2002; 15(3): 230235Epstein M. Aldosterone as a mediator of progressive renal disease: pathogenetic and clinical implications. Am J Kidney Dis 2001; 37 (4): 677688Epstein M. Aldosterone as a mediator of progressive renal disease: pathogenetic and clinical implications. Am J Kidney Dis 2001; 37 (4): 677688Blasi ER, Rocha R, Rudolph AE et al. Аldosterone/salt induced renal inflammation and fibrosis in hypertensive rats. Kidney Int 2003; 63 (5): 17911798Blasi ER, Rocha R, Rudolph AE et al. Аldosterone/salt induced renal inflammation and fibrosis in hypertensive rats. Kidney Int 2003; 63 (5): 17911798Комаров АП. Новости доказательной медицины. Сердце 2002; 1 (5): 257258Комаров АП. Новости доказательной медицины. Сердце 2002; 1 (5): 257258Boffa JJ, Tharaux PL, Dussaule JC, Chatziantoniou C. Regression of renal vascular fibrosis by endothelin receptor antagonism. Hypertension 2001; 37(2): 490496Boffa JJ, Tharaux PL, Dussaule JC, Chatziantoniou C. Regression of renal vascular fibrosis by endothelin receptor antagonism. Hypertension 2001; 37(2): 490496Gomezgarre D, Ruizortega M, Ortego M et al. Effects and interactions of endothelin1 and angiotensin II on matrix protein expression and synthesis and mesangial cell growth. Hypertension 1996; 27 (5): 885992Gomezgarre D, Ruizortega M, Ortego M et al. Effects and interactions of endothelin1 and angiotensin II on matrix protein expression and synthesis and mesangial cell growth. Hypertension 1996; 27 (5): 885992Rothermund L, Traupe T, Dieterich M et al. Nephroprotective effects of endothelin ET(A) receptor antagonist darusentan in saltsensitive genetic hypertension. Eur J Pharmacol 2003; 68 (3): 209216Rothermund L, Traupe T, Dieterich M et al. Nephroprotective effects of endothelin ET(A) receptor antagonist darusentan in saltsensitive genetic hypertension. Eur J Pharmacol 2003; 68 (3): 209216Trenkner J, Priem F, Bauer C et al. Endothelin receptor A blockade reduced proteinuria and vascular hypertrophy in spontaneously hypertensive rats on highsalt diet in a blood pressureindependent manner. Clin Sci 2002; 103 [Suppl 48]: 385S388STrenkner J, Priem F, Bauer C et al. Endothelin receptor A blockade reduced proteinuria and vascular hypertrophy in spontaneously hypertensive rats on highsalt diet in a blood pressureindependent manner. Clin Sci 2002; 103 [Suppl 48]: 385S388S

The authors declare that there are no conflicts of interest present.