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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nefr</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology (Saint-Petersburg)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-6274</issn><issn pub-type="epub">2541-9439</issn><publisher><publisher-name>Pavlov First Saint-Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/1561-6274-2004-8-2-14-34</article-id><article-id custom-type="elpub" pub-id-type="custom">nefr-828</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>ВЛИЯНИЕ КОЛИЧЕСТВА И КАЧЕСТВА БЕЛКА В РАЦИОНЕ НА ДЕЯТЕЛЬНОСТЬ ПОЧЕК</article-title><trans-title-group xml:lang="en"><trans-title>QUANTITY AND QUALITY OF DIETARY PROTEIN AND THE KIDNEY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кучер</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kucher</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>курс нефрологии и диализа, факультет последипломного обучения</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каюков</surname><given-names>И. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kayukov</surname><given-names>I. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>курс нефрологии и диализа, факультет последипломного обучения</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Есаян</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Essaian</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>курс нефрологии и диализа, факультет последипломного обучения</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ермаков</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ermakov</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>курс нефрологии и диализа, факультет последипломного обучения</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Научно-исследовательский институт нефрологии, Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2004</year></pub-date><pub-date pub-type="epub"><day>10</day><month>02</month><year>2004</year></pub-date><volume>8</volume><issue>2</issue><fpage>14</fpage><lpage>34</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кучер А.Г., Каюков И.Г., Есаян А.М., Ермаков Ю.А., 2004</copyright-statement><copyright-year>2004</copyright-year><copyright-holder xml:lang="ru">Кучер А.Г., Каюков И.Г., Есаян А.М., Ермаков Ю.А.</copyright-holder><copyright-holder xml:lang="en">Kucher A.G., Kayukov I.G., Essaian A.M., Ermakov Y.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephrolog.ru/jour/article/view/828">https://journal.nephrolog.ru/jour/article/view/828</self-uri><abstract><p>Влияние количества и качества белка в рационе на деятельность почек.</p></abstract><trans-abstract xml:lang="en"><p>Quantity and quality of dietary protein and the kidney.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>белковые нагрузки</kwd><kwd>функциональное состояние почек</kwd><kwd>скорость клубочковой фильтрации</kwd></kwd-group><kwd-group xml:lang="en"><kwd>protein loads</kwd><kwd>functional state of the kidneys</kwd><kwd>glomerular filtration rate</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Наточин ЮВ, ред. Физиология водно-солевого обмена и почки. Наука. СПб,1993</mixed-citation><mixed-citation xml:lang="en">Наточин ЮВ, ред. Физиология водно-солевого обмена и почки. Наука. СПб,1993</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Рябов С.И., Наточин Ю.В.,ред. Функциональная нефрология. Лань, СПб.,1997</mixed-citation><mixed-citation xml:lang="en">Рябов С.И., Наточин Ю.В.,ред. Функциональная нефрология. Лань, СПб.,1997</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Gullans RS, Hebert SC. Metabolic basis of ion transport. In: Brenner BM, ed. Brenner &amp; Rector’s: The kidney. W.B. Saunders, Philadlphia et al.: 1998.</mixed-citation><mixed-citation xml:lang="en">Gullans RS, Hebert SC. Metabolic basis of ion transport. In: Brenner BM, ed. Brenner &amp; Rector’s: The kidney. W.B. Saunders, Philadlphia et al.: 1998.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Tannen RL, Nissim I, Sahai A. Hormonal mediators of ammoniogenesis. Kidney Int 1996; 50:1525</mixed-citation><mixed-citation xml:lang="en">Tannen RL, Nissim I, Sahai A. Hormonal mediators of ammoniogenesis. Kidney Int 1996; 50:1525</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Bosch JP, Lauer A, Glabman S. Shortterm protein loading in assessment of patients with renal disease. Am J Med 1984; 77 (5): 873879</mixed-citation><mixed-citation xml:lang="en">Bosch JP, Lauer A, Glabman S. Shortterm protein loading in assessment of patients with renal disease. Am J Med 1984; 77 (5): 873879</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Castellino P, Cirillo D, Casiere D. et al. Elevated dietary protein intake impairs the renal hemodynamic response to hyperaminoacidemia in patients with primary glomerular diseases. Nephron 1991; 58 (2): 164169</mixed-citation><mixed-citation xml:lang="en">Castellino P, Cirillo D, Casiere D. et al. Elevated dietary protein intake impairs the renal hemodynamic response to hyperaminoacidemia in patients with primary glomerular diseases. Nephron 1991; 58 (2): 164169</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Amiel C, Blanchet F, Friedlander G, Nitenberg A. Renal functional reserve. Nephrol Dial Transplant 1990; 5 (9):763 770.</mixed-citation><mixed-citation xml:lang="en">Amiel C, Blanchet F, Friedlander G, Nitenberg A. Renal functional reserve. Nephrol Dial Transplant 1990; 5 (9):763 770.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Braendle E, Kindler J, Sieberth HG. Effects of an acute protein load in comparison to an acute load of essential amino acids on glomerular filtration rate, renal plasma flow, urinary albumin excretion and nitrogen excretion. Nephrol Dial Transplant 1990; 5 (38): 572578</mixed-citation><mixed-citation xml:lang="en">Braendle E, Kindler J, Sieberth HG. Effects of an acute protein load in comparison to an acute load of essential amino acids on glomerular filtration rate, renal plasma flow, urinary albumin excretion and nitrogen excretion. Nephrol Dial Transplant 1990; 5 (38): 572578</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Fliser D, Zeier M, Nowak R, Ritz E. Renal functional reserve in healthy elderly subjects. J Am Soc Nephrol 1993; 3 (7): 1371 1377</mixed-citation><mixed-citation xml:lang="en">Fliser D, Zeier M, Nowak R, Ritz E. Renal functional reserve in healthy elderly subjects. J Am Soc Nephrol 1993; 3 (7): 1371 1377</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">De Santo NG, Anastasio P, Cirillo M et al. Sequential analysis of variation in glomerular filtration rate to calculate the hemodynamic response to a meat meal. Nephrol Dial Transplant 1995; 10 (9): 16291636</mixed-citation><mixed-citation xml:lang="en">De Santo NG, Anastasio P, Cirillo M et al. Sequential analysis of variation in glomerular filtration rate to calculate the hemodynamic response to a meat meal. Nephrol Dial Transplant 1995; 10 (9): 16291636</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Reyes AA, Karl IE, Klahr S. Role of arginine in health and in renal disease. Am J Physiol (Renal, Fluid and Electrolyte Physiology) 1994; 267 (3): F331F346</mixed-citation><mixed-citation xml:lang="en">Reyes AA, Karl IE, Klahr S. Role of arginine in health and in renal disease. Am J Physiol (Renal, Fluid and Electrolyte Physiology) 1994; 267 (3): F331F346</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Simon AHR, Lima PRM, Almerinda M. et al. Renal hemodynamic responses to a chicken or beef meal in normal individuals. Nephrol Dial Transplant 1998; 13 (9): 22612264</mixed-citation><mixed-citation xml:lang="en">Simon AHR, Lima PRM, Almerinda M. et al. Renal hemodynamic responses to a chicken or beef meal in normal individuals. Nephrol Dial Transplant 1998; 13 (9): 22612264</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Bosch JP, Lew S, Glabman S, Lauer A. Renal hemodynamic changes in humans response to protein loading in normal and diseased kidney. Am J Med 1986; 81 (5): 809815</mixed-citation><mixed-citation xml:lang="en">Bosch JP, Lew S, Glabman S, Lauer A. Renal hemodynamic changes in humans response to protein loading in normal and diseased kidney. Am J Med 1986; 81 (5): 809815</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Bilo JH, Schaap GH, Blaak E et al. Effects of chronic and acute protein administration on renal function in patients with chronic renal insufficiency. Nephron 1989; 53 (3):181187</mixed-citation><mixed-citation xml:lang="en">Bilo JH, Schaap GH, Blaak E et al. Effects of chronic and acute protein administration on renal function in patients with chronic renal insufficiency. Nephron 1989; 53 (3):181187</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Kontessis P, Jones S, Dodds R et al. Renal, metabolic and hormonal responses in ingestion of animal and vegetable proteins. Kidney Int 1990; 38(1):136144</mixed-citation><mixed-citation xml:lang="en">Kontessis P, Jones S, Dodds R et al. Renal, metabolic and hormonal responses in ingestion of animal and vegetable proteins. Kidney Int 1990; 38(1):136144</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Pluvio C, de Pascale E, Giordano M et al. Correlation between glomerular morphology and renal haemodynamic response to aminoacid administration in patients with IgA nephropathy. Nephrol Dial Transplant 1996; 11: 24212425</mixed-citation><mixed-citation xml:lang="en">Pluvio C, de Pascale E, Giordano M et al. Correlation between glomerular morphology and renal haemodynamic response to aminoacid administration in patients with IgA nephropathy. Nephrol Dial Transplant 1996; 11: 24212425</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Кучер АГ, Есаян АМ, Шишкина ЛИ и др. Влияние нагрузок растительным и животным белком на функцио нальное состояние почек у здоровых людей. Нефрология 1997; 1(2): 7984</mixed-citation><mixed-citation xml:lang="en">Кучер АГ, Есаян АМ, Шишкина ЛИ и др. Влияние нагрузок растительным и животным белком на функцио нальное состояние почек у здоровых людей. Нефрология 1997; 1(2): 7984</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Кучер АГ, Есаян АМ, Никогосян ЮА и др. Воздей ствие однократных нагрузок умеренными дозами соевого и мясного белка на деятельность почек у здоровых добро вольцев. Нефрология 1998; 2 (2): 5256</mixed-citation><mixed-citation xml:lang="en">Кучер АГ, Есаян АМ, Никогосян ЮА и др. Воздей ствие однократных нагрузок умеренными дозами соевого и мясного белка на деятельность почек у здоровых добро вольцев. Нефрология 1998; 2 (2): 5256</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Кучер АГ, Есаян АМ, Никогосян ЮА и др. Особенно сти функционального ответа почек здоровых людей на на грузки различными видами белка и его дериватов. Нефрология 1999; 3(4): 8190</mixed-citation><mixed-citation xml:lang="en">Кучер АГ, Есаян АМ, Никогосян ЮА и др. Особенно сти функционального ответа почек здоровых людей на на грузки различными видами белка и его дериватов. Нефрология 1999; 3(4): 8190</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Rambausek M, Zeier M, Ritz E. Diatetik und Ernahrungsriehtlinien bei Nierenkrankheiten. Zeitschrift fur arztliche Fortbildung (Jena) 1993; 87( 4): 315322</mixed-citation><mixed-citation xml:lang="en">Rambausek M, Zeier M, Ritz E. Diatetik und Ernahrungsriehtlinien bei Nierenkrankheiten. Zeitschrift fur arztliche Fortbildung (Jena) 1993; 87( 4): 315322</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Heller A, Flombaum C, Shils J et al. The effect of amino acid infusion on the glomerular filtration rate. Kidney Int 1984; 25, (1):167</mixed-citation><mixed-citation xml:lang="en">Heller A, Flombaum C, Shils J et al. The effect of amino acid infusion on the glomerular filtration rate. Kidney Int 1984; 25, (1):167</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Nakamura H, Ito S, Ebe N, Shibata A. Renal effects of different types of protein in healthy volunteer subjects and diabetes patients. Diabetes Cure 1993; 16:10711075</mixed-citation><mixed-citation xml:lang="en">Nakamura H, Ito S, Ebe N, Shibata A. Renal effects of different types of protein in healthy volunteer subjects and diabetes patients. Diabetes Cure 1993; 16:10711075</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Рентц Дун Б, Андерсон Ш, Бреннер Б. Гемодинами ческие основы прогрессирования почечных болезней. Со временная нефрология. Международный нефрологический семинар, ll. М., 1997: 162 – 172</mixed-citation><mixed-citation xml:lang="en">Рентц Дун Б, Андерсон Ш, Бреннер Б. Гемодинами ческие основы прогрессирования почечных болезней. Со временная нефрология. Международный нефрологический семинар, ll. М., 1997: 162 – 172</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Mizuri S, Hayashi I, Ozawa T et al. Effects of oral protein load on glomerular filtration rate in healthy controls and nephritic patients. Nephron 1988; 48(2): 101106</mixed-citation><mixed-citation xml:lang="en">Mizuri S, Hayashi I, Ozawa T et al. Effects of oral protein load on glomerular filtration rate in healthy controls and nephritic patients. Nephron 1988; 48(2): 101106</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Ando A, Kawata T, Hara V et al. Effects of dietary protein intake on renal function in humans. Kidney Int 1989; 36 [Suppl 27]: 64 – 67</mixed-citation><mixed-citation xml:lang="en">Ando A, Kawata T, Hara V et al. Effects of dietary protein intake on renal function in humans. Kidney Int 1989; 36 [Suppl 27]: 64 – 67</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Bankir L, Ahloulay M, Bouby N et al. Is the process of urinary urea concentration responsible for a high glomerular concentration rate? J Am Soc Nephrol 1993; 4 (5):10911103</mixed-citation><mixed-citation xml:lang="en">Bankir L, Ahloulay M, Bouby N et al. Is the process of urinary urea concentration responsible for a high glomerular concentration rate? J Am Soc Nephrol 1993; 4 (5):10911103</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Есаян АМ, Кучер АГ, Каюков ИГ и др. Влияние белко вой нагрузки на функциональное состояние почек у больных хроническим гломерулонефритом. Тер арх 2002; 74(6): 19 24</mixed-citation><mixed-citation xml:lang="en">Есаян АМ, Кучер АГ, Каюков ИГ и др. Влияние белко вой нагрузки на функциональное состояние почек у больных хроническим гломерулонефритом. Тер арх 2002; 74(6): 19 24</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Бреннер БМ. Механизмы прогрессирования болез ней почек. Нефрология 1999; 3(4): 23 – 27</mixed-citation><mixed-citation xml:lang="en">Бреннер БМ. Механизмы прогрессирования болез ней почек. Нефрология 1999; 3(4): 23 – 27</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Chan AYM, Cheng MLL, Keil LC, Myers BD. Functional response of healthy and diseased glomeruli to a large, protein rich meal. J Clin Invest 1988; 81 (1): 245254</mixed-citation><mixed-citation xml:lang="en">Chan AYM, Cheng MLL, Keil LC, Myers BD. Functional response of healthy and diseased glomeruli to a large, protein rich meal. J Clin Invest 1988; 81 (1): 245254</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Кучер АГ, Есаян АМ, Никогосян ЮА, Ермаков ЮА и др. Особенности функционирования почек здоровых лю дей в условиях гиперфильтрации. Нефрология 2000; 4(1): 53 – 58</mixed-citation><mixed-citation xml:lang="en">Кучер АГ, Есаян АМ, Никогосян ЮА, Ермаков ЮА и др. Особенности функционирования почек здоровых лю дей в условиях гиперфильтрации. Нефрология 2000; 4(1): 53 – 58</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Greger R. How does the macula densa sense tubule function? Nephrol Dial Transplant 1997; 12: 22152217</mixed-citation><mixed-citation xml:lang="en">Greger R. How does the macula densa sense tubule function? Nephrol Dial Transplant 1997; 12: 22152217</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Наточин ЮВ. Кальций и почки. В: Рябов СИ, Нато чин ЮВ, ред. Функциональная нефрология. Лань, СПб: 1997</mixed-citation><mixed-citation xml:lang="en">Наточин ЮВ. Кальций и почки. В: Рябов СИ, Нато чин ЮВ, ред. Функциональная нефрология. Лань, СПб: 1997</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Каюков ИГ, Есаян АМ, Кучер АГ, Ермаков ЮА. Роль функциональногемодинамических механизмов в прогрес сировании хронического гломерулонефрита. Нефрология 1998; 2(1): 7 – 14</mixed-citation><mixed-citation xml:lang="en">Каюков ИГ, Есаян АМ, Кучер АГ, Ермаков ЮА. Роль функциональногемодинамических механизмов в прогрес сировании хронического гломерулонефрита. Нефрология 1998; 2(1): 7 – 14</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Brenner B., Meyer T., Hostetter T. Dietary protein intake and the progressive nature of kidney disease: the role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation, and intrinsic renal disease. N Engl J Med 1982; 3: 162169</mixed-citation><mixed-citation xml:lang="en">Brenner B., Meyer T., Hostetter T. Dietary protein intake and the progressive nature of kidney disease: the role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation, and intrinsic renal disease. N Engl J Med 1982; 3: 162169</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Hostetter T, Olson J, Rennke H et al. Hyperfiltration in remnant nephrons: A potentially adverse response to renal ablation. Am J Physiol 1981; 241: 8593</mixed-citation><mixed-citation xml:lang="en">Hostetter T, Olson J, Rennke H et al. Hyperfiltration in remnant nephrons: A potentially adverse response to renal ablation. Am J Physiol 1981; 241: 8593</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Klahr S, Schreiner G, Ichikawa I. The progression of renal disease. N Engl J Med 1988; 318 (25): 16571666</mixed-citation><mixed-citation xml:lang="en">Klahr S, Schreiner G, Ichikawa I. The progression of renal disease. N Engl J Med 1988; 318 (25): 16571666</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Рогов ВА, Кутырина ИМ, Тареева ИЕ и др. Функцио нальный резерв почек при нефротическом синдроме. Тер арх 1990; 62(6): 55 – 58</mixed-citation><mixed-citation xml:lang="en">Рогов ВА, Кутырина ИМ, Тареева ИЕ и др. Функцио нальный резерв почек при нефротическом синдроме. Тер арх 1990; 62(6): 55 – 58</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Зверев КВ, Кутырина ИМ, Герасименко ОИ. Клини ческое значение почечного функционального резерва. Тер арх 1995; (6): 99 – 102</mixed-citation><mixed-citation xml:lang="en">Зверев КВ, Кутырина ИМ, Герасименко ОИ. Клини ческое значение почечного функционального резерва. Тер арх 1995; (6): 99 – 102</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Ter Wee PM, Geerlings W, Rosman JB et al. Testing renal reserve filtration capacity with an amino solution. Nephron 1985; 41: 193199</mixed-citation><mixed-citation xml:lang="en">Ter Wee PM, Geerlings W, Rosman JB et al. Testing renal reserve filtration capacity with an amino solution. Nephron 1985; 41: 193199</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Жук ВА. Роль гиперфильтрации и функционального почечного резерва в диагностике ранних стадий диабети ческой нефропатии. Нефрология 1998; 2(3): 67 – 70</mixed-citation><mixed-citation xml:lang="en">Жук ВА. Роль гиперфильтрации и функционального почечного резерва в диагностике ранних стадий диабети ческой нефропатии. Нефрология 1998; 2(3): 67 – 70</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Guizar JM, Kornhauser C, Malacara JM et al. Renal functional reserve in patients with recently diagnosed type 2 diabetes mellitus with and without microalbuminuria. Nephron 2001; 87 (3): 223230</mixed-citation><mixed-citation xml:lang="en">Guizar JM, Kornhauser C, Malacara JM et al. Renal functional reserve in patients with recently diagnosed type 2 diabetes mellitus with and without microalbuminuria. Nephron 2001; 87 (3): 223230</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Livi R, Teghini L, Pignone A et al. Renal functional reserve is impaired in patients with systemic sclerosis without clinical signs of kidney involvement. Ann Rheum Dis 2002; 61: 682686</mixed-citation><mixed-citation xml:lang="en">Livi R, Teghini L, Pignone A et al. Renal functional reserve is impaired in patients with systemic sclerosis without clinical signs of kidney involvement. Ann Rheum Dis 2002; 61: 682686</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Bosch JP, Saccaggi A, Lauer A et al. Renal functional reserve in humans. Effect of protein intake on glomerular filtration rate. Am J Med 1983; 75(6): 943950</mixed-citation><mixed-citation xml:lang="en">Bosch JP, Saccaggi A, Lauer A et al. Renal functional reserve in humans. Effect of protein intake on glomerular filtration rate. Am J Med 1983; 75(6): 943950</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Кучер А.Г. Лечебное питание у больных с хронической почечной недостаточностью. Дисс. докт. мед. наук. СПб., 2000</mixed-citation><mixed-citation xml:lang="en">Кучер А.Г. Лечебное питание у больных с хронической почечной недостаточностью. Дисс. докт. мед. наук. СПб., 2000</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Hostetter TH. Pathogenesis of diabetic nephropathy. In: Mitch WE, Brenner BM, eds. The progressive nature of renal disease. ChurchillLivingston, New York: 1986; 149166</mixed-citation><mixed-citation xml:lang="en">Hostetter TH. Pathogenesis of diabetic nephropathy. In: Mitch WE, Brenner BM, eds. The progressive nature of renal disease. ChurchillLivingston, New York: 1986; 149166</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">De Santo NG, Capasso G, Anastassio P et al. The renal functional reserve is not altered in children with chronic renal failure. Nephrol Dial Transplant 1987; 2: 396</mixed-citation><mixed-citation xml:lang="en">De Santo NG, Capasso G, Anastassio P et al. The renal functional reserve is not altered in children with chronic renal failure. Nephrol Dial Transplant 1987; 2: 396</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">De Santo NG, Capasso G, Anastassio P et al. The renal functional reserve (RFR) is not altered in children with chronic renal failure (CRF). Kidney Int 1988; 33: 188</mixed-citation><mixed-citation xml:lang="en">De Santo NG, Capasso G, Anastassio P et al. The renal functional reserve (RFR) is not altered in children with chronic renal failure (CRF). Kidney Int 1988; 33: 188</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">De Santo NG, Capasso G, Anastassio P et al. The renal hemodynamic response following meat meal in children with chronic renal failure and in healthy controls. Nephron 1990; 56: 136142</mixed-citation><mixed-citation xml:lang="en">De Santo NG, Capasso G, Anastassio P et al. The renal hemodynamic response following meat meal in children with chronic renal failure and in healthy controls. Nephron 1990; 56: 136142</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">De Santo NG, Anastassio P, Coppola S et al. Renal hemodynamics, plasma amino acids and hormones after a meat meal in progressive nephron loss. Int J Artif Organs 1991; 14: 161168</mixed-citation><mixed-citation xml:lang="en">De Santo NG, Anastassio P, Coppola S et al. Renal hemodynamics, plasma amino acids and hormones after a meat meal in progressive nephron loss. Int J Artif Organs 1991; 14: 161168</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Денисенко ИЛ, Акимова ЛН, Абисова ТО. Определе ние почечного функционального резерва. Клин лаб диагн 2000; (1): 17 – 18</mixed-citation><mixed-citation xml:lang="en">Денисенко ИЛ, Акимова ЛН, Абисова ТО. Определе ние почечного функционального резерва. Клин лаб диагн 2000; (1): 17 – 18</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Gabbai FB. Renal reserve in patients with high blood pressure. Semin Nephrol (Philadelphia ); 1995 15 (5): 482487</mixed-citation><mixed-citation xml:lang="en">Gabbai FB. Renal reserve in patients with high blood pressure. Semin Nephrol (Philadelphia ); 1995 15 (5): 482487</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Алчинбаев МК, Султанова БГ, Карабаева АЖ. Функ циональный почечный резерв у больных с хроническим пи елонефритом. Нефрология 2001; 5 (2):7175</mixed-citation><mixed-citation xml:lang="en">Алчинбаев МК, Султанова БГ, Карабаева АЖ. Функ циональный почечный резерв у больных с хроническим пи елонефритом. Нефрология 2001; 5 (2):7175</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Мухин НА, Дедов ИИ, Шестакова МВ и др. Функцио нальные почечные резервы у больных сахарным диабетом. Тер арх 1990; (2): 107 – 109</mixed-citation><mixed-citation xml:lang="en">Мухин НА, Дедов ИИ, Шестакова МВ и др. Функцио нальные почечные резервы у больных сахарным диабетом. Тер арх 1990; (2): 107 – 109</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Шестакова МВ, Дедов ИИ, Мухин НА и др. Метабо лические и гемодинамические аспекты диабетической не фропатии. Пробл эндокринологии 1993; 39 (3): 22 – 26</mixed-citation><mixed-citation xml:lang="en">Шестакова МВ, Дедов ИИ, Мухин НА и др. Метабо лические и гемодинамические аспекты диабетической не фропатии. Пробл эндокринологии 1993; 39 (3): 22 – 26</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Вандер А. Физиология почек. 5 е международное издание. «Питер», СПб., 2000</mixed-citation><mixed-citation xml:lang="en">Вандер А. Физиология почек. 5 е международное издание. «Питер», СПб., 2000</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Шейнман ДА, ред. Патофизиология почки. Бином, М., 1997</mixed-citation><mixed-citation xml:lang="en">Шейнман ДА, ред. Патофизиология почки. Бином, М., 1997</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Brenner BM, ed. Brenner &amp; Rector’s: The kidney. W.B. Saunders, Philadlphia et al., 1998.</mixed-citation><mixed-citation xml:lang="en">Brenner BM, ed. Brenner &amp; Rector’s: The kidney. W.B. Saunders, Philadlphia et al., 1998.</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Dworkin LD., Brenner BM. The renal circulation. In: Brenner BM, ed. Brenner &amp; Rector’s: The kidney. W.B. Saunders, Philadlphia et al.: 1998</mixed-citation><mixed-citation xml:lang="en">Dworkin LD., Brenner BM. The renal circulation. In: Brenner BM, ed. Brenner &amp; Rector’s: The kidney. W.B. Saunders, Philadlphia et al.: 1998</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Каюков ИГ, Козлов ВВ, Котовой ЮО и др. Спорные аспекты патогенеза нефротических отеков. Тер арх 1990; (11): 145151</mixed-citation><mixed-citation xml:lang="en">Каюков ИГ, Козлов ВВ, Котовой ЮО и др. Спорные аспекты патогенеза нефротических отеков. Тер арх 1990; (11): 145151</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Каюков ИГ, Дегтерева ОА, Никогосян ЮА и др. Фун кциональное состояние почек при нефротическом синдро ме. В: Рябов СИ, ред. Нефротический синдром. Гиппократ, СПб.: 1992; 181196</mixed-citation><mixed-citation xml:lang="en">Каюков ИГ, Дегтерева ОА, Никогосян ЮА и др. Фун кциональное состояние почек при нефротическом синдро ме. В: Рябов СИ, ред. Нефротический синдром. Гиппократ, СПб.: 1992; 181196</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">Dorhout Mees EJ, Geers AB, Koomans HA. Blood volume and sodium retention in the nephrotic syndrome: a controversial pathophysiological concepts. Nephron 1984; 36 (4): 201211</mixed-citation><mixed-citation xml:lang="en">Dorhout Mees EJ, Geers AB, Koomans HA. Blood volume and sodium retention in the nephrotic syndrome: a controversial pathophysiological concepts. Nephron 1984; 36 (4): 201211</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Maddox DA, Bennet CM, Deen WM et al. Determinants of glomerular filtration in experimental glomerulonephritis in the rat. J Clin Invest 1975; 55: 305318</mixed-citation><mixed-citation xml:lang="en">Maddox DA, Bennet CM, Deen WM et al. Determinants of glomerular filtration in experimental glomerulonephritis in the rat. J Clin Invest 1975; 55: 305318</mixed-citation></citation-alternatives></ref><ref id="cit63"><label>63</label><citation-alternatives><mixed-citation xml:lang="ru">Blants RC, Wilson CB. Acute effects of antiglomerular basement membrane antibody on the process of glomerular filtration in the rat. J Clin Invest 1976; 58: 899811</mixed-citation><mixed-citation xml:lang="en">Blants RC, Wilson CB. Acute effects of antiglomerular basement membrane antibody on the process of glomerular filtration in the rat. J Clin Invest 1976; 58: 899811</mixed-citation></citation-alternatives></ref><ref id="cit64"><label>64</label><citation-alternatives><mixed-citation xml:lang="ru">Allison MEM, Wilson CB, Gottshalk CW et al. Pathophysiology of experimental glomerulonephritis in rats. J Clin Invest 1974; 53: 14021420</mixed-citation><mixed-citation xml:lang="en">Allison MEM, Wilson CB, Gottshalk CW et al. Pathophysiology of experimental glomerulonephritis in rats. J Clin Invest 1974; 53: 14021420</mixed-citation></citation-alternatives></ref><ref id="cit65"><label>65</label><citation-alternatives><mixed-citation xml:lang="ru">Ichikawa I, Rennke HG, Hoyer JR et al. Role of intrarenal mechanisms in the impaired salt excretion of experimental nephrotic syndrome. J Clin Invest 1983; 76: 91103</mixed-citation><mixed-citation xml:lang="en">Ichikawa I, Rennke HG, Hoyer JR et al. Role of intrarenal mechanisms in the impaired salt excretion of experimental nephrotic syndrome. J Clin Invest 1983; 76: 91103</mixed-citation></citation-alternatives></ref><ref id="cit66"><label>66</label><citation-alternatives><mixed-citation xml:lang="ru">Firth JD, Raine AEG, Ledingham JGG. Abnormal sodium handling occurs in isolated perfused kidney of the nephrotic rat. Clin Sci 1989; 76: 387395</mixed-citation><mixed-citation xml:lang="en">Firth JD, Raine AEG, Ledingham JGG. Abnormal sodium handling occurs in isolated perfused kidney of the nephrotic rat. Clin Sci 1989; 76: 387395</mixed-citation></citation-alternatives></ref><ref id="cit67"><label>67</label><citation-alternatives><mixed-citation xml:lang="ru">Chang RLS, Robertson CR, Deen WM, Brenner BM. Permselectivity of the glomerular capillary wall to macromolecules. I. Theoretical considerations. Biophys J 1975; 15: 861886</mixed-citation><mixed-citation xml:lang="en">Chang RLS, Robertson CR, Deen WM, Brenner BM. Permselectivity of the glomerular capillary wall to macromolecules. I. Theoretical considerations. Biophys J 1975; 15: 861886</mixed-citation></citation-alternatives></ref><ref id="cit68"><label>68</label><citation-alternatives><mixed-citation xml:lang="ru">Deen WN, Meyers BD, Brenner BM. The glomerular barrier to macromolecules: Theoretical and experimental considerations. In: Brenner B, Stein J. Contemporary Issues in Nephrology: Nephrotic Syndrome. ChurchillLivingston, New York: 1982; 129</mixed-citation><mixed-citation xml:lang="en">Deen WN, Meyers BD, Brenner BM. The glomerular barrier to macromolecules: Theoretical and experimental considerations. In: Brenner B, Stein J. Contemporary Issues in Nephrology: Nephrotic Syndrome. ChurchillLivingston, New York: 1982; 129</mixed-citation></citation-alternatives></ref><ref id="cit69"><label>69</label><citation-alternatives><mixed-citation xml:lang="ru">Шюк О. Функциональное исследование почек. Ави ценум, Прага, 1975</mixed-citation><mixed-citation xml:lang="en">Шюк О. Функциональное исследование почек. Ави ценум, Прага, 1975</mixed-citation></citation-alternatives></ref><ref id="cit70"><label>70</label><citation-alternatives><mixed-citation xml:lang="ru">Swartz RD. Fluid, electrolyte, and acidbase changes during renal failure. In: Kokko JP, Tannen RL, eds. Fluids and electrolytes. W.B. Saunders, Philadelphia et al.: 1986; 548 – 592</mixed-citation><mixed-citation xml:lang="en">Swartz RD. Fluid, electrolyte, and acidbase changes during renal failure. In: Kokko JP, Tannen RL, eds. Fluids and electrolytes. W.B. Saunders, Philadelphia et al.: 1986; 548 – 592</mixed-citation></citation-alternatives></ref><ref id="cit71"><label>71</label><citation-alternatives><mixed-citation xml:lang="ru">Кольман Я., Рем К.Г. Наглядная биохимия. Мир, М., 2002; 314322.</mixed-citation><mixed-citation xml:lang="en">Кольман Я., Рем К.Г. Наглядная биохимия. Мир, М., 2002; 314322.</mixed-citation></citation-alternatives></ref><ref id="cit72"><label>72</label><citation-alternatives><mixed-citation xml:lang="ru">Боровой С.Г. Дискалиемии. СПбМАПО, СПб., 1997</mixed-citation><mixed-citation xml:lang="en">Боровой С.Г. Дискалиемии. СПбМАПО, СПб., 1997</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
