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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nefr</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology (Saint-Petersburg)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-6274</issn><issn pub-type="epub">2541-9439</issn><publisher><publisher-name>Pavlov First Saint-Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/1561-6274-2004-8-4-25-31</article-id><article-id custom-type="elpub" pub-id-type="custom">nefr-878</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>ДВУЛИКИЙ ЯНУС БИОХИМИИ: МОЧЕВАЯ КИСЛОТА – ОКСИДАНТ ИЛИ АНТИОКСИДАНТ?</article-title><trans-title-group xml:lang="en"><trans-title>THE BIOCHEMICAL IANUS: URIC ACID   OXIDANT OR ANTIOXIDANT?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галунска</surname><given-names>Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Galunskaya</surname><given-names>B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра доклинической и клинической фармакологии и биохимии</p><p>кафедра внутренних болезней, клиника нефрологии и гемодиализа</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Паскалев</surname><given-names>Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Paskalev</surname><given-names>D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра доклинической и клинической фармакологии и биохимии</p><p>кафедра внутренних болезней, клиника нефрологии и гемодиализа</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Янкова</surname><given-names>Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Yankova</surname><given-names>T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра доклинической и клинической фармакологии и биохимии</p><p>кафедра внутренних болезней, клиника нефрологии и гемодиализа</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чанкова</surname><given-names>П.</given-names></name><name name-style="western" xml:lang="en"><surname>Chankova</surname><given-names>P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра доклинической и клинической фармакологии и биохимии</p><p>кафедра внутренних болезней, клиника нефрологии и гемодиализа</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Медицинский университет, университетская больница «Святая Марина»</institution><country>Bulgaria</country></aff><pub-date pub-type="collection"><year>2004</year></pub-date><pub-date pub-type="epub"><day>10</day><month>04</month><year>2004</year></pub-date><volume>8</volume><issue>4</issue><fpage>25</fpage><lpage>31</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Галунска Б., Паскалев Д., Янкова Т., Чанкова П., 2004</copyright-statement><copyright-year>2004</copyright-year><copyright-holder xml:lang="ru">Галунска Б., Паскалев Д., Янкова Т., Чанкова П.</copyright-holder><copyright-holder xml:lang="en">Galunskaya B., Paskalev D., Yankova T., Chankova P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephrolog.ru/jour/article/view/878">https://journal.nephrolog.ru/jour/article/view/878</self-uri><abstract><p>Двуликий Янус биохимии: мочевая кислота – оксидант или антиоксидант?</p></abstract><trans-abstract xml:lang="en"><p>The biochemical Ianus: uric acid oxidant or antioxidant?</p></trans-abstract><kwd-group xml:lang="ru"><kwd>мочевая кислота</kwd><kwd>перекисное окисление</kwd><kwd>окислительный стресс</kwd></kwd-group><kwd-group xml:lang="en"><kwd>uric acid</kwd><kwd>peroxidation</kwd><kwd>oxidation stress</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Spitsin S, Scott G, Kean R et al. 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