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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nefr</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology (Saint-Petersburg)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-6274</issn><issn pub-type="epub">2541-9439</issn><publisher><publisher-name>Pavlov First Saint-Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">nefr-89</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Клинические особенности, качество жизни и прогноз больных с хроническим кардиоренальным синдромом</article-title><trans-title-group xml:lang="en"><trans-title>Clinical characteristics, quality of life and prognosis of patients with chronic cardiorenal syndrome</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ефремова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Efremova</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шутов</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Shutov</surname><given-names>A. M.</given-names></name></name-alternatives><email xlink:type="simple">amshu@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ульяновкий государственный университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ulyanovsk State University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>01</day><month>03</month><year>2015</year></pub-date><volume>19</volume><issue>2</issue><fpage>63</fpage><lpage>67</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ефремова Е.В., Шутов А.М., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Ефремова Е.В., Шутов А.М.</copyright-holder><copyright-holder xml:lang="en">Efremova E.V., Shutov A.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephrolog.ru/jour/article/view/89">https://journal.nephrolog.ru/jour/article/view/89</self-uri><abstract><p>ЦЕЛЬ ИССЛЕДОВАНИЯ: изучить клинические особенности, психологический статус, качество жизни и прогноз больных с хронической сердечной недостаточностью (ХСН) и ХСН в сочетании с хронической болезнью почек (ХБП). ПАЦИЕНТЫ И МЕТОДЫ: обследовано 203 больных (130 мужчин и 73 женщины, средний возраст 61,8±9,6 года) с ХСН. ХСН диагностировали и оценивали в соответствии с Национальными рекомендациями ВНОК и ОССН по диагностике и лечению ХСН (третий пересмотр, 2009). ХБП диагностировали согласно Национальным рекомендациям Научного общества нефрологов России (2012). В группу хронического кардиоренального синдрома (КРС) включали больных с ХСН и ХБП со СКФ&lt;60 мл/мин/1,73 м2. Помимо оценки клинического течения ХСН, числа госпитализаций в течение года наблюдения, была оценена коморбидность по шкале Чарлсона, клинико-психологические особенности и качество жизни (КЖ). РЕЗУЛЬТАТЫ: у 89 (44%) больных диагностирован хронический КРС. Больные с КРС, помимо наличия ХСН и ХБП, имели более высокую коморбидность, чаще повторно госпитализировались в течение года по поводу обострения ХСН по сравнению с больными без КРС. Для больных с КРС характерен более выраженный эмоциональный дискомфорт, наличие депрессивных, дезадаптивных тенденций, снижение КЖ как в физическом, так и в психологическом аспектах. ЗАКЛЮЧЕНИЕ: наличие ХБП негативно сказывается как на клиническом течении больных с ХСН, так и на психологическом статусе. Высокая коморбидность, характерная для данной группы больных, наличие ипохондрических и депрессивных состояний и низкое качество жизни должны учитываться при лечении больных.</p></abstract><trans-abstract xml:lang="en"><p>AIM. The aim of this study was to investigate clinical features, quality of life and prognosis in patients with chronic heart failure (CHF) and patients with CHF associated with chronic kidney disease (CKD). PATIENTS AND METHODS. 203 patients with CHF (130 males and 73 females, mean age was 61,8±9,6 years) were examined. CHF was defined according to the Russian guidelines for the diagnosis and treatment of chronic heart failure, 2012. CKD was defined according to the Russian guidelines for the diagnosis, prevention and treatment of CKD, 2012.Patients with CHF and CKD with GFR &lt;60 mL/min/1,73 m2were included in group of chronic cardiorenal syndrome (CRS). Charlson comorbidity index, duration of hospitalization for a year follow up, clinical and psychological characteristics and quality of life in patients with CHF were estimated. RESULTS. 89 (44%) patients had chronic kidney disease (CKD) with glomerular filtration rate&lt;60mL/min/1,73 m2 (chronic cardiorenal syndrome). Рatients with chronic cardiorenal syndrome had a higher comorbidity. Patients with CRS were hospitalized due to exacerbation CHF for year more often thanpatients without CRS. Рatients with chronic cardiorenal syndrome had expressed emotional discomfort, the presence of depressive, disadaptive trends, decreased of quality of life, both in the physical and the psychological aspects. CONCLUSION. Chronic kidney disease have a negative impact both on the clinical course and quality of life, psychological status and prognosis of patients with CHF. At the same time, patients with CRS have a high comorbidity, they are characterized by the presence of hypochondria and depression and low quality of life, which should be taken into account in the diagnosis and treatment of this group and assessment of prognosis.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая сердечная недостаточность</kwd><kwd>хроническая болезнь почек</kwd><kwd>кардиоренальный синдром</kwd><kwd>коморбидность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Chronic heart failure</kwd><kwd>chronic kidney disease</kwd><kwd>cardiorenal syndrome</kwd><kwd>comorbidity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ronco C., Haapio C., House A.A. et al. Саrdiorenalsyndrome. 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