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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nefr</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology (Saint-Petersburg)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-6274</issn><issn pub-type="epub">2541-9439</issn><publisher><publisher-name>Pavlov First Saint-Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/1561-6274-2003-7-2-67-71</article-id><article-id custom-type="elpub" pub-id-type="custom">nefr-910</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ. КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES. CLINICAL INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>ВЛИЯНИЕ СЕАНСА ГЕМОДИАЛИЗА НА ТРАНСМИТРАЛЬНЫЙ КРОВОТОК</article-title><trans-title-group xml:lang="en"><trans-title>EFFECTS OF A HEMODIALYSIS SESSION ON TRANSMITRAL BLOOD FLOW</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шутов</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Shutov</surname><given-names>A. M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мастыков</surname><given-names>В. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Mastykov</surname><given-names>V. E.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Едигарова</surname><given-names>О. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Edigarova</surname><given-names>O. M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Полетаев</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Poletaev</surname><given-names>I. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Казанков</surname><given-names>Ю. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kazankov</surname><given-names>Yu. N.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Ульяновский государственный университет, Ульяновская областная клиническая больница</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2003</year></pub-date><pub-date pub-type="epub"><day>10</day><month>02</month><year>2003</year></pub-date><volume>7</volume><issue>2</issue><fpage>67</fpage><lpage>71</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шутов А.М., Мастыков В.Э., Едигарова О.М., Полетаев И.В., Казанков Ю.Н., 2003</copyright-statement><copyright-year>2003</copyright-year><copyright-holder xml:lang="ru">Шутов А.М., Мастыков В.Э., Едигарова О.М., Полетаев И.В., Казанков Ю.Н.</copyright-holder><copyright-holder xml:lang="en">Shutov A.M., Mastykov V.E., Edigarova O.M., Poletaev I.V., Kazankov Y.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephrolog.ru/jour/article/view/910">https://journal.nephrolog.ru/jour/article/view/910</self-uri><abstract><p>ЦЕЛЬ РАБОТЫ. Исследовать влияние сеанса гемодиализа (ГД) на трансмитральный кровоток (ТМК). ПАЦИЕНТЫ И МЕТОДЫ. До и после бикарбонатного 4-часового ГД 27 больным (женщин - 15, мужчин - 12; средний возраст 49-12 лет) выполнена эхокардиография, допплерэхокардиография. Определяли максимальные скорости раннего (E) и позднего (А) диастолического наполнения и их отношение (E/A), время изоволюмического расслабления левого желудочка (IVRT), время замедления раннего диастолического потока (DT). До и после гемодиализа определяли концентрацию натрия, калия, кальция, магния в сыворотке крови. РЕЗУЛЬТАТЫ. Гемодиализ привел к снижению максимальной скорости в пике E с 98,3 ±24,8 до 76,5± 23,8 см/с (р&lt;0,001), при этом скорость в пике А существенно не изменилась, снизилось отношение E/A (с 1,21 ±0,59 до 0,95± 0,43; р=0,009). IVRT и DT существенно не изменились. Обнаружена прямая корреляционная связь между величиной ультрафильтрации и динамикой скорости в пике E ( ДЕ, г=0,45; р=0,02). Гемодиализ привел к достоверному снижению калия и натрия и увеличению кальция в сыворотке крови, при этом динамика электролитов не была связана с динамикой параметров ТМК. ЗАКЛЮЧЕНИЕ. Представленные данные свидетельствуют о выраженном влиянии сеанса гемодиализа на диастолическое наполнение левого желудочка. Значительно снижается раннее диастолическое наполнение, что прямо связано с ультрафильтрацией. Больные с величиной ультрафильтрации более 3% массы тела имеют значительно более выраженные изменения трансмитрального кровотока.</p></abstract><trans-abstract xml:lang="en"><p>THEAIM of the work was to investigate the effects of a hemodialysis (HD) session on transmitral blood flow. PATIENTS AND METHODS. Echocargiographyand doppler echocargiography were carried out in 27 patients (15 women and 12 men, average age 49±12 years) before and after bicarbonate 4 hour long HD. Maximum rates of the early (E) and late (A) diastolic filling and their ratio (E/A), time of isovolumic relaxation of the left ventricle (IVRT), time of slowing down the early diastolic flow (DT) were determined. The concentration of sodium, potassium, calcium, magnesium in blood serum were determined before and after HD. RESULTS. Hemodialysis resulted in the reduction of the maximal rate in E peak from 98.3± 24.8 to 76.5±23.8 cm/c (p&lt;0.001), and the rate in A peak did not substantially change, the E/A ratio decreased (from 1.21 ±0.59 to 0.95±0.43; p=0.009). IVRT and DT did not substantially change. A direct correlation relationship was found between the ultrafiltration value and the dynamics of rate in E peak ( D E, r=0.45; p=0.02). Hemodialysis resulted in a reliable decrease of potassium and sodium and increase of calcium in blood serum, the electrolyte dynamics being not associated with the dynamics of the parameters of transmitral blood flow. CONCLUSION. The data obtained suggest a demonstrable influence of a hemodialysis session on the diastolic filling of the left ventricle. The early diastolic filling considerably decreased which had a direct association with ultrafiltration. Patients with the ultrafiltration value more than 3% of the body mass were found to have considerably more demonstrable changes in transmitral blood flow.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гемодиализ</kwd><kwd>допплерэхокардиография</kwd><kwd>трансмитральный кровоток</kwd><kwd>хроническая почечная недостаточность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hemodialysis</kwd><kwd>chronic renal failure</kwd><kwd>doppler echocardiography</kwd><kwd>transmitral blood flow</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Беленков ЮН, Агеев ФТ, Мареев ВЮ. Знакомьтесь: диастолическая Сердечная недостаточность. 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