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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nefr</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology (Saint-Petersburg)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-6274</issn><issn pub-type="epub">2541-9439</issn><publisher><publisher-name>Pavlov First Saint-Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">nefr-94</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Физическое развитие детей с хронической болезнью почек (ХБП)</article-title><trans-title-group xml:lang="en"><trans-title>Physical development in children with chronic kidney disease (CKD)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Настаушева</surname><given-names>Н. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Nastausheva</surname><given-names>N. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стахурлова</surname><given-names>Л. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Stakhurlova</surname><given-names>L. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жданова</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhdanova</surname><given-names>O. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чичуга</surname><given-names>Е. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Chichuga</surname><given-names>E. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Звягина</surname><given-names>Т. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Zvyagina</surname><given-names>T. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Настаушева</surname><given-names>Т. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Nastausheva</surname><given-names>T. L.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Савченко</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Savchenko</surname><given-names>A. P.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Воронежская государственная медицинская академия им. Н.Н. Бурденко<country>Россия</country></aff><aff xml:lang="en">Voronezh State Medical Academy named after N.N. Burdenko<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>01</day><month>05</month><year>2015</year></pub-date><volume>19</volume><issue>3</issue><fpage>32</fpage><lpage>38</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Настаушева Н.С., Стахурлова Л.И., Жданова О.А., Чичуга Е.М., Звягина Т.Г., Настаушева Т.Л., Савченко А.П., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Настаушева Н.С., Стахурлова Л.И., Жданова О.А., Чичуга Е.М., Звягина Т.Г., Настаушева Т.Л., Савченко А.П.</copyright-holder><copyright-holder xml:lang="en">Nastausheva N.S., Stakhurlova L.I., Zhdanova O.A., Chichuga E.M., Zvyagina T.G., Nastausheva T.L., Savchenko A.P.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephrolog.ru/jour/article/view/94">https://journal.nephrolog.ru/jour/article/view/94</self-uri><abstract><p>Отклонения в физическом развитии у детей являются ранними диагностическими и прогностическими критериями при различных заболеваниях, в частности, при хронической болезни почек (ХБП). Для сравнительной оценки полученных данных могут быть использованы стандарты нормального физического развития детей, разработанные Всемирной организацией здравоохранения (ВОЗ) в 1997-2003 годах с использованием жестких стандартных подходов к выборке детей или региональные справочные нормативные материалы. Рост детей с ХБП часто значительно ниже по сравнению с общей детской популяцией. Данные по массе тела у детей с ХБП разноречивы, при гломерулярных заболеваниях чаще выявляются избыток массы тела и ожирение. На рост детей при ХБП влияют: этиология заболевания почек, приведшая к ХБП, возраст начала заболевания почек, метаболический ацидоз, функция почек, некоторые генетические факторы и факторы внутриутробного развития. Поэтому необходима терапия, направленная на компенсацию ацидоза, замедляющая снижение функции почек, а при тяжелом дефиците роста - терапия гормоном роста. Нарушения в физическом развитии детей с ХБП необходимо определять как можно раньше для проведения более ранней коррекции физического развития больных. Важным является определение прогностических критериев для физического развития детей и подростков с ХБП, включая но только признаки заболевания, но и генетические показатели, а также показатели внутриутробного развития.</p></abstract><trans-abstract xml:lang="en"><p>The disturbances of physical development in children are early diagnostic and prognostic markers in different diseases, for example in chronic kidney disease (CKD). For comparative evaluation can be used standards of normal physical development in children designed by World Health Organization (WHO) using hard standardized approaches in 1997-2003 years, or regional reference charts. Height of children with CKD Severe growth impairment is significantly below than in general pediatric population. The results of the weight in children with CKD are contradictory, in glomerular diseases patients often have overweight and obese. Following factors can influence over height in children with CKD: etiology of nephropathies, which leaded to CKD, age at CKD onset, metabolic acidosis, kidney function, some genetic factors and intrauterine development factors. Therefore, the patients need treatment directed at acidosis compensation, inhibiting nephratonia, and at severe growth deficiency - growth hormon therapy. The disturbances of physical development in children with CKD should be determined as soon as possible to provide early correction of physical development in patients. It is important to define the prognostic factors for physical development in children and adolescents with CKD, including not only disease signs but also genetic and intrauterine factors.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>физическое развитие</kwd><kwd>рост</kwd><kwd>масса тела</kwd><kwd>хроническая болезнь почек</kwd></kwd-group><kwd-group xml:lang="en"><kwd>physical growth</kwd><kwd>height</kwd><kwd>weight</kwd><kwd>chronic kidney disease</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Баранов А.А., Кучма В.Р., Сухарева Л.М. и др. Универсальная оценка физического развития младших школьников. Пособие для медицинских работников. РОШУМЗ, М., 2010; 5, 9-10 [Baranov A.A., Kuchma V.R., Suhareva L.M. i dr. Universal'naia ocenka fizicheskogo razvitiia mladshikh shkol'nikov. Posobie dlia meditcinskikh rabotneykov. 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