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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nefr</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology (Saint-Petersburg)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-6274</issn><issn pub-type="epub">2541-9439</issn><publisher><publisher-name>Pavlov First Saint-Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/1561-6274-2007-11-4-28-46</article-id><article-id custom-type="elpub" pub-id-type="custom">nefr-948</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>ОСОБЕННОСТИ  ФУНКЦИИ  ЭНДОТЕЛИЯ  ПРИ  ХРОНИЧЕСКОЙ  БОЛЕЗНИ  ПОЧЕК.  ОБЗОР ЛИТЕРАТУРЫ  И  СОБСТВЕННЫЕ ДАННЫЕ</article-title><trans-title-group xml:lang="en"><trans-title>SPECIFIC  FUNCTIONS OF THE  ENDOTHELIUM  IN  CHRONIC  KIDNEY  DISEASE.  LITERATURE  REVIEW AND  PERSONAL DATA</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Панина</surname><given-names>И. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Panina</surname><given-names>I. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра пропедевтики внутренних болезней, </p><p>Научно-исследовательский  институт нефрологии, кафедра патофизиологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Румянцев</surname><given-names>А. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Rumyantsev</surname><given-names>A. Sh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра пропедевтики внутренних болезней, </p><p>Научно-исследовательский  институт нефрологии, кафедра патофизиологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Меншутина</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Menshutina</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра пропедевтики внутренних болезней, </p><p>Научно-исследовательский институт нефрологии, кафедра патофизиологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ачкасова</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Achkasova</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра пропедевтики внутренних болезней, </p><p>Научно-исследовательский  институт нефрологии, кафедра патофизиологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дегтерева</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Degtereva</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра пропедевтики внутренних болезней,</p><p>Научно-исследовательский институт нефрологии, кафедра патофизиологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тугушева</surname><given-names>Ф. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Tugusheva</surname><given-names>F. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра пропедевтики внутренних болезней, </p><p>Научно-исследовательский институт нефрологии, кафедра патофизиологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зубин</surname><given-names>И. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Zubina</surname><given-names>I. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра пропедевтики внутренних болезней, </p><p>Научно-исследовательский институт нефрологии, кафедра патофизиологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Санкт-Петербургский государственный медицинский университет им. акад.  И.П. Павлова</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2007</year></pub-date><pub-date pub-type="epub"><day>10</day><month>04</month><year>2007</year></pub-date><volume>11</volume><issue>4</issue><fpage>28</fpage><lpage>46</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Панина И.Ю., Румянцев А.Ш., Меншутина М.А., Ачкасова В.В., Дегтерева О.А., Тугушева Ф.А., Зубин И.М., 2007</copyright-statement><copyright-year>2007</copyright-year><copyright-holder xml:lang="ru">Панина И.Ю., Румянцев А.Ш., Меншутина М.А., Ачкасова В.В., Дегтерева О.А., Тугушева Ф.А., Зубин И.М.</copyright-holder><copyright-holder xml:lang="en">Panina I.Y., Rumyantsev A.S., Menshutina M.A., Achkasova V.V., Degtereva O.A., Tugusheva F.A., Zubina I.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephrolog.ru/jour/article/view/948">https://journal.nephrolog.ru/jour/article/view/948</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая болезнь почек</kwd><kwd>сердечно-сосудистые осложнения</kwd><kwd>эндотелий</kwd><kwd>эндотелиальная дисфункция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic kidney disease</kwd><kwd>cardio-vascular complications</kwd><kwd>endothelium</kwd><kwd>endothelial dysfunction</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Davies MJ, Thomas АС. Plaque fissuring – the cause of acute myocardial infarction, sudden ischemic death, and creshendo angina. Brit Heart Jourrn 1985; 53: 363-373</mixed-citation><mixed-citation xml:lang="en">Davies MJ, Thomas АС. Plaque fissuring – the cause of acute myocardial infarction, sudden ischemic death, and creshendo angina. Brit Heart Jourrn 1985; 53: 363-373</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Fuster V, Lewis A. Mechanisms leading to myocardial infarction: Insights from studies of vascular biology. Circulation 1994; 90: 2126-2146</mixed-citation><mixed-citation xml:lang="en">Fuster V, Lewis A. Mechanisms leading to myocardial infarction: Insights from studies of vascular biology. Circulation 1994; 90: 2126-2146</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Falk E, Shah PK, Faster V. Coronary plaque disruption. Circulation 1995; 92: 657-671</mixed-citation><mixed-citation xml:lang="en">Falk E, Shah PK, Faster V. Coronary plaque disruption. Circulation 1995; 92: 657-671</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Петрищев НН. Современные аспекты эндотелиопротекции в клинической практике. Ангиопротекция в практике терапевта: Материалы III Конгресса терапевтов Санкт-Петербурга и Северо-Западного Федерального округа России. СПб., 2004; 3-6</mixed-citation><mixed-citation xml:lang="en">Петрищев НН. Современные аспекты эндотелиопротекции в клинической практике. Ангиопротекция в практике терапевта: Материалы III Конгресса терапевтов Санкт-Петербурга и Северо-Западного Федерального округа России. СПб., 2004; 3-6</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Петрищев НН, Власов ТД. Физиология и патофизиология эндотелия. В: Петрищев НН, ред. Дисфункция эндотелия. Причины, механизмы, фармакологическая коррекция.Изд-во СПбГМУ, СПб., 2003; 4-38</mixed-citation><mixed-citation xml:lang="en">Петрищев НН, Власов ТД. Физиология и патофизиология эндотелия. В: Петрищев НН, ред. Дисфункция эндотелия. Причины, механизмы, фармакологическая коррекция.Изд-во СПбГМУ, СПб., 2003; 4-38</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Britten MB, Zeiher AM, Schachinger V. Clinical importance of coronary endothelial vasodilator dysfunction and therapeutic options. J Intern Med 1999; 245(4): 315-321</mixed-citation><mixed-citation xml:lang="en">Britten MB, Zeiher AM, Schachinger V. Clinical importance of coronary endothelial vasodilator dysfunction and therapeutic options. J Intern Med 1999; 245(4): 315-321</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Шишкин АН, Кирилюк ДВ. Дисфункция эндотелия у пациентов с прогрессирующими заболеваниями почек. Нефрология 2005; 9(2): 16-22</mixed-citation><mixed-citation xml:lang="en">Шишкин АН, Кирилюк ДВ. Дисфункция эндотелия у пациентов с прогрессирующими заболеваниями почек. Нефрология 2005; 9(2): 16-22</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Noguera A, Busquets X, Sauleda J et al. Expression of adhesion molecules and G proteins in circulating neut trophils in chronic pulmonary disease. Am J Crit Care Med 1998; 158(5): 1664-1668</mixed-citation><mixed-citation xml:lang="en">Noguera A, Busquets X, Sauleda J et al. Expression of adhesion molecules and G proteins in circulating neut trophils in chronic pulmonary disease. Am J Crit Care Med 1998; 158(5): 1664-1668</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Гомазков ОА. Пептиды в кардиологии. Биохимия. Физиология. Патология. Информация. Анализ. Материк Альфа, М., 2000; 143</mixed-citation><mixed-citation xml:lang="en">Гомазков ОА. Пептиды в кардиологии. Биохимия. Физиология. Патология. Информация. Анализ. Материк Альфа, М., 2000; 143</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Дедов ИИ, Шестакова МВ, Кочемасова ТВ и др. Дисфункция эндотелия в развитии сосудистых осложнений сахарного диабета. Рос физиол журн им И.М. Сеченова 2001; 87(8): 1073-1084</mixed-citation><mixed-citation xml:lang="en">Дедов ИИ, Шестакова МВ, Кочемасова ТВ и др. Дисфункция эндотелия в развитии сосудистых осложнений сахарного диабета. Рос физиол журн им И.М. Сеченова 2001; 87(8): 1073-1084</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Shirahase H, Fujiwara M, Usui H, Kurahashi K. A possible role of thromboxane A2 in endothelium in maintaining resting tone and producing contractile response to acetylcholine and arachidonic acid in canine cerebral artery. Blood Vessels 1987; 24: 117-119</mixed-citation><mixed-citation xml:lang="en">Shirahase H, Fujiwara M, Usui H, Kurahashi K. A possible role of thromboxane A2 in endothelium in maintaining resting tone and producing contractile response to acetylcholine and arachidonic acid in canine cerebral artery. Blood Vessels 1987; 24: 117-119</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Kato T, Iwama Y, Okumura K et al. Prostaglandin H2 may be the endothelium-derived contracting factor released by acetylcholine in the aorta of the rat. Hypertension 1990; 15: 475-482</mixed-citation><mixed-citation xml:lang="en">Kato T, Iwama Y, Okumura K et al. Prostaglandin H2 may be the endothelium-derived contracting factor released by acetylcholine in the aorta of the rat. Hypertension 1990; 15: 475-482</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Marie I, Beny JL. Endothelial dysfunction in murine model of systemic sclerosis. J Invest Dermatol 2002; 119(6): 1379-1385</mixed-citation><mixed-citation xml:lang="en">Marie I, Beny JL. Endothelial dysfunction in murine model of systemic sclerosis. J Invest Dermatol 2002; 119(6): 1379-1385</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Cannon RO. Role of nitric oxide in cardiovascular disease: focus on the endothelium. Clin Chem 1998; 44: 1809-1819</mixed-citation><mixed-citation xml:lang="en">Cannon RO. Role of nitric oxide in cardiovascular disease: focus on the endothelium. Clin Chem 1998; 44: 1809-1819</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Forstermann U, Biossel JP, Kleinert H. Expressional control of the constitutive isofiorms of nitric oxide synthase (NOS I and NOS III). FASEB J 1998; 12: 773-790</mixed-citation><mixed-citation xml:lang="en">Forstermann U, Biossel JP, Kleinert H. Expressional control of the constitutive isofiorms of nitric oxide synthase (NOS I and NOS III). FASEB J 1998; 12: 773-790</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Li H., Forstermann U. Nitric oxide in the pathogenesis of vascular disease. J Pathol 2000; 90: 244-254</mixed-citation><mixed-citation xml:lang="en">Li H., Forstermann U. Nitric oxide in the pathogenesis of vascular disease. J Pathol 2000; 90: 244-254</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Sessa WC. The nitric oxide synthase family of proteins. J Vasc Res 1994; 31: 131-143</mixed-citation><mixed-citation xml:lang="en">Sessa WC. The nitric oxide synthase family of proteins. J Vasc Res 1994; 31: 131-143</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Манухина ЕБ, Смирин БВ, Малышев ИЮ и др. Депонирование оксида азота в сердечно-сосудистой системе. Известия РАН. Серия биологическая 2002; 3</mixed-citation><mixed-citation xml:lang="en">Манухина ЕБ, Смирин БВ, Малышев ИЮ и др. Депонирование оксида азота в сердечно-сосудистой системе. Известия РАН. Серия биологическая 2002; 3</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Onda Т, Mashiko S, Hamano M et al. Enhancement of endothelium-dependent relaxation in the aorta from stroke-prone spontaneously hypertensive rats at developmental stages of hypertension. Clin Exp Pharm Physiol 1994; 2i: 857-863</mixed-citation><mixed-citation xml:lang="en">Onda Т, Mashiko S, Hamano M et al. Enhancement of endothelium-dependent relaxation in the aorta from stroke-prone spontaneously hypertensive rats at developmental stages of hypertension. Clin Exp Pharm Physiol 1994; 2i: 857-863</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Liischer TF. The endothelium in hypertension: bystander, target or mediator? J Hypertens1994; 12 [suppl 10]: S105-S116</mixed-citation><mixed-citation xml:lang="en">Liischer TF. The endothelium in hypertension: bystander, target or mediator? J Hypertens1994; 12 [suppl 10]: S105-S116</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Wever RMF, Liischer TF, Consentino F et al. Atherosclerosis and the two faces of endothelial nitric oxide synthase. Circulation 1998; 97: 108-112</mixed-citation><mixed-citation xml:lang="en">Wever RMF, Liischer TF, Consentino F et al. Atherosclerosis and the two faces of endothelial nitric oxide synthase. Circulation 1998; 97: 108-112</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Muijsers RBR, Folkets G, Henricks PAJ et al. Peroxynitrite: a two-faced metabolite of nitric oxide. Life Sci 1997; 60: 1833-1845</mixed-citation><mixed-citation xml:lang="en">Muijsers RBR, Folkets G, Henricks PAJ et al. Peroxynitrite: a two-faced metabolite of nitric oxide. Life Sci 1997; 60: 1833-1845</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Ванин АФ, Манухина ЕБ, Лапшин АВ, Меерсон ФЗ. Усиление синтеза оксида азота в стенке аорты при экспериментальном инфаркте миокарда. Бюл экспер биол 1993; 116(8): 142-144</mixed-citation><mixed-citation xml:lang="en">Ванин АФ, Манухина ЕБ, Лапшин АВ, Меерсон ФЗ. Усиление синтеза оксида азота в стенке аорты при экспериментальном инфаркте миокарда. Бюл экспер биол 1993; 116(8): 142-144</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Манухина ЕБ, Покидышев ДА, Маленюк ЕБ и др. Защитный эффект окиси азота при тепловом шоке. Известия РАН. Серия биологическая 1997; 1: 54-58</mixed-citation><mixed-citation xml:lang="en">Манухина ЕБ, Покидышев ДА, Маленюк ЕБ и др. Защитный эффект окиси азота при тепловом шоке. Известия РАН. Серия биологическая 1997; 1: 54-58</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Стокле Ж-К, Мюлле Б, Андрианцитохайна Р, Клещев А. Гиперпродукция оксида азота в патофизиологии кровеносных сосудов. Биохимия 1998; 63 (7): 976-983</mixed-citation><mixed-citation xml:lang="en">Стокле Ж-К, Мюлле Б, Андрианцитохайна Р, Клещев А. Гиперпродукция оксида азота в патофизиологии кровеносных сосудов. Биохимия 1998; 63 (7): 976-983</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Star RA. Nitric oxide: Southwestern Internal Medicine Conference. Am J Med Soc 1993; 306: 348-355</mixed-citation><mixed-citation xml:lang="en">Star RA. Nitric oxide: Southwestern Internal Medicine Conference. Am J Med Soc 1993; 306: 348-355</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Koch MA, Hasser EM, Schadt JC. Influence of nitric oxide on the hemodynamic response to hemorrhage in conscious rabbits. Am J Physiol 1995; 37: R171-R182</mixed-citation><mixed-citation xml:lang="en">Koch MA, Hasser EM, Schadt JC. Influence of nitric oxide on the hemodynamic response to hemorrhage in conscious rabbits. Am J Physiol 1995; 37: R171-R182</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Mitsuhara H, Takeuchi H, Saitoh J et al. An inhibitor of nitric oxide synthase, N(omega)-nitro-L-arginine-methyl ester, attenuates hypotension but does not improve cardiac depression in anaphylaxis in dogs. Shock 1995; 3: 447-453</mixed-citation><mixed-citation xml:lang="en">Mitsuhara H, Takeuchi H, Saitoh J et al. An inhibitor of nitric oxide synthase, N(omega)-nitro-L-arginine-methyl ester, attenuates hypotension but does not improve cardiac depression in anaphylaxis in dogs. Shock 1995; 3: 447-453</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Arnal J-F, Dinh-Xuan A-T, Pueyo M et al. Endothelium-derived nitric oxide and vascular physiology. Cell Mol Life 1999; 55: 1078-1087</mixed-citation><mixed-citation xml:lang="en">Arnal J-F, Dinh-Xuan A-T, Pueyo M et al. Endothelium-derived nitric oxide and vascular physiology. Cell Mol Life 1999; 55: 1078-1087</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Abrahamsson Т, Brandt U, Marklund SL et al. Vascular bound recombinant extracellular superoxide dismutase type С protect against the detrimental effects of superoxide radicals on endothelium-dependent arterial relaxation. Circulat Res 1992; 70: 264-271</mixed-citation><mixed-citation xml:lang="en">Abrahamsson Т, Brandt U, Marklund SL et al. Vascular bound recombinant extracellular superoxide dismutase type С protect against the detrimental effects of superoxide radicals on endothelium-dependent arterial relaxation. Circulat Res 1992; 70: 264-271</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Pagano PJ, Tornheim K, Cohen RA. Superoxide anion production by the rabbit thoracic aorta: Effect of endothelium-derived nitric oxide. Am J Physiol 1993; 265: H707-H712</mixed-citation><mixed-citation xml:lang="en">Pagano PJ, Tornheim K, Cohen RA. Superoxide anion production by the rabbit thoracic aorta: Effect of endothelium-derived nitric oxide. Am J Physiol 1993; 265: H707-H712</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Cohen RA. The role of nitric oxide and other endothelium-derived vasoactive substances in vascular disease. Progr Cardio-Vasc Dis I995; 38: 105-128</mixed-citation><mixed-citation xml:lang="en">Cohen RA. The role of nitric oxide and other endothelium-derived vasoactive substances in vascular disease. Progr Cardio-Vasc Dis I995; 38: 105-128</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Feliciano L, Henning RJ. Coronary artery blood flow: physiologic and pathophysiologic regulation. Clin Cardiol 1999; 22: 775-786</mixed-citation><mixed-citation xml:lang="en">Feliciano L, Henning RJ. Coronary artery blood flow: physiologic and pathophysiologic regulation. Clin Cardiol 1999; 22: 775-786</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Galle J, Bauersachs J, Bassenge E, Busse R. Arterial size determines the enhancement of contractile responses after suppression of endothelium-derived relaxing factor formation. Pflugers Arch 1993; 422: 564-569</mixed-citation><mixed-citation xml:lang="en">Galle J, Bauersachs J, Bassenge E, Busse R. Arterial size determines the enhancement of contractile responses after suppression of endothelium-derived relaxing factor formation. Pflugers Arch 1993; 422: 564-569</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Lozano G, Pagliaro P, Gatullo D, Marsh NA. Control of coronary blood flow by endothelial release of nitric oxide. Clin Exp Pharmacol Physiol 1994; 21: 783-789</mixed-citation><mixed-citation xml:lang="en">Lozano G, Pagliaro P, Gatullo D, Marsh NA. Control of coronary blood flow by endothelial release of nitric oxide. Clin Exp Pharmacol Physiol 1994; 21: 783-789</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Levin ER. Endothelins. N Engl J Med 1995; 323: 356-363</mixed-citation><mixed-citation xml:lang="en">Levin ER. Endothelins. N Engl J Med 1995; 323: 356-363</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Schwarz P, Diem R, Dun NJ, Forstermann U. Endogenous and exogenous nitric oxide inhibits norepinephrine release from rat heart synpathetic nerves. Circulat Res 1995; 77: 841-848</mixed-citation><mixed-citation xml:lang="en">Schwarz P, Diem R, Dun NJ, Forstermann U. Endogenous and exogenous nitric oxide inhibits norepinephrine release from rat heart synpathetic nerves. Circulat Res 1995; 77: 841-848</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Hare J, Colluci WS. Role of nitric oxide in the regulation of myocardial function. Progr Cardiovasc Res 1995; 28: 155-166</mixed-citation><mixed-citation xml:lang="en">Hare J, Colluci WS. Role of nitric oxide in the regulation of myocardial function. Progr Cardiovasc Res 1995; 28: 155-166</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Lewis MJ, Shah AM. Endothelial modulation of myocardial contraction. Endothelium 1994; 1: 237-243</mixed-citation><mixed-citation xml:lang="en">Lewis MJ, Shah AM. Endothelial modulation of myocardial contraction. Endothelium 1994; 1: 237-243</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Welch G, Loscalzo J. Nitric oxide and cardiovascular system. J Cardiovasc Surg1994; 9: 361-371</mixed-citation><mixed-citation xml:lang="en">Welch G, Loscalzo J. Nitric oxide and cardiovascular system. J Cardiovasc Surg1994; 9: 361-371</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Jeremy JY, Rowe D, Emsley AM, Newby AC. Nitric oxide and the proliferation of vascular smooth muscle cells. Cardiovasc Res 1999; 43: 580-594</mixed-citation><mixed-citation xml:lang="en">Jeremy JY, Rowe D, Emsley AM, Newby AC. Nitric oxide and the proliferation of vascular smooth muscle cells. Cardiovasc Res 1999; 43: 580-594</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Han X, Shimoni Y, Giles WR. An obligatory role for nitric oxide in autonomic control of mammalian heart rate. J Physiol 1994; 476: 309-314</mixed-citation><mixed-citation xml:lang="en">Han X, Shimoni Y, Giles WR. An obligatory role for nitric oxide in autonomic control of mammalian heart rate. J Physiol 1994; 476: 309-314</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Minami N, Imai Y, Nishiyama H, Abe K. Role of nitric oxide in the development of vascular α1-adrenoreceptor desensitization and pressure diuresis in conscious rats. Hypertension 1997; 29: 969-975</mixed-citation><mixed-citation xml:lang="en">Minami N, Imai Y, Nishiyama H, Abe K. Role of nitric oxide in the development of vascular α1-adrenoreceptor desensitization and pressure diuresis in conscious rats. Hypertension 1997; 29: 969-975</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Tolins IP, Raij R. Role of endothelium-derived relaxing factor in hemodynamic response to acetylcholine in vivo. In: Nitric oxide from L-arginin: a bioregulatory system. Royal Society, London, 1989; 13</mixed-citation><mixed-citation xml:lang="en">Tolins IP, Raij R. Role of endothelium-derived relaxing factor in hemodynamic response to acetylcholine in vivo. In: Nitric oxide from L-arginin: a bioregulatory system. Royal Society, London, 1989; 13</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Thiemerman C, Vane J. Inhibition of nitric oxide synthesis reduces the hypotension induced by bacterial lypopolysaccharides in the rat in vivo. Eur J Pharmacol 1990; 182: 591-595</mixed-citation><mixed-citation xml:lang="en">Thiemerman C, Vane J. Inhibition of nitric oxide synthesis reduces the hypotension induced by bacterial lypopolysaccharides in the rat in vivo. Eur J Pharmacol 1990; 182: 591-595</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Gardiner SM, Compton AM, Bennett T et al. Control of regional blood flow by endothelium-derived nitric oxide. Hypertension 1990; 15: 486-492</mixed-citation><mixed-citation xml:lang="en">Gardiner SM, Compton AM, Bennett T et al. Control of regional blood flow by endothelium-derived nitric oxide. Hypertension 1990; 15: 486-492</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Zatz R, Baylis С. Chronic nitric oxide inhibition model six years on. Hypertension 1998; 32: 958-964</mixed-citation><mixed-citation xml:lang="en">Zatz R, Baylis С. Chronic nitric oxide inhibition model six years on. Hypertension 1998; 32: 958-964</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Gerova M. Nitric oxide compromised hypertension: facts and enigmas. Physiol Res 2000; 49: 27-35</mixed-citation><mixed-citation xml:lang="en">Gerova M. Nitric oxide compromised hypertension: facts and enigmas. Physiol Res 2000; 49: 27-35</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Baylis C, Mitruka В, Deng A. Chronic blockade of nitric oxide synthesis in the rat produced systemic hypertension and glomerular damage. J Clin Invest 1992; 90: 278-281</mixed-citation><mixed-citation xml:lang="en">Baylis C, Mitruka В, Deng A. Chronic blockade of nitric oxide synthesis in the rat produced systemic hypertension and glomerular damage. J Clin Invest 1992; 90: 278-281</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Chatziantoniou C, Boffa J, Ardaillou R, Dussaule J. Nitric oxide inhibition and early activation of type I collagen gene in renal resistance vessels and glomeruli in transgenic mice. J Clin Invest 1998; 101: 2780-2789</mixed-citation><mixed-citation xml:lang="en">Chatziantoniou C, Boffa J, Ardaillou R, Dussaule J. Nitric oxide inhibition and early activation of type I collagen gene in renal resistance vessels and glomeruli in transgenic mice. J Clin Invest 1998; 101: 2780-2789</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Sessa WC, Pritchard K, Seyedi N et al. Chronic exercise in dog increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression. Circulat Res 1994; 74: 349-353</mixed-citation><mixed-citation xml:lang="en">Sessa WC, Pritchard K, Seyedi N et al. Chronic exercise in dog increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression. Circulat Res 1994; 74: 349-353</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Koller A, Kaley G. Shear stress dependent regulation of vascular resistance in health and disease: role of endothelium. Endothelium 1996; 4: 247-272</mixed-citation><mixed-citation xml:lang="en">Koller A, Kaley G. Shear stress dependent regulation of vascular resistance in health and disease: role of endothelium. Endothelium 1996; 4: 247-272</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Celermajer DS, Sorensen KE, Gooch VM et al. Noninvasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet 1992; 340: 1111-1115</mixed-citation><mixed-citation xml:lang="en">Celermajer DS, Sorensen KE, Gooch VM et al. Noninvasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet 1992; 340: 1111-1115</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Panza JA, Casino PR, Kilcoyne СМ, Quyyumi AA. Role of endothelium-derived nitric oxide in the abnormal endothelium-dependent vascular relaxation of patients with essential hypertension. Circulation1993; 87: 1468-1474</mixed-citation><mixed-citation xml:lang="en">Panza JA, Casino PR, Kilcoyne СМ, Quyyumi AA. Role of endothelium-derived nitric oxide in the abnormal endothelium-dependent vascular relaxation of patients with essential hypertension. Circulation1993; 87: 1468-1474</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Antony I, Lerebours G, Nitemberg A. Loss of flow-dependent coronary artery dilatation in patients with hypertension. Circulation 1995; 91: 1624-1628</mixed-citation><mixed-citation xml:lang="en">Antony I, Lerebours G, Nitemberg A. Loss of flow-dependent coronary artery dilatation in patients with hypertension. Circulation 1995; 91: 1624-1628</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Lind L, Sarabi M, Millgard J. Methodological aspects of the evaluation of endothelium-dependent vasodilatation in the human forearm. Clin Physiol 1998; 18: 81-87</mixed-citation><mixed-citation xml:lang="en">Lind L, Sarabi M, Millgard J. Methodological aspects of the evaluation of endothelium-dependent vasodilatation in the human forearm. Clin Physiol 1998; 18: 81-87</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Egashira K, Suzuki S, Hirooka Y et al. Impaired endothelium-dependent vasodilation of large epicardial and resistance coronary arteries in patients with essential hypertension. Hypertension 1995; 25: 201-206</mixed-citation><mixed-citation xml:lang="en">Egashira K, Suzuki S, Hirooka Y et al. Impaired endothelium-dependent vasodilation of large epicardial and resistance coronary arteries in patients with essential hypertension. Hypertension 1995; 25: 201-206</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Panza JA, Quyyumi AA, Brush JEJr, Epstein SE. Abnormal endothelium-dependent relaxation in patients with essential hypertension. N Engl J Med 1990; 323: 22-27</mixed-citation><mixed-citation xml:lang="en">Panza JA, Quyyumi AA, Brush JEJr, Epstein SE. Abnormal endothelium-dependent relaxation in patients with essential hypertension. N Engl J Med 1990; 323: 22-27</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Anderson WD, Klein JL, Manoukian SV. Coronary flow mediated dilation is preserved in hypertensive patients. J Am Coc Cardiol 1994; 23: 107A</mixed-citation><mixed-citation xml:lang="en">Anderson WD, Klein JL, Manoukian SV. Coronary flow mediated dilation is preserved in hypertensive patients. J Am Coc Cardiol 1994; 23: 107A</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Minor RI, Myers PR, Guerra R Jr et al. Diet-induced atherosclerosis increases the release of nitrogen oxides from rabbit aorta.J Clin Invest 1990; 86: 2109-2116</mixed-citation><mixed-citation xml:lang="en">Minor RI, Myers PR, Guerra R Jr et al. Diet-induced atherosclerosis increases the release of nitrogen oxides from rabbit aorta.J Clin Invest 1990; 86: 2109-2116</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">Drexler H, Zeiher AM, Meinzer K, Just H. Correction of endothelial dysfunction in coronary microcirculation of hyper-cholesterolemic patients by L-arginine. Lancet 1991; 338: 1546-1550</mixed-citation><mixed-citation xml:lang="en">Drexler H, Zeiher AM, Meinzer K, Just H. Correction of endothelial dysfunction in coronary microcirculation of hyper-cholesterolemic patients by L-arginine. Lancet 1991; 338: 1546-1550</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Cardillo C, Kilcoyne СМ, Quyyumi AA et al. Selective defect in nitric oxide synthesis may explain the impaired endothelium-dependent vasodilatation in patients with essential hypertension. Circulation 1998; 97: 851-856</mixed-citation><mixed-citation xml:lang="en">Cardillo C, Kilcoyne СМ, Quyyumi AA et al. Selective defect in nitric oxide synthesis may explain the impaired endothelium-dependent vasodilatation in patients with essential hypertension. Circulation 1998; 97: 851-856</mixed-citation></citation-alternatives></ref><ref id="cit63"><label>63</label><citation-alternatives><mixed-citation xml:lang="ru">Rudic RD, Sessa WC. Nitric oxide in endothelial dysfunction and vascular remodeling: Clinical correlates and experimental links. Am J Hum Genet 1999; 64: 673-677</mixed-citation><mixed-citation xml:lang="en">Rudic RD, Sessa WC. Nitric oxide in endothelial dysfunction and vascular remodeling: Clinical correlates and experimental links. Am J Hum Genet 1999; 64: 673-677</mixed-citation></citation-alternatives></ref><ref id="cit64"><label>64</label><citation-alternatives><mixed-citation xml:lang="ru">Birnbaum Y, Fishbein MC, Luo H et al. Regional remodeling of atherosclerotic arteries: a major determinant of clinical manifestations of disease. J Am Coll Cardiol 1997; 30: 1149-1164</mixed-citation><mixed-citation xml:lang="en">Birnbaum Y, Fishbein MC, Luo H et al. Regional remodeling of atherosclerotic arteries: a major determinant of clinical manifestations of disease. J Am Coll Cardiol 1997; 30: 1149-1164</mixed-citation></citation-alternatives></ref><ref id="cit65"><label>65</label><citation-alternatives><mixed-citation xml:lang="ru">Nimaguchi K, Egashira K, Takemoto M et al. Chronic inhibition of nitric oxide synthesis causes coronary microvascular remodeling in rats. Hypertension 1995; 26: 957-962</mixed-citation><mixed-citation xml:lang="en">Nimaguchi K, Egashira K, Takemoto M et al. Chronic inhibition of nitric oxide synthesis causes coronary microvascular remodeling in rats. Hypertension 1995; 26: 957-962</mixed-citation></citation-alternatives></ref><ref id="cit66"><label>66</label><citation-alternatives><mixed-citation xml:lang="ru">Luvara G, Pueyo M, Philippe M et al. Chronic blockade of NO synthase activity induces a proinflammatory phenotype in the arterial wall: prevention by angiotensin II antagonism. Arterioscler Thromb Vasc Biol 1998; 18: 1408-1416</mixed-citation><mixed-citation xml:lang="en">Luvara G, Pueyo M, Philippe M et al. Chronic blockade of NO synthase activity induces a proinflammatory phenotype in the arterial wall: prevention by angiotensin II antagonism. Arterioscler Thromb Vasc Biol 1998; 18: 1408-1416</mixed-citation></citation-alternatives></ref><ref id="cit67"><label>67</label><citation-alternatives><mixed-citation xml:lang="ru">Godecke A, Decking UK, Ding Z et al. Coronary hemodynamics in endothelial NO synthase knockout mice. Circulat Res 1998; 82: 186-194</mixed-citation><mixed-citation xml:lang="en">Godecke A, Decking UK, Ding Z et al. Coronary hemodynamics in endothelial NO synthase knockout mice. Circulat Res 1998; 82: 186-194</mixed-citation></citation-alternatives></ref><ref id="cit68"><label>68</label><citation-alternatives><mixed-citation xml:lang="ru">Huang PL, Huang Z, Mashimo H et al Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature 1995; 377: 239-242</mixed-citation><mixed-citation xml:lang="en">Huang PL, Huang Z, Mashimo H et al Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature 1995; 377: 239-242</mixed-citation></citation-alternatives></ref><ref id="cit69"><label>69</label><citation-alternatives><mixed-citation xml:lang="ru">Moroi M, Zhang L, Yasuda T et al. Interaction of genetic deficiency of endothelial nitric oxide, gender, and pregnancy in vascular response to injury in mice. J Clin Invest 1998; 101: 1225-1232</mixed-citation><mixed-citation xml:lang="en">Moroi M, Zhang L, Yasuda T et al. Interaction of genetic deficiency of endothelial nitric oxide, gender, and pregnancy in vascular response to injury in mice. J Clin Invest 1998; 101: 1225-1232</mixed-citation></citation-alternatives></ref><ref id="cit70"><label>70</label><citation-alternatives><mixed-citation xml:lang="ru">Papapetropoulos A, Garcia-Cardena G, Madri JA, Sessa WC. Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells. J Clin Invest 1997; 100: 3131-3139</mixed-citation><mixed-citation xml:lang="en">Papapetropoulos A, Garcia-Cardena G, Madri JA, Sessa WC. Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells. J Clin Invest 1997; 100: 3131-3139</mixed-citation></citation-alternatives></ref><ref id="cit71"><label>71</label><citation-alternatives><mixed-citation xml:lang="ru">Meeus F, Kourilsky O, Guerin AP et al. Pathophysiology of cardiovascular disease in hemodialysis patients. Kidney Int 2000; 58 [suppl 76]: 140-146</mixed-citation><mixed-citation xml:lang="en">Meeus F, Kourilsky O, Guerin AP et al. Pathophysiology of cardiovascular disease in hemodialysis patients. Kidney Int 2000; 58 [suppl 76]: 140-146</mixed-citation></citation-alternatives></ref><ref id="cit72"><label>72</label><citation-alternatives><mixed-citation xml:lang="ru">Morris STW, McMurray JJV, Spiers A, Jardine AG. Impaired endothelial function in isolated human uremical resistance arteries. Kidney Int2001; 60(3): 1077-1081</mixed-citation><mixed-citation xml:lang="en">Morris STW, McMurray JJV, Spiers A, Jardine AG. Impaired endothelial function in isolated human uremical resistance arteries. Kidney Int2001; 60(3): 1077-1081</mixed-citation></citation-alternatives></ref><ref id="cit73"><label>73</label><citation-alternatives><mixed-citation xml:lang="ru">Bennet-Richards KJ, Kattenhorn M, Donald AE et al. Oral L-arginine does not improve endothelial dysfunction in children with chronic renal failure. Kidney Int 2002; 62(4): 1372-1377</mixed-citation><mixed-citation xml:lang="en">Bennet-Richards KJ, Kattenhorn M, Donald AE et al. Oral L-arginine does not improve endothelial dysfunction in children with chronic renal failure. Kidney Int 2002; 62(4): 1372-1377</mixed-citation></citation-alternatives></ref><ref id="cit74"><label>74</label><citation-alternatives><mixed-citation xml:lang="ru">Yao Q, Lindholm B, Stenvinkel P. Inflammation as a cause of malnutrition, atherosclerotic cardiovascular disease, and poor outcome in hemodialysis patients. Hemodialysis Int 2004; 8(2): 118-123</mixed-citation><mixed-citation xml:lang="en">Yao Q, Lindholm B, Stenvinkel P. Inflammation as a cause of malnutrition, atherosclerotic cardiovascular disease, and poor outcome in hemodialysis patients. Hemodialysis Int 2004; 8(2): 118-123</mixed-citation></citation-alternatives></ref><ref id="cit75"><label>75</label><citation-alternatives><mixed-citation xml:lang="ru">Tyralla K, Amann K. Morphology of the heart and arteries in renal failure. Kidney Int 2003; 63 [suppl] 84: 80-85</mixed-citation><mixed-citation xml:lang="en">Tyralla K, Amann K. Morphology of the heart and arteries in renal failure. Kidney Int 2003; 63 [suppl] 84: 80-85</mixed-citation></citation-alternatives></ref><ref id="cit76"><label>76</label><citation-alternatives><mixed-citation xml:lang="ru">Kazuhiro S. Expression and regulation of endothelial nitric oxide synthase. TCM 1997; 7(1): 28-37</mixed-citation><mixed-citation xml:lang="en">Kazuhiro S. Expression and regulation of endothelial nitric oxide synthase. TCM 1997; 7(1): 28-37</mixed-citation></citation-alternatives></ref><ref id="cit77"><label>77</label><citation-alternatives><mixed-citation xml:lang="ru">Robert MF, Rabelink TJ. Atherosclerosis and two faces of endothelial nitric oxide synthase. Circulation 1998; 97: 108-112</mixed-citation><mixed-citation xml:lang="en">Robert MF, Rabelink TJ. Atherosclerosis and two faces of endothelial nitric oxide synthase. Circulation 1998; 97: 108-112</mixed-citation></citation-alternatives></ref><ref id="cit78"><label>78</label><citation-alternatives><mixed-citation xml:lang="ru">Шебеко ВИ, Родионов ЮЯ. Дисфункция эндотелия при гиперхолестеринемии и атеросклерозе. Мед Новости 1997; (11): 12-17</mixed-citation><mixed-citation xml:lang="en">Шебеко ВИ, Родионов ЮЯ. Дисфункция эндотелия при гиперхолестеринемии и атеросклерозе. Мед Новости 1997; (11): 12-17</mixed-citation></citation-alternatives></ref><ref id="cit79"><label>79</label><citation-alternatives><mixed-citation xml:lang="ru">Holvoet P. Endothelial dysfunction, oxidation of low-density lipoprotein and cardiovascular disease. Ther Apheresis and Dialysis 1999; 3(4): 287-292</mixed-citation><mixed-citation xml:lang="en">Holvoet P. Endothelial dysfunction, oxidation of low-density lipoprotein and cardiovascular disease. Ther Apheresis and Dialysis 1999; 3(4): 287-292</mixed-citation></citation-alternatives></ref><ref id="cit80"><label>80</label><citation-alternatives><mixed-citation xml:lang="ru">Galle J, Schneider R, Heinloth A et al. Lp(a) and LDL induce apoptosis in human endothelial cells and in rabbit aorta: role of oxidative stress. Kidney Int 1999; 55(4): 1450-1456</mixed-citation><mixed-citation xml:lang="en">Galle J, Schneider R, Heinloth A et al. Lp(a) and LDL induce apoptosis in human endothelial cells and in rabbit aorta: role of oxidative stress. Kidney Int 1999; 55(4): 1450-1456</mixed-citation></citation-alternatives></ref><ref id="cit81"><label>81</label><citation-alternatives><mixed-citation xml:lang="ru">Heermeir K, Schneider R, Heinloth A et al. Oxidative stress mediates apoptosis induced by oxidized low-density lipoprotein and oxidized lipoprotein(a). Kidney Int 1999; 56(4): 1310-1315</mixed-citation><mixed-citation xml:lang="en">Heermeir K, Schneider R, Heinloth A et al. Oxidative stress mediates apoptosis induced by oxidized low-density lipoprotein and oxidized lipoprotein(a). Kidney Int 1999; 56(4): 1310-1315</mixed-citation></citation-alternatives></ref><ref id="cit82"><label>82</label><citation-alternatives><mixed-citation xml:lang="ru">Ludmer PL, Selwyn AP, Shook TL et al. Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteries. N Engl J Med 1986; 315: 1046-1051</mixed-citation><mixed-citation xml:lang="en">Ludmer PL, Selwyn AP, Shook TL et al. Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteries. N Engl J Med 1986; 315: 1046-1051</mixed-citation></citation-alternatives></ref><ref id="cit83"><label>83</label><citation-alternatives><mixed-citation xml:lang="ru">Britten MB, Zeiher AM, Schachinger V. Clinical importance of coronary endothelial vasodilator dysfunction and therapeutic options. J Intern Med 1999; 245(4): 315-321</mixed-citation><mixed-citation xml:lang="en">Britten MB, Zeiher AM, Schachinger V. Clinical importance of coronary endothelial vasodilator dysfunction and therapeutic options. J Intern Med 1999; 245(4): 315-321</mixed-citation></citation-alternatives></ref><ref id="cit84"><label>84</label><citation-alternatives><mixed-citation xml:lang="ru">Noon JP, Walker BR, Hand MF, Webb HD. Studies with iontophoretic administration of drugs to human dermal vessels in vivo: cholinergic vasodilatation is mediated by dilator prostanoids rather than nitric oxide. Br J Clin Pharmacol 1998; 45 (6): 545–551</mixed-citation><mixed-citation xml:lang="en">Noon JP, Walker BR, Hand MF, Webb HD. Studies with iontophoretic administration of drugs to human dermal vessels in vivo: cholinergic vasodilatation is mediated by dilator prostanoids rather than nitric oxide. Br J Clin Pharmacol 1998; 45 (6): 545–551</mixed-citation></citation-alternatives></ref><ref id="cit85"><label>85</label><citation-alternatives><mixed-citation xml:lang="ru">Creager MA, Cooke JP, Mendelsohn MP et al. Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans. J Clin Invest 1990; 86: 228-234</mixed-citation><mixed-citation xml:lang="en">Creager MA, Cooke JP, Mendelsohn MP et al. Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans. J Clin Invest 1990; 86: 228-234</mixed-citation></citation-alternatives></ref><ref id="cit86"><label>86</label><citation-alternatives><mixed-citation xml:lang="ru">Lu Q, Eriksson M, Jogestrand T et al. Micro- and macrocirculatory effects of apheresis in patients with familial hyperlipidemia. Ther Apheresis and Dialysis 2003; 7(1): 115-120</mixed-citation><mixed-citation xml:lang="en">Lu Q, Eriksson M, Jogestrand T et al. Micro- and macrocirculatory effects of apheresis in patients with familial hyperlipidemia. Ther Apheresis and Dialysis 2003; 7(1): 115-120</mixed-citation></citation-alternatives></ref><ref id="cit87"><label>87</label><citation-alternatives><mixed-citation xml:lang="ru">Freiman PC, Mitchell GG, Heistad DD et al. Atherosclerosis impairs endothelium-dependent vascular relaxation to acetylcholine and thrombin in primates. Circ Res 1986; 58: 783-789</mixed-citation><mixed-citation xml:lang="en">Freiman PC, Mitchell GG, Heistad DD et al. Atherosclerosis impairs endothelium-dependent vascular relaxation to acetylcholine and thrombin in primates. Circ Res 1986; 58: 783-789</mixed-citation></citation-alternatives></ref><ref id="cit88"><label>88</label><citation-alternatives><mixed-citation xml:lang="ru">Harrison DG, Armstrong ML, Freiman PC et al. Restoration of endothelium-dependent relaxation by dietary treatment of atherosclerosis. J Clin Invest 1987; 80: 1808-1811</mixed-citation><mixed-citation xml:lang="en">Harrison DG, Armstrong ML, Freiman PC et al. Restoration of endothelium-dependent relaxation by dietary treatment of atherosclerosis. J Clin Invest 1987; 80: 1808-1811</mixed-citation></citation-alternatives></ref><ref id="cit89"><label>89</label><citation-alternatives><mixed-citation xml:lang="ru">Marchesi S, Lupattelli G, Siepi D et al. Oral L-arginine administration attenuates postprandial endothelial dysfunction in young healthy males. J Clin Pharm Ther 2001; 25(5): 343-349</mixed-citation><mixed-citation xml:lang="en">Marchesi S, Lupattelli G, Siepi D et al. Oral L-arginine administration attenuates postprandial endothelial dysfunction in young healthy males. J Clin Pharm Ther 2001; 25(5): 343-349</mixed-citation></citation-alternatives></ref><ref id="cit90"><label>90</label><citation-alternatives><mixed-citation xml:lang="ru">Algotsson A. Serum lipids and lipoproteins are correlated to skin vessel reactivity in healthy women. J Interrn Med 1996; 239(2): 147-153</mixed-citation><mixed-citation xml:lang="en">Algotsson A. Serum lipids and lipoproteins are correlated to skin vessel reactivity in healthy women. J Interrn Med 1996; 239(2): 147-153</mixed-citation></citation-alternatives></ref><ref id="cit91"><label>91</label><citation-alternatives><mixed-citation xml:lang="ru">Harrison DG, Armstrong ML, Freiman PC et al. Restoration of endothelium-dependent relaxation by dietary treatment of atherosclerosis. J Clin Invest 1987; 80: 1808-1811</mixed-citation><mixed-citation xml:lang="en">Harrison DG, Armstrong ML, Freiman PC et al. Restoration of endothelium-dependent relaxation by dietary treatment of atherosclerosis. J Clin Invest 1987; 80: 1808-1811</mixed-citation></citation-alternatives></ref><ref id="cit92"><label>92</label><citation-alternatives><mixed-citation xml:lang="ru">Benzuly KH, Padgett RC, Kaul S et al. Functional improvement precedes structural regression of atherosclerosis. Circulation 1994; 89: 1810-1818</mixed-citation><mixed-citation xml:lang="en">Benzuly KH, Padgett RC, Kaul S et al. Functional improvement precedes structural regression of atherosclerosis. Circulation 1994; 89: 1810-1818</mixed-citation></citation-alternatives></ref><ref id="cit93"><label>93</label><citation-alternatives><mixed-citation xml:lang="ru">Srisawat S, Phivthong-Ingam L, Unchern S et al. Improvement of vascular function by chronic administration of a cyclo-oxygenase inhibitor in cholesterol-fed rabbits. Clin Exp Pharm Physiol 2003; 30 (5-6): 405-409</mixed-citation><mixed-citation xml:lang="en">Srisawat S, Phivthong-Ingam L, Unchern S et al. Improvement of vascular function by chronic administration of a cyclo-oxygenase inhibitor in cholesterol-fed rabbits. Clin Exp Pharm Physiol 2003; 30 (5-6): 405-409</mixed-citation></citation-alternatives></ref><ref id="cit94"><label>94</label><citation-alternatives><mixed-citation xml:lang="ru">Beckman JS, Koppenol WH. Nitric oxide, superoxide and peroxynitrite: the good, the bad and the ugly. Am J Physiol 1996; 271: 1424-1437</mixed-citation><mixed-citation xml:lang="en">Beckman JS, Koppenol WH. Nitric oxide, superoxide and peroxynitrite: the good, the bad and the ugly. Am J Physiol 1996; 271: 1424-1437</mixed-citation></citation-alternatives></ref><ref id="cit95"><label>95</label><citation-alternatives><mixed-citation xml:lang="ru">Sand C, Peters SLM, Pfaffendorf M et al. Effects of hypochlorite and hydrogen peroxide on cardiac autonomic receptors and vascular endothelial function. Clin Exp Pharm Physiol 2003; 30 (4): 249-255</mixed-citation><mixed-citation xml:lang="en">Sand C, Peters SLM, Pfaffendorf M et al. Effects of hypochlorite and hydrogen peroxide on cardiac autonomic receptors and vascular endothelial function. Clin Exp Pharm Physiol 2003; 30 (4): 249-255</mixed-citation></citation-alternatives></ref><ref id="cit96"><label>96</label><citation-alternatives><mixed-citation xml:lang="ru">Martinet W, De Meyer GRY, Herman AG, Kockx M. Reactive oxygen species induce RNA damage in human atherosclerosis. Eur J Clin Invest 2004; 34(5): 323-329</mixed-citation><mixed-citation xml:lang="en">Martinet W, De Meyer GRY, Herman AG, Kockx M. Reactive oxygen species induce RNA damage in human atherosclerosis. Eur J Clin Invest 2004; 34(5): 323-329</mixed-citation></citation-alternatives></ref><ref id="cit97"><label>97</label><citation-alternatives><mixed-citation xml:lang="ru">Баранова ЕИ, Большакова ОО. Клиническое значение гипергомоцистеинемии. Артериальная гипертензия 2004; 10(1): 12-15</mixed-citation><mixed-citation xml:lang="en">Баранова ЕИ, Большакова ОО. Клиническое значение гипергомоцистеинемии. Артериальная гипертензия 2004; 10(1): 12-15</mixed-citation></citation-alternatives></ref><ref id="cit98"><label>98</label><citation-alternatives><mixed-citation xml:lang="ru">Malinow MR. Hyperhomocysteinemia: a common and easily reversible risk factor for occlusive atherosclerosis. Circulation 1990; 81: 2004-2006</mixed-citation><mixed-citation xml:lang="en">Malinow MR. Hyperhomocysteinemia: a common and easily reversible risk factor for occlusive atherosclerosis. Circulation 1990; 81: 2004-2006</mixed-citation></citation-alternatives></ref><ref id="cit99"><label>99</label><citation-alternatives><mixed-citation xml:lang="ru">Stampfer MJ, Malinow MR, Willett WC et al. A prospective study of plasma homocysteine and risk of myocardial infarction in US physicians. JAMA 1992; 268: 877-881</mixed-citation><mixed-citation xml:lang="en">Stampfer MJ, Malinow MR, Willett WC et al. A prospective study of plasma homocysteine and risk of myocardial infarction in US physicians. JAMA 1992; 268: 877-881</mixed-citation></citation-alternatives></ref><ref id="cit100"><label>100</label><citation-alternatives><mixed-citation xml:lang="ru">Selhub J, Jacques PF, Boston AG et al. Association between plasma homocysteine concentrations and extracranial catotid-artery stenosis. N Engl J Med 1995; 332: 286-291</mixed-citation><mixed-citation xml:lang="en">Selhub J, Jacques PF, Boston AG et al. Association between plasma homocysteine concentrations and extracranial catotid-artery stenosis. N Engl J Med 1995; 332: 286-291</mixed-citation></citation-alternatives></ref><ref id="cit101"><label>101</label><citation-alternatives><mixed-citation xml:lang="ru">Stampfer M, Malinow M. Can lowering homocysteine levels reduce cardiovascular risk? N Engl J Med 1995; 332: 328-329</mixed-citation><mixed-citation xml:lang="en">Stampfer M, Malinow M. Can lowering homocysteine levels reduce cardiovascular risk? N Engl J Med 1995; 332: 328-329</mixed-citation></citation-alternatives></ref><ref id="cit102"><label>102</label><citation-alternatives><mixed-citation xml:lang="ru">Graham M, Daly L, Refsum H et al. Plasma homocysteine as a risk factor for vascular disease: the European concerted action project. JAMA 1997; 277(22): 1775-1781</mixed-citation><mixed-citation xml:lang="en">Graham M, Daly L, Refsum H et al. Plasma homocysteine as a risk factor for vascular disease: the European concerted action project. JAMA 1997; 277(22): 1775-1781</mixed-citation></citation-alternatives></ref><ref id="cit103"><label>103</label><citation-alternatives><mixed-citation xml:lang="ru">Tawacol A, Omland T, Gerhard M et al. Hyperhomocyst(e)inemia is associated with impaired endothelium dependent vasodilation in humans. Circulation 1997; 95: 1119-1121</mixed-citation><mixed-citation xml:lang="en">Tawacol A, Omland T, Gerhard M et al. Hyperhomocyst(e)inemia is associated with impaired endothelium dependent vasodilation in humans. Circulation 1997; 95: 1119-1121</mixed-citation></citation-alternatives></ref><ref id="cit104"><label>104</label><citation-alternatives><mixed-citation xml:lang="ru">Welch G, Loscalzo J. Homocysteine and atherosclerosis. New Engl J Med 1998; 338(15): 1042-1050</mixed-citation><mixed-citation xml:lang="en">Welch G, Loscalzo J. Homocysteine and atherosclerosis. New Engl J Med 1998; 338(15): 1042-1050</mixed-citation></citation-alternatives></ref><ref id="cit105"><label>105</label><citation-alternatives><mixed-citation xml:lang="ru">Wang XL, Duarte N, Cai H et al. Relationship between total plasma homocysteine, polymorphisms of homocysteine metabolism related enzymes, risk factors and coronary artery disease in the Australian hospital-based population. Atherosclerosis 1999; 146: 133-140</mixed-citation><mixed-citation xml:lang="en">Wang XL, Duarte N, Cai H et al. Relationship between total plasma homocysteine, polymorphisms of homocysteine metabolism related enzymes, risk factors and coronary artery disease in the Australian hospital-based population. Atherosclerosis 1999; 146: 133-140</mixed-citation></citation-alternatives></ref><ref id="cit106"><label>106</label><citation-alternatives><mixed-citation xml:lang="ru">Harker LA, Ross R, Slichter SJ, Scott CR. Homocysteine-induced arteriosclerosis: the role of endothelial injury and platelet response in its genesis. J Clin Invest 1976; 58: 731-741</mixed-citation><mixed-citation xml:lang="en">Harker LA, Ross R, Slichter SJ, Scott CR. Homocysteine-induced arteriosclerosis: the role of endothelial injury and platelet response in its genesis. J Clin Invest 1976; 58: 731-741</mixed-citation></citation-alternatives></ref><ref id="cit107"><label>107</label><citation-alternatives><mixed-citation xml:lang="ru">Stamler JS, Osborne JA, Jaraki O et al. Adverse vascular effects of homocysteine are modulated by endothelial derived relaxing factor and related oxide of nitrogen. J Clin Invest 1993; 91: 308-318</mixed-citation><mixed-citation xml:lang="en">Stamler JS, Osborne JA, Jaraki O et al. Adverse vascular effects of homocysteine are modulated by endothelial derived relaxing factor and related oxide of nitrogen. J Clin Invest 1993; 91: 308-318</mixed-citation></citation-alternatives></ref><ref id="cit108"><label>108</label><citation-alternatives><mixed-citation xml:lang="ru">Van den Berg M, Boers GH, Franken DG et al. Hyperhomocysteinaemia and endothelial dysfunction in young patients with peripheral arterial occlusive disease. Eur J Clin Invest 1995; 25: 176-181</mixed-citation><mixed-citation xml:lang="en">Van den Berg M, Boers GH, Franken DG et al. Hyperhomocysteinaemia and endothelial dysfunction in young patients with peripheral arterial occlusive disease. Eur J Clin Invest 1995; 25: 176-181</mixed-citation></citation-alternatives></ref><ref id="cit109"><label>109</label><citation-alternatives><mixed-citation xml:lang="ru">Lentz SR, Sobey CG, Piegors DJ et al. Vascular dysfunction in monkeys with diet induced hyperhomocysteinemia. J Clin Invest 1996; 98: 24-29</mixed-citation><mixed-citation xml:lang="en">Lentz SR, Sobey CG, Piegors DJ et al. Vascular dysfunction in monkeys with diet induced hyperhomocysteinemia. J Clin Invest 1996; 98: 24-29</mixed-citation></citation-alternatives></ref><ref id="cit110"><label>110</label><citation-alternatives><mixed-citation xml:lang="ru">Woo KS, Chook P, Lolin YI et al. Hyperhomocysteinemia is a risk factor for arterial endothelial dysfunction in humans. Circulation 1997; 96: 2542-2544</mixed-citation><mixed-citation xml:lang="en">Woo KS, Chook P, Lolin YI et al. Hyperhomocysteinemia is a risk factor for arterial endothelial dysfunction in humans. Circulation 1997; 96: 2542-2544</mixed-citation></citation-alternatives></ref><ref id="cit111"><label>111</label><citation-alternatives><mixed-citation xml:lang="ru">Lambert J, van den Berg M, Steyn M et al. Familial hyperhomocysteinaemia and endothelium-dependent vasodilation and arterial distensibility of large arteries. Cardiovasc Res 1999; 42: 743-751</mixed-citation><mixed-citation xml:lang="en">Lambert J, van den Berg M, Steyn M et al. Familial hyperhomocysteinaemia and endothelium-dependent vasodilation and arterial distensibility of large arteries. Cardiovasc Res 1999; 42: 743-751</mixed-citation></citation-alternatives></ref><ref id="cit112"><label>112</label><citation-alternatives><mixed-citation xml:lang="ru">Шевченко ОП, Олефриенко ГА. Гипергомоцистеинемия и ее клиническое значение. Лаборатория 2002; (1): 3-7</mixed-citation><mixed-citation xml:lang="en">Шевченко ОП, Олефриенко ГА. Гипергомоцистеинемия и ее клиническое значение. Лаборатория 2002; (1): 3-7</mixed-citation></citation-alternatives></ref><ref id="cit113"><label>113</label><citation-alternatives><mixed-citation xml:lang="ru">Malinow MR. Homocyst(e)ine and arterial occlusive diseases. J Intern Med 1994; 236: 603-617</mixed-citation><mixed-citation xml:lang="en">Malinow MR. Homocyst(e)ine and arterial occlusive diseases. J Intern Med 1994; 236: 603-617</mixed-citation></citation-alternatives></ref><ref id="cit114"><label>114</label><citation-alternatives><mixed-citation xml:lang="ru">Berwanger CL, Jeremy JY, Stansby GD. Homocysteine and vascular disease. Br J Surg 1995; 82: 726-731</mixed-citation><mixed-citation xml:lang="en">Berwanger CL, Jeremy JY, Stansby GD. Homocysteine and vascular disease. Br J Surg 1995; 82: 726-731</mixed-citation></citation-alternatives></ref><ref id="cit115"><label>115</label><citation-alternatives><mixed-citation xml:lang="ru">Celermajer DS, Sorenson KE, Ryalls M et al. Impaired endothelial function occurs in the systemic arteries of children with homozygous homocysteinuria but not in their heterozygous parents. J Am Coll Cardiol 1993; 22: 854-858</mixed-citation><mixed-citation xml:lang="en">Celermajer DS, Sorenson KE, Ryalls M et al. Impaired endothelial function occurs in the systemic arteries of children with homozygous homocysteinuria but not in their heterozygous parents. J Am Coll Cardiol 1993; 22: 854-858</mixed-citation></citation-alternatives></ref><ref id="cit116"><label>116</label><citation-alternatives><mixed-citation xml:lang="ru">Upchurch GR, Welch G, Fabian A et al. Stimulation of endothelial nitric oxide production by homocysteine. Atherosclerosis 1997; 132: 177-185</mixed-citation><mixed-citation xml:lang="en">Upchurch GR, Welch G, Fabian A et al. Stimulation of endothelial nitric oxide production by homocysteine. Atherosclerosis 1997; 132: 177-185</mixed-citation></citation-alternatives></ref><ref id="cit117"><label>117</label><citation-alternatives><mixed-citation xml:lang="ru">Demuth K, Atger V, Borderie D et al. Homocysteine decreases endothelin-1 production by cultured human endothelial cells. Eur J Biochem 1999; 263(2): 367-372</mixed-citation><mixed-citation xml:lang="en">Demuth K, Atger V, Borderie D et al. Homocysteine decreases endothelin-1 production by cultured human endothelial cells. Eur J Biochem 1999; 263(2): 367-372</mixed-citation></citation-alternatives></ref><ref id="cit118"><label>118</label><citation-alternatives><mixed-citation xml:lang="ru">Emsley AM, Jeremy JY, Gomes GN et al. Investigation of the inhibitory effects of homocysteine and copper on nitric oxide-mediated relaxation of rat isolated aorta. Br J Pharmacol 1999; 126: 1034-1040</mixed-citation><mixed-citation xml:lang="en">Emsley AM, Jeremy JY, Gomes GN et al. Investigation of the inhibitory effects of homocysteine and copper on nitric oxide-mediated relaxation of rat isolated aorta. Br J Pharmacol 1999; 126: 1034-1040</mixed-citation></citation-alternatives></ref><ref id="cit119"><label>119</label><citation-alternatives><mixed-citation xml:lang="ru">Zhang X, Li H, Jin H et al. Effects of homocysteine on endothelial nitric oxide production. Am J Physiol Renal Physiol 2000; 279: 671-678</mixed-citation><mixed-citation xml:lang="en">Zhang X, Li H, Jin H et al. Effects of homocysteine on endothelial nitric oxide production. Am J Physiol Renal Physiol 2000; 279: 671-678</mixed-citation></citation-alternatives></ref><ref id="cit120"><label>120</label><citation-alternatives><mixed-citation xml:lang="ru">Weiss N, Heydrick SJ, Postea O et al. Influence of hyperhomocysteinemia on the cellular redox state – impact on homocysteine-induced endothelial dysfunction. Clin Chem Lab Med 2003; 41: 1455-1461</mixed-citation><mixed-citation xml:lang="en">Weiss N, Heydrick SJ, Postea O et al. Influence of hyperhomocysteinemia on the cellular redox state – impact on homocysteine-induced endothelial dysfunction. Clin Chem Lab Med 2003; 41: 1455-1461</mixed-citation></citation-alternatives></ref><ref id="cit121"><label>121</label><citation-alternatives><mixed-citation xml:lang="ru">Loscalzo J. The oxidant stress of hyperhomocysteinemia. J Clin Invest 1996; 98(1): 5-7</mixed-citation><mixed-citation xml:lang="en">Loscalzo J. The oxidant stress of hyperhomocysteinemia. J Clin Invest 1996; 98(1): 5-7</mixed-citation></citation-alternatives></ref><ref id="cit122"><label>122</label><citation-alternatives><mixed-citation xml:lang="ru">Jia L, Furchgott RF. Inhibition by sulph-hydryl compounds of vascular relaxation induced by nitric oxide and endothelium-derived relaxing factor. J Pharmacol Exp Ther 1993; 267: 371-378</mixed-citation><mixed-citation xml:lang="en">Jia L, Furchgott RF. Inhibition by sulph-hydryl compounds of vascular relaxation induced by nitric oxide and endothelium-derived relaxing factor. J Pharmacol Exp Ther 1993; 267: 371-378</mixed-citation></citation-alternatives></ref><ref id="cit123"><label>123</label><citation-alternatives><mixed-citation xml:lang="ru">Emsley A, Plane F, Angelini GD, Jeremy JY. Copper interacts with homocysteine to inhibit nitric oxide formation in the rat isolated aorta. Br J Pharmacol 1997; 122: 47-53</mixed-citation><mixed-citation xml:lang="en">Emsley A, Plane F, Angelini GD, Jeremy JY. Copper interacts with homocysteine to inhibit nitric oxide formation in the rat isolated aorta. Br J Pharmacol 1997; 122: 47-53</mixed-citation></citation-alternatives></ref><ref id="cit124"><label>124</label><citation-alternatives><mixed-citation xml:lang="ru">Glyglewski RJ, Palmer RMJ, Moncada S. Superoxide anion plays a role in the breakdown of endothelium-derived relaxing factor. Nature 1986; 320: 454-456</mixed-citation><mixed-citation xml:lang="en">Glyglewski RJ, Palmer RMJ, Moncada S. Superoxide anion plays a role in the breakdown of endothelium-derived relaxing factor. Nature 1986; 320: 454-456</mixed-citation></citation-alternatives></ref><ref id="cit125"><label>125</label><citation-alternatives><mixed-citation xml:lang="ru">Rubanyi GM, Vanhoutte PM. Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factors. Am J Physiol 1986; 250: H822-H827</mixed-citation><mixed-citation xml:lang="en">Rubanyi GM, Vanhoutte PM. Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factors. Am J Physiol 1986; 250: H822-H827</mixed-citation></citation-alternatives></ref><ref id="cit126"><label>126</label><citation-alternatives><mixed-citation xml:lang="ru">McAninly J, Williams DLH, Askew SC et al. Metal-ion catalysis in nitrosothiol (RSNO) decomposition. J Chem Soc Commun 1993; 23: 1758-1759</mixed-citation><mixed-citation xml:lang="en">McAninly J, Williams DLH, Askew SC et al. Metal-ion catalysis in nitrosothiol (RSNO) decomposition. J Chem Soc Commun 1993; 23: 1758-1759</mixed-citation></citation-alternatives></ref><ref id="cit127"><label>127</label><citation-alternatives><mixed-citation xml:lang="ru">Starkebaum G, Harlan JM. Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine. J Clin Invest 1986; 77: 1370-1376</mixed-citation><mixed-citation xml:lang="en">Starkebaum G, Harlan JM. Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine. J Clin Invest 1986; 77: 1370-1376</mixed-citation></citation-alternatives></ref><ref id="cit128"><label>128</label><citation-alternatives><mixed-citation xml:lang="ru">Heinecke JW, Rosen H, Suzuki LA, Chait A. The role of sulfur-containing amino acids in superoxide production and modification of low-density lipoprotein by arterial smooth muscle cells. J Biol Chem 1987; 262: 10098-10103</mixed-citation><mixed-citation xml:lang="en">Heinecke JW, Rosen H, Suzuki LA, Chait A. The role of sulfur-containing amino acids in superoxide production and modification of low-density lipoprotein by arterial smooth muscle cells. J Biol Chem 1987; 262: 10098-10103</mixed-citation></citation-alternatives></ref><ref id="cit129"><label>129</label><citation-alternatives><mixed-citation xml:lang="ru">Upchurch GR, Welch GN, Loscalzo J. Homocysteine, EDRF and endothelial function. J Nutr 1996; 126: 1290S-1294S</mixed-citation><mixed-citation xml:lang="en">Upchurch GR, Welch GN, Loscalzo J. Homocysteine, EDRF and endothelial function. J Nutr 1996; 126: 1290S-1294S</mixed-citation></citation-alternatives></ref><ref id="cit130"><label>130</label><citation-alternatives><mixed-citation xml:lang="ru">Welch G, Upchurch G, Loscalzo J. Hyperhomocysteinemia and atherothrombosis. Ann NY Acad Sci 1997; 811: 48-58</mixed-citation><mixed-citation xml:lang="en">Welch G, Upchurch G, Loscalzo J. Hyperhomocysteinemia and atherothrombosis. Ann NY Acad Sci 1997; 811: 48-58</mixed-citation></citation-alternatives></ref><ref id="cit131"><label>131</label><citation-alternatives><mixed-citation xml:lang="ru">Coppola A, Davi G, De Stefano V et al. Homocysteine, coagulation, platelet function, and thrombosis. Semin Thromb Hemost 2000; 26: 243-254</mixed-citation><mixed-citation xml:lang="en">Coppola A, Davi G, De Stefano V et al. Homocysteine, coagulation, platelet function, and thrombosis. Semin Thromb Hemost 2000; 26: 243-254</mixed-citation></citation-alternatives></ref><ref id="cit132"><label>132</label><citation-alternatives><mixed-citation xml:lang="ru">Fu W, Dudman N, Perry M, Wang H. Homocysteinemia attenuates hemodynamic responses to nitric oxide in vivo. Atherosclerosis 2002; 161(1): 169-176</mixed-citation><mixed-citation xml:lang="en">Fu W, Dudman N, Perry M, Wang H. Homocysteinemia attenuates hemodynamic responses to nitric oxide in vivo. Atherosclerosis 2002; 161(1): 169-176</mixed-citation></citation-alternatives></ref><ref id="cit133"><label>133</label><citation-alternatives><mixed-citation xml:lang="ru">Perna AF, Ingrosso D, Lombardi C et al. Possible mechanisms of homocysteine toxicity. Kidney Int 2003; 63 [suppl 84]: S137-S140</mixed-citation><mixed-citation xml:lang="en">Perna AF, Ingrosso D, Lombardi C et al. Possible mechanisms of homocysteine toxicity. Kidney Int 2003; 63 [suppl 84]: S137-S140</mixed-citation></citation-alternatives></ref><ref id="cit134"><label>134</label><citation-alternatives><mixed-citation xml:lang="ru">Hucks D, Thuraisingam RC, Raftery MJ, Yaqoob MM. Homocysteine induced impairment of nitric oxide-dependent vasorelaxation is reversible by the superoxide dismutase mimetic TEMPOL. Nephrol Dial Transplant 2004; 19(8): 1999-2005</mixed-citation><mixed-citation xml:lang="en">Hucks D, Thuraisingam RC, Raftery MJ, Yaqoob MM. Homocysteine induced impairment of nitric oxide-dependent vasorelaxation is reversible by the superoxide dismutase mimetic TEMPOL. Nephrol Dial Transplant 2004; 19(8): 1999-2005</mixed-citation></citation-alternatives></ref><ref id="cit135"><label>135</label><citation-alternatives><mixed-citation xml:lang="ru">Boaz M, Smetana S, Weinstein T et al. Secondary prevention with antioxidants of cardiovascular in end stage renal disease (SPACE): randomized placebo controlled trial. Lancet 2000; 356: 1213-1218</mixed-citation><mixed-citation xml:lang="en">Boaz M, Smetana S, Weinstein T et al. Secondary prevention with antioxidants of cardiovascular in end stage renal disease (SPACE): randomized placebo controlled trial. Lancet 2000; 356: 1213-1218</mixed-citation></citation-alternatives></ref><ref id="cit136"><label>136</label><citation-alternatives><mixed-citation xml:lang="ru">Tepel M, van der Giet M, Statz M et al. The antioxidant acetylcysteine reduces cardiovascular events in patients with end stage renal failure. Circulation 2003; 107: 992-994</mixed-citation><mixed-citation xml:lang="en">Tepel M, van der Giet M, Statz M et al. The antioxidant acetylcysteine reduces cardiovascular events in patients with end stage renal failure. Circulation 2003; 107: 992-994</mixed-citation></citation-alternatives></ref><ref id="cit137"><label>137</label><citation-alternatives><mixed-citation xml:lang="ru">Drunat S, Moati N, Paul JL. Homocysteine-induced decrease in endothelin-1 production is initiated at extracellular level and involves oxidative products. Eur J Biochem 2001; 268 (20): 5287-5291</mixed-citation><mixed-citation xml:lang="en">Drunat S, Moati N, Paul JL. Homocysteine-induced decrease in endothelin-1 production is initiated at extracellular level and involves oxidative products. Eur J Biochem 2001; 268 (20): 5287-5291</mixed-citation></citation-alternatives></ref><ref id="cit138"><label>138</label><citation-alternatives><mixed-citation xml:lang="ru">Pathasarathy S. Oxidation of low-density lipoprotein by thiol compounds leads to its recognition by acetyl LDL receptor. Biochem Biophys Acta 1987; 917: 337-340</mixed-citation><mixed-citation xml:lang="en">Pathasarathy S. Oxidation of low-density lipoprotein by thiol compounds leads to its recognition by acetyl LDL receptor. Biochem Biophys Acta 1987; 917: 337-340</mixed-citation></citation-alternatives></ref><ref id="cit139"><label>139</label><citation-alternatives><mixed-citation xml:lang="ru">Chin JH, Azhar S, Hoffman BB. Inactivation of endothelium-derived relaxing factor by oxidized lipoproteins. J Clin Invest 1992; 89: 10-18</mixed-citation><mixed-citation xml:lang="en">Chin JH, Azhar S, Hoffman BB. Inactivation of endothelium-derived relaxing factor by oxidized lipoproteins. J Clin Invest 1992; 89: 10-18</mixed-citation></citation-alternatives></ref><ref id="cit140"><label>140</label><citation-alternatives><mixed-citation xml:lang="ru">Blom HJ. Lipid peroxidation and susceptibility of low-density lipoprotein to in vitro oxidation in hyperhomocysteinemia. Eur J Clin Invest 1995; 25: 149-154</mixed-citation><mixed-citation xml:lang="en">Blom HJ. Lipid peroxidation and susceptibility of low-density lipoprotein to in vitro oxidation in hyperhomocysteinemia. Eur J Clin Invest 1995; 25: 149-154</mixed-citation></citation-alternatives></ref><ref id="cit141"><label>141</label><citation-alternatives><mixed-citation xml:lang="ru">Liao JK, Shin WS, Lee WY, Clark SL. Oxidized low-density lipoprotein decreases the expression of endothelial nitric oxide synthase. J Biol Chem 1995; 27: 319-324</mixed-citation><mixed-citation xml:lang="en">Liao JK, Shin WS, Lee WY, Clark SL. Oxidized low-density lipoprotein decreases the expression of endothelial nitric oxide synthase. J Biol Chem 1995; 27: 319-324</mixed-citation></citation-alternatives></ref><ref id="cit142"><label>142</label><citation-alternatives><mixed-citation xml:lang="ru">Tawacol A, Forgione M, Stueblinger M et al. Homocysteine impairs coronary microvascular dilator function in humans. JACC 2002; 40(6): 1051-1058</mixed-citation><mixed-citation xml:lang="en">Tawacol A, Forgione M, Stueblinger M et al. Homocysteine impairs coronary microvascular dilator function in humans. JACC 2002; 40(6): 1051-1058</mixed-citation></citation-alternatives></ref><ref id="cit143"><label>143</label><citation-alternatives><mixed-citation xml:lang="ru">Schnyder G, Roffi M, Pin R et al. Decreased rate of coronary restenosis after lowering of plasma homocysteine levels. N Engl J Med 2001; 345(22): 1593-1600</mixed-citation><mixed-citation xml:lang="en">Schnyder G, Roffi M, Pin R et al. Decreased rate of coronary restenosis after lowering of plasma homocysteine levels. N Engl J Med 2001; 345(22): 1593-1600</mixed-citation></citation-alternatives></ref><ref id="cit144"><label>144</label><citation-alternatives><mixed-citation xml:lang="ru">Van Dijk RA, Rauwerda JA, Steyn M et al. Long-term homocysteine-lowering treatment with folic acid plus pyridoxine is associated with decreased blood pressure but not with improved brachial artery endothelium-dependent vasodilation or carotid artery stiffness: a 2-year, randomized, placebo-controlled trial. Arterioscler Thromb Vasc Biol2001; 21: 2072-2079</mixed-citation><mixed-citation xml:lang="en">Van Dijk RA, Rauwerda JA, Steyn M et al. Long-term homocysteine-lowering treatment with folic acid plus pyridoxine is associated with decreased blood pressure but not with improved brachial artery endothelium-dependent vasodilation or carotid artery stiffness: a 2-year, randomized, placebo-controlled trial. Arterioscler Thromb Vasc Biol2001; 21: 2072-2079</mixed-citation></citation-alternatives></ref><ref id="cit145"><label>145</label><citation-alternatives><mixed-citation xml:lang="ru">Toole JF, Malinow MR, Chambless LE et al. Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: the Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial. JAMA 2004; 291: 565-575</mixed-citation><mixed-citation xml:lang="en">Toole JF, Malinow MR, Chambless LE et al. Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: the Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial. JAMA 2004; 291: 565-575</mixed-citation></citation-alternatives></ref><ref id="cit146"><label>146</label><citation-alternatives><mixed-citation xml:lang="ru">Wrone EM, Hornberger JM, Zehnder J et al. Randomized trial of folic acid for prevention of cardiovascular events in end-stage renal disease. J Am Soc Nephrol 2004; 15: 420-426</mixed-citation><mixed-citation xml:lang="en">Wrone EM, Hornberger JM, Zehnder J et al. Randomized trial of folic acid for prevention of cardiovascular events in end-stage renal disease. J Am Soc Nephrol 2004; 15: 420-426</mixed-citation></citation-alternatives></ref><ref id="cit147"><label>147</label><citation-alternatives><mixed-citation xml:lang="ru">Van Guldener C, Janssen MJ, Lambert J et al. No change in impaired endothelial function after long-term folic acid therapy of hyperhomocysteinaemia in haemodialysis patients. Nephrol Dial Transplant 1998; 13: 106-112</mixed-citation><mixed-citation xml:lang="en">Van Guldener C, Janssen MJ, Lambert J et al. No change in impaired endothelial function after long-term folic acid therapy of hyperhomocysteinaemia in haemodialysis patients. Nephrol Dial Transplant 1998; 13: 106-112</mixed-citation></citation-alternatives></ref><ref id="cit148"><label>148</label><citation-alternatives><mixed-citation xml:lang="ru">Austen SK, Coombes JS, Fassett RG. Homocysteine-lowering therapy in renal disease. Clin Nephrol 2003; 60: 375-385</mixed-citation><mixed-citation xml:lang="en">Austen SK, Coombes JS, Fassett RG. Homocysteine-lowering therapy in renal disease. Clin Nephrol 2003; 60: 375-385</mixed-citation></citation-alternatives></ref><ref id="cit149"><label>149</label><citation-alternatives><mixed-citation xml:lang="ru">Vallance P, Leone A, Calver A et al. Endogenous dimethylarginine as an inhibitor of nitric oxide synthesis. J Cardiovasc Pharmacol 1992; 20 [suppl 12]: S60-S62</mixed-citation><mixed-citation xml:lang="en">Vallance P, Leone A, Calver A et al. Endogenous dimethylarginine as an inhibitor of nitric oxide synthesis. J Cardiovasc Pharmacol 1992; 20 [suppl 12]: S60-S62</mixed-citation></citation-alternatives></ref><ref id="cit150"><label>150</label><citation-alternatives><mixed-citation xml:lang="ru">Fickling SA, Leone AM, Nussey SS et al. Synthesis of NG, Ng dimethylarginine by human endothelial cells. Endothelium 1993; 1: 137–140</mixed-citation><mixed-citation xml:lang="en">Fickling SA, Leone AM, Nussey SS et al. Synthesis of NG, Ng dimethylarginine by human endothelial cells. Endothelium 1993; 1: 137–140</mixed-citation></citation-alternatives></ref><ref id="cit151"><label>151</label><citation-alternatives><mixed-citation xml:lang="ru">Boger RH, Bode-Boger SM, Tsao PS et al. The endogenous NO synthase inhibitor asymmetric dimethylarginine (ADMA) exerts pro-atherosclerotic effects in cultural human endothelial cells. Circulation 1997; 96; [suppl 1]: 1588</mixed-citation><mixed-citation xml:lang="en">Boger RH, Bode-Boger SM, Tsao PS et al. The endogenous NO synthase inhibitor asymmetric dimethylarginine (ADMA) exerts pro-atherosclerotic effects in cultural human endothelial cells. Circulation 1997; 96; [suppl 1]: 1588</mixed-citation></citation-alternatives></ref><ref id="cit152"><label>152</label><citation-alternatives><mixed-citation xml:lang="ru">Bode-Boger SM, Boger RH, Kieke S et al. Elevated L-arginine/dimethylarginine ratio contributes to enhanced systemic NO production by dietary L-arginine in hypercholesterolemic rabbits. Biochem Biophys Res Commun 1996; 219: 598-603</mixed-citation><mixed-citation xml:lang="en">Bode-Boger SM, Boger RH, Kieke S et al. Elevated L-arginine/dimethylarginine ratio contributes to enhanced systemic NO production by dietary L-arginine in hypercholesterolemic rabbits. Biochem Biophys Res Commun 1996; 219: 598-603</mixed-citation></citation-alternatives></ref><ref id="cit153"><label>153</label><citation-alternatives><mixed-citation xml:lang="ru">Boger RH, Bode-Boger SM, Phivthong-Ingam L et al. Dietary L-arginine slows the progression of atherosclerosis in cholesterol-fed rabbits: comparison with lovastatin. Circulation 1997; 96: 1282-1290</mixed-citation><mixed-citation xml:lang="en">Boger RH, Bode-Boger SM, Phivthong-Ingam L et al. Dietary L-arginine slows the progression of atherosclerosis in cholesterol-fed rabbits: comparison with lovastatin. Circulation 1997; 96: 1282-1290</mixed-citation></citation-alternatives></ref><ref id="cit154"><label>154</label><citation-alternatives><mixed-citation xml:lang="ru">Boger RH, Bode-Boger SM, Thiele W et al. Biochemical evidence for impaired nitric oxide synthesis in patients with peripheral arterial occlusive. Circulation 1997; 95: 2068-2074</mixed-citation><mixed-citation xml:lang="en">Boger RH, Bode-Boger SM, Thiele W et al. Biochemical evidence for impaired nitric oxide synthesis in patients with peripheral arterial occlusive. Circulation 1997; 95: 2068-2074</mixed-citation></citation-alternatives></ref><ref id="cit155"><label>155</label><citation-alternatives><mixed-citation xml:lang="ru">Boger RH, Bode-Boger SM, Szuba A et al. Asymmetric dimethylarginine: a novel risk factor for endothelial dysfunction: its role in hypercholesterolemia. Circulation 1998; 98: 1842-1847</mixed-citation><mixed-citation xml:lang="en">Boger RH, Bode-Boger SM, Szuba A et al. Asymmetric dimethylarginine: a novel risk factor for endothelial dysfunction: its role in hypercholesterolemia. Circulation 1998; 98: 1842-1847</mixed-citation></citation-alternatives></ref><ref id="cit156"><label>156</label><citation-alternatives><mixed-citation xml:lang="ru">Malinow MR. Homocyst(e)ine and arterial occlusive diseases. J Intern Med 1994; 236: 603-617</mixed-citation><mixed-citation xml:lang="en">Malinow MR. Homocyst(e)ine and arterial occlusive diseases. J Intern Med 1994; 236: 603-617</mixed-citation></citation-alternatives></ref><ref id="cit157"><label>157</label><citation-alternatives><mixed-citation xml:lang="ru">Boger RH, Bode-Boger SM, Sydow K et al. Plasma concentration of asymmetric dymethylarginine, an endogenous inhibitor of nitric oxide synthase, is elevated in monkeys with hyperhomocyst(e)inemia or hypercholesterolemia. Arterioscler Thromb Vasc Biol 2000: 20; 1557-1561</mixed-citation><mixed-citation xml:lang="en">Boger RH, Bode-Boger SM, Sydow K et al. Plasma concentration of asymmetric dymethylarginine, an endogenous inhibitor of nitric oxide synthase, is elevated in monkeys with hyperhomocyst(e)inemia or hypercholesterolemia. Arterioscler Thromb Vasc Biol 2000: 20; 1557-1561</mixed-citation></citation-alternatives></ref><ref id="cit158"><label>158</label><citation-alternatives><mixed-citation xml:lang="ru">Hornig B, Bode-Boger SM, Arakawa N et al. Lack of improvement of homocyst(e)ine-induced endothelial dysfunction during supplementation with B vitamins in patients with arterial occlusive disease. Circulation 1999; 100 [suppl 1]: 757</mixed-citation><mixed-citation xml:lang="en">Hornig B, Bode-Boger SM, Arakawa N et al. Lack of improvement of homocyst(e)ine-induced endothelial dysfunction during supplementation with B vitamins in patients with arterial occlusive disease. Circulation 1999; 100 [suppl 1]: 757</mixed-citation></citation-alternatives></ref><ref id="cit159"><label>159</label><citation-alternatives><mixed-citation xml:lang="ru">Zoccali C, Mallamaci LS, Maas R et al. Left ventricular hypertrophy, cardiac remodeling and asymmetric dimethylarginine (ADMA) in hemodialysis patients. Kidney Int 2002; 62(1): 339-345</mixed-citation><mixed-citation xml:lang="en">Zoccali C, Mallamaci LS, Maas R et al. Left ventricular hypertrophy, cardiac remodeling and asymmetric dimethylarginine (ADMA) in hemodialysis patients. Kidney Int 2002; 62(1): 339-345</mixed-citation></citation-alternatives></ref><ref id="cit160"><label>160</label><citation-alternatives><mixed-citation xml:lang="ru">Fliser D, Kielstein JT, Haller H, Bode-Boger SM. Asymmetric dimethylarginine: A cardiovascular risk factor in renal disease? Kidney Int 2003; 63 [suppl 84]: 37-43</mixed-citation><mixed-citation xml:lang="en">Fliser D, Kielstein JT, Haller H, Bode-Boger SM. Asymmetric dimethylarginine: A cardiovascular risk factor in renal disease? Kidney Int 2003; 63 [suppl 84]: 37-43</mixed-citation></citation-alternatives></ref><ref id="cit161"><label>161</label><citation-alternatives><mixed-citation xml:lang="ru">Zoccali C, Mallamaci F, Tripepi G. Traditional and emerging cardiovascular risk factors in end-stage renal disease. Kidney Int 2003; 63 [suppl 85]: 105-111</mixed-citation><mixed-citation xml:lang="en">Zoccali C, Mallamaci F, Tripepi G. Traditional and emerging cardiovascular risk factors in end-stage renal disease. Kidney Int 2003; 63 [suppl 85]: 105-111</mixed-citation></citation-alternatives></ref><ref id="cit162"><label>162</label><citation-alternatives><mixed-citation xml:lang="ru">Suliman ME, Stenvinkel P, Heimburger O et al. Plasma sulfur amino acids in relation to cardiovascular disease, nutritional status, and diabetes mellitus in patients with chronic renal failure at start of dialysis therapy. Am J Kidney Dis 2002; 40: 480-488</mixed-citation><mixed-citation xml:lang="en">Suliman ME, Stenvinkel P, Heimburger O et al. Plasma sulfur amino acids in relation to cardiovascular disease, nutritional status, and diabetes mellitus in patients with chronic renal failure at start of dialysis therapy. Am J Kidney Dis 2002; 40: 480-488</mixed-citation></citation-alternatives></ref><ref id="cit163"><label>163</label><citation-alternatives><mixed-citation xml:lang="ru">Faraci FM, Orgren K, Heistad DD. Impaired relaxation of the carotid artery during activation of ATP-sensitive potassium channels in atherosclerotic monkeys. Stroke 1994; 25: 178-182</mixed-citation><mixed-citation xml:lang="en">Faraci FM, Orgren K, Heistad DD. Impaired relaxation of the carotid artery during activation of ATP-sensitive potassium channels in atherosclerotic monkeys. Stroke 1994; 25: 178-182</mixed-citation></citation-alternatives></ref><ref id="cit164"><label>164</label><citation-alternatives><mixed-citation xml:lang="ru">Tsai JC, Perrella MA, Yoshizumi M et al. Promotion of vascular smooth muscle cell growth by homocysteine: a link to atherosclerosis. Proc Natl Acad Sci USA 1994; 91: 6369-6373</mixed-citation><mixed-citation xml:lang="en">Tsai JC, Perrella MA, Yoshizumi M et al. Promotion of vascular smooth muscle cell growth by homocysteine: a link to atherosclerosis. Proc Natl Acad Sci USA 1994; 91: 6369-6373</mixed-citation></citation-alternatives></ref><ref id="cit165"><label>165</label><citation-alternatives><mixed-citation xml:lang="ru">Tang L, Mamotte CD, van Bockxmeer FM, Taylor RR. The effect homocysteine on DNA synthesis in cultured human vascular smooth muscle. Atherosclerosis 1998; 136: 169-173</mixed-citation><mixed-citation xml:lang="en">Tang L, Mamotte CD, van Bockxmeer FM, Taylor RR. The effect homocysteine on DNA synthesis in cultured human vascular smooth muscle. Atherosclerosis 1998; 136: 169-173</mixed-citation></citation-alternatives></ref><ref id="cit166"><label>166</label><citation-alternatives><mixed-citation xml:lang="ru">Hansrani M, Gillespie J, Stransby G. Homocyseine in myointimal hyperplasia. Eur J Vasc Endovasc Surg 2002; 23: 3-10</mixed-citation><mixed-citation xml:lang="en">Hansrani M, Gillespie J, Stransby G. Homocyseine in myointimal hyperplasia. Eur J Vasc Endovasc Surg 2002; 23: 3-10</mixed-citation></citation-alternatives></ref><ref id="cit167"><label>167</label><citation-alternatives><mixed-citation xml:lang="ru">Majors A, Ehrhart LA, Pezacka EH. Homocysteine as a risk factor for vascular disease: enhanced collagen production and accumulation by smooth muscle cells. Arterioscler Thromb Vasc Biol 1997; 17: 2074-2081</mixed-citation><mixed-citation xml:lang="en">Majors A, Ehrhart LA, Pezacka EH. Homocysteine as a risk factor for vascular disease: enhanced collagen production and accumulation by smooth muscle cells. Arterioscler Thromb Vasc Biol 1997; 17: 2074-2081</mixed-citation></citation-alternatives></ref><ref id="cit168"><label>168</label><citation-alternatives><mixed-citation xml:lang="ru">Noris M, Remuzzi G. Physiology and pathophysiology of nitric oxide in chronic renal disease. Proc Assoc Am Phys 1999; 111(6): 602-608</mixed-citation><mixed-citation xml:lang="en">Noris M, Remuzzi G. Physiology and pathophysiology of nitric oxide in chronic renal disease. Proc Assoc Am Phys 1999; 111(6): 602-608</mixed-citation></citation-alternatives></ref><ref id="cit169"><label>169</label><citation-alternatives><mixed-citation xml:lang="ru">Benchetrit S, Green J, Katz D et al. Early endothelial dysfunction following renal mass reduction in rats. Eur J Clin Invest 2003; 33(1): 26-31</mixed-citation><mixed-citation xml:lang="en">Benchetrit S, Green J, Katz D et al. Early endothelial dysfunction following renal mass reduction in rats. Eur J Clin Invest 2003; 33(1): 26-31</mixed-citation></citation-alternatives></ref><ref id="cit170"><label>170</label><citation-alternatives><mixed-citation xml:lang="ru">Asahi K, Ichimori K, Nakazawa H et al. Nitric oxide inhibits the formation of advanced end products. Kidney Int 2000; 58(4): 1780-1785</mixed-citation><mixed-citation xml:lang="en">Asahi K, Ichimori K, Nakazawa H et al. Nitric oxide inhibits the formation of advanced end products. Kidney Int 2000; 58(4): 1780-1785</mixed-citation></citation-alternatives></ref><ref id="cit171"><label>171</label><citation-alternatives><mixed-citation xml:lang="ru">Stenvinkel P, Alvestrand A. Review Articles Inflammation in end-stage renal disease: sources, consequences and therapy. Semin Dialysis 2002; 15(5): 329-335</mixed-citation><mixed-citation xml:lang="en">Stenvinkel P, Alvestrand A. Review Articles Inflammation in end-stage renal disease: sources, consequences and therapy. Semin Dialysis 2002; 15(5): 329-335</mixed-citation></citation-alternatives></ref><ref id="cit172"><label>172</label><citation-alternatives><mixed-citation xml:lang="ru">Ребров АП, Зелепукина НЮ. Дисфункция эндотелия у больных хроническим гломерулонефритом в различных стадиях почечной недостаточности. Нефрология и диализ 2001; 3(4): 39-46</mixed-citation><mixed-citation xml:lang="en">Ребров АП, Зелепукина НЮ. Дисфункция эндотелия у больных хроническим гломерулонефритом в различных стадиях почечной недостаточности. Нефрология и диализ 2001; 3(4): 39-46</mixed-citation></citation-alternatives></ref><ref id="cit173"><label>173</label><citation-alternatives><mixed-citation xml:lang="ru">Watts GF, Herrmann S, Dogra GK et al. Vascular function of the peripheral circulation in patients with nephrosis. Kidney Int 2001; 60(1): 182-187</mixed-citation><mixed-citation xml:lang="en">Watts GF, Herrmann S, Dogra GK et al. Vascular function of the peripheral circulation in patients with nephrosis. Kidney Int 2001; 60(1): 182-187</mixed-citation></citation-alternatives></ref><ref id="cit174"><label>174</label><citation-alternatives><mixed-citation xml:lang="ru">Dogra GK, Watts GF, Herrmann S et al. Statin therapy improves brachial artery endothelial function in nephrotic syndrome. Kidney Int 2002; 62 (2): 550-556</mixed-citation><mixed-citation xml:lang="en">Dogra GK, Watts GF, Herrmann S et al. Statin therapy improves brachial artery endothelial function in nephrotic syndrome. Kidney Int 2002; 62 (2): 550-556</mixed-citation></citation-alternatives></ref><ref id="cit175"><label>175</label><citation-alternatives><mixed-citation xml:lang="ru">Hausberg M, Kisters K, Kosch M et al. Flow-mediated vasodilation and distensibility of the brachial artery in renal allograft recipients. Kidney Int 1999; 55(3):1104-1109</mixed-citation><mixed-citation xml:lang="en">Hausberg M, Kisters K, Kosch M et al. Flow-mediated vasodilation and distensibility of the brachial artery in renal allograft recipients. Kidney Int 1999; 55(3):1104-1109</mixed-citation></citation-alternatives></ref><ref id="cit176"><label>176</label><citation-alternatives><mixed-citation xml:lang="ru">Asberg A, Holdaas H, Jardine AG et al. Fluvastatin reduces atherogenic lipids without any effect on native endothelial function early after kidney transplantation. Clin Transplantation 2003; 17(4): 385-391</mixed-citation><mixed-citation xml:lang="en">Asberg A, Holdaas H, Jardine AG et al. Fluvastatin reduces atherogenic lipids without any effect on native endothelial function early after kidney transplantation. Clin Transplantation 2003; 17(4): 385-391</mixed-citation></citation-alternatives></ref><ref id="cit177"><label>177</label><citation-alternatives><mixed-citation xml:lang="ru">Paisley KE, Beaman M, Tooke JE et al. Endothelial dysfunction and inflammation in asymptomatic proteinuria. Kidney Int 2003; 63(2): 624-631</mixed-citation><mixed-citation xml:lang="en">Paisley KE, Beaman M, Tooke JE et al. Endothelial dysfunction and inflammation in asymptomatic proteinuria. Kidney Int 2003; 63(2): 624-631</mixed-citation></citation-alternatives></ref><ref id="cit178"><label>178</label><citation-alternatives><mixed-citation xml:lang="ru">Hand MF, Haynes WG, Webb DJ. Hemodialysis and L-arginine, but not D-arginine, correct renal failure-associated endothelial dysfunction. Kidney Int 1998; 53(4): 1068-1073</mixed-citation><mixed-citation xml:lang="en">Hand MF, Haynes WG, Webb DJ. Hemodialysis and L-arginine, but not D-arginine, correct renal failure-associated endothelial dysfunction. Kidney Int 1998; 53(4): 1068-1073</mixed-citation></citation-alternatives></ref><ref id="cit179"><label>179</label><citation-alternatives><mixed-citation xml:lang="ru">London GM, Pannier B, Agharazii M et al. Forearm reactive hyperemia and mortality in end-stage renal disease. Kidney Int2004; 65(2): 700-705</mixed-citation><mixed-citation xml:lang="en">London GM, Pannier B, Agharazii M et al. Forearm reactive hyperemia and mortality in end-stage renal disease. Kidney Int2004; 65(2): 700-705</mixed-citation></citation-alternatives></ref><ref id="cit180"><label>180</label><citation-alternatives><mixed-citation xml:lang="ru">Pannier B, Guerin AP, Marchais SJ et al. Postischemic vasodilation, endothelial activation, and cardiovascular remodeling in end stage renal disease. Kidney Int 2000; 57(3): 1091-1097</mixed-citation><mixed-citation xml:lang="en">Pannier B, Guerin AP, Marchais SJ et al. Postischemic vasodilation, endothelial activation, and cardiovascular remodeling in end stage renal disease. Kidney Int 2000; 57(3): 1091-1097</mixed-citation></citation-alternatives></ref><ref id="cit181"><label>181</label><citation-alternatives><mixed-citation xml:lang="ru">Wang D, Iversen J, Wilcox CS, Strandgaard S. Endothelial dysfunction and reduced nitric oxide in resistance arteries in autosomal-dominant polycystic kidney disease. Kidney Int 2003; 64(4): 1381-1386</mixed-citation><mixed-citation xml:lang="en">Wang D, Iversen J, Wilcox CS, Strandgaard S. Endothelial dysfunction and reduced nitric oxide in resistance arteries in autosomal-dominant polycystic kidney disease. Kidney Int 2003; 64(4): 1381-1386</mixed-citation></citation-alternatives></ref><ref id="cit182"><label>182</label><citation-alternatives><mixed-citation xml:lang="ru">Al-Nimri MA, Komers R, Oyama TT et al. Endothelial-derived vasoactive mediators in polycystic kidney disease. Kidney Int 2003; 63(5):1776-1782</mixed-citation><mixed-citation xml:lang="en">Al-Nimri MA, Komers R, Oyama TT et al. Endothelial-derived vasoactive mediators in polycystic kidney disease. Kidney Int 2003; 63(5):1776-1782</mixed-citation></citation-alternatives></ref><ref id="cit183"><label>183</label><citation-alternatives><mixed-citation xml:lang="ru">Oflaz H, Turkmen A, Kazancioglu R et al. The effect of calcineurin inhibitors on endothelial function in renal transplant recipients. Clin Tranplantation 2003; 17(3): 212-217</mixed-citation><mixed-citation xml:lang="en">Oflaz H, Turkmen A, Kazancioglu R et al. The effect of calcineurin inhibitors on endothelial function in renal transplant recipients. Clin Tranplantation 2003; 17(3): 212-217</mixed-citation></citation-alternatives></ref><ref id="cit184"><label>184</label><citation-alternatives><mixed-citation xml:lang="ru">Annuk M, Zilmer M, Fellstrom B. Endothelium-dependent vasodilation and oxidative stress in chronic renal failure: Impact on cardiovascular disease. Kidney Int 2003; 63 [suppl 84]: 50-54</mixed-citation><mixed-citation xml:lang="en">Annuk M, Zilmer M, Fellstrom B. Endothelium-dependent vasodilation and oxidative stress in chronic renal failure: Impact on cardiovascular disease. Kidney Int 2003; 63 [suppl 84]: 50-54</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
