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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nefr</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology (Saint-Petersburg)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1561-6274</issn><issn pub-type="epub">2541-9439</issn><publisher><publisher-name>Pavlov First Saint-Petersburg State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/1561-6274-2003-7-1-46-50</article-id><article-id custom-type="elpub" pub-id-type="custom">nefr-989</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ. КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES. CLINICAL INVESTIGATIONS</subject></subj-group></article-categories><title-group><article-title>ГЛОМЕРУЛОНЕФРИТ КАК ФАКТОР, ОПРЕДЕЛЯЮЩИЙ ТЯЖЕСТЬ ТЕЧЕНИЯ ИНФЕКЦИОННОГО ЭНДОКАРДИТА</article-title><trans-title-group xml:lang="en"><trans-title>GLOMERULONEPHRITIS AS A FACTOR DETERMINING THE COURSE OF INFECTIOUS ENDOCARDITIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Синяченко</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sinyachenko</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра пропедевтики внутренних болезней</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аникеева</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Anikeeva</surname><given-names>T. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра пропедевтики внутренних болезней</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Игнатенко</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ignatenko</surname><given-names>G. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра пропедевтики внутренних болезней</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мильнер</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Milner</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра пропедевтики внутренних болезней</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ермолаева</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ermolaeva</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра пропедевтики внутренних болезней</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Такташов</surname><given-names>Г. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Taktashov</surname><given-names>G. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра пропедевтики внутренних болезней</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Донецкий государственный медицинский университет им. М. Горького</institution><country>Ukraine</country></aff><pub-date pub-type="collection"><year>2003</year></pub-date><pub-date pub-type="epub"><day>10</day><month>01</month><year>2003</year></pub-date><volume>7</volume><issue>1</issue><fpage>46</fpage><lpage>50</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Синяченко О.В., Аникеева Т.В., Игнатенко Г.А., Мильнер И.А., Ермолаева М.В., Такташов Г.С., 2003</copyright-statement><copyright-year>2003</copyright-year><copyright-holder xml:lang="ru">Синяченко О.В., Аникеева Т.В., Игнатенко Г.А., Мильнер И.А., Ермолаева М.В., Такташов Г.С.</copyright-holder><copyright-holder xml:lang="en">Sinyachenko O.V., Anikeeva T.V., Ignatenko G.A., Milner I.A., Ermolaeva M.V., Taktashov G.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephrolog.ru/jour/article/view/989">https://journal.nephrolog.ru/jour/article/view/989</self-uri><abstract><p>Поражение почек в виде гломерулонефрита выявленоу 52,2% больных инфекционным эндокардитом. У мужчин поражения как сердца, так и почек протекают более тяжело, относительно часто с развитием нефротического синдрома и почечной недостаточности. На тяжесть гломерулонефрита оказывают влияние длительность заболевания, первичный характер эндокардита, поражение отдельных структур сердца и экстракардиальные признаки болезни, а также сократительная способность миокарда. В свою очередь, степень тяжести почечной патологии определяет ряд электрофизиологических нарушений в сердце, гипертензию в малом круге кровообращения и общее периферическое сосудистое сопротивление.</p></abstract><trans-abstract xml:lang="en"><p>Glomerulonephritiswas diagnosed in 52% of patients with infectious endocarditis (IE). In males lesion both of the heart and of the kidneys has a more severe course and rather often the development of nephritic syndrome and kidney insufficiency is observed. The severity of glomerulonephritis is aggravated by the disease duration, primary character of IE and impaired structures of the heart and extracardial symptoms of the disease as well as the contractile ability of the myocardium. In its turn, the degree of the kidney pathology is responsible for a number of electrophysiological disorders in the heart, hypertension in the pulmonary circulation and total peripheral vascular resistance.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>инфекционный эндокардит</kwd><kwd>гломерулонефрит</kwd></kwd-group><kwd-group xml:lang="en"><kwd>infectious endocarditis</kwd><kwd>glomerulonephritis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Брусина Е.Б., Коломыщев А.Б., Барабаш О.Л., Бурматов Н.П. 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