THE CHANGES IN THE BLOOD FLOW CIRCULATION IN THE PROSTATE GLAND IN THE PATIENTS WITH BENIGN HYPERPLASIA IN TREATMENT WITH INHIBITORS OF 5-ALFA REDUCTASE (DUTASTERID)
https://doi.org/10.24884/1561-6274-2008-12-3-85-88
Abstract
THE AIM. To study the changes of indices of the prostate gland blood flow of the patients with the benign hyperplasia, during the treatment with Dutasterid. PATIENTS AND METHODS. 29 patients with benign hyperplasia of prostate gland (BHPG) (mean age 65, 21±6,27) were examined. In all patients by means of ultrasound and dopplerometry was examined the maximal systolic and final diastolic velocities of arterial blood flow, venal velocity, resistance index and pulsating index before the treatment, and also after 1, 3 and 6 month of treatment. RESULTS. The decrease of arterial and venous blood flow velocities in prostate gland, resistance index and pulsating index (p < 0,005), with its maximum in the first two month of treatment was noted. CONCLUSION. The use of Dutasterid in patients with BHPG during 1-2 month leads to statistically significant decrease in its blood flow, which allows to think about the decrease of blood loss during and after transurethral resection (TUR). The use of Dutasterid can serve as one of the stages of preoperative preparation of the patients with BHPG.
About the Authors
E. T. Goloshapov
Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова
Russian Federation
Russian Federation
G. B. Lukichev
Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова
Russian Federation
Russian Federation
N. U. Krukova
Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова
Russian Federation
Russian Federation
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Review
For citations:
Goloshapov E.T., Lukichev G.B., Krukova N.U. THE CHANGES IN THE BLOOD FLOW CIRCULATION IN THE PROSTATE GLAND IN THE PATIENTS WITH BENIGN HYPERPLASIA IN TREATMENT WITH INHIBITORS OF 5-ALFA REDUCTASE (DUTASTERID). Nephrology (Saint-Petersburg). 2008;12(3):85-88. (In Russ.) https://doi.org/10.24884/1561-6274-2008-12-3-85-88
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