Quality of life and long-term cardiovascular survival of patients on hemodialysis
Abstract
THE AIM. To test the hypothesis of the association of quality of life (QOL) scores with the risk of cardiovascular death in hemodialysis (HD) pts population. PATIENTS AND METHODS. Two hundred and fifty five prevalent HD pts were enrolled in the long-term prospective observational study. Patient’s baseline QOL scores assessed by SF-36 and clinical variables were measured to evaluate their relationships with cardiovascular death. Thirty nine pts whose causes of death remained unknown were excluded from the final analysis. The mean follow-up period was 65,7±48,3 months. RESULTS. Baseline scores of six QOL scales were significantly lower in the group of pts who died from cardiovascular complications during the follow-up period (n=71) compared with the combined group of those were alive or died from other causes. Differences in Mental Health and Role Emotional scores between groups were not significant. Physical Functioning score (PF) had a significant association with the risk of cardiovascular death in HD patients in multivariable Cox proportional-hazard model adjusted by other clinical confounders (ExpB (95% confidence interval) =0,987 (0,975-0,998), p=0,025). CONCLUSION. Physical Functioning score (PF) appeared to be the independent predictor of fatal cardiovascular events in the population of prevalent HD pts.
About the Authors
Vladimir A. Dobronravov
Research Institute of Nephrology, Scientific and Clinical Research Centre, Pavlov First Saint-Petersburg State Medical University; Pavlov First Saint-Petersburg State Medical University
Russian Federation
Russian Federation
Irina A. Vasilieva
Research Institute of Nephrology, Scientific and Clinical Research Centre, Pavlov First Saint-Petersburg State Medical University
Russian Federation
Russian Federation
Elena V. Babarykina
Omsk Regional Clinical Hospital
Russian Federation
Russian Federation
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Review
For citations:
Dobronravov V.A., Vasilieva I.A., Babarykina E.V. Quality of life and long-term cardiovascular survival of patients on hemodialysis. Nephrology (Saint-Petersburg). 2016;20(3):78-84. (In Russ.)
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