Litholytic therapy in the urate nephrolithiasis (clinical lecture)

Abstract

The lecture presents the prevalence of urolithiasis, the possible causes of incidence rate, role of uric acid metabolism disorders in the genesis of nephrolithiasis, pathological changes of kidneys due to metabolism disorders of uric acid. Therapy of kidney stones is not limited by calculi removal, and includes the correction of metabolism to prevent growth and recurrence of lithiasis. In this aspect, are considered inhibitors of xanthine oxidase, uricosuric medications, citrate drugs. A special place is given to the frequency and characteristics of urate nephrolithiasis, modern possibilities of its comprehensive diagnostics and therapy. Discussed in detail citrate litholytic therapy with individual selection of doses, the use of herbal remedies, dietary treatment, ways of urate nephrolithiasis prevention.