RENAL TUBULAR ACIDOSIS IN PRACTICE OF «ADULT» NEPHROLOGIST. COMMUNICATION 1. KIDNEYS ROLE IN ACID BASE HOMEOSTASIS REGULATION
https://doi.org/10.24884/1561-6274-2013-17-1-20-41
Abstract
This review briefly summarizes the current understanding about of acid-base transport in the kidney and the regulation of these processes. Attention was turned to range of questions which are deficiently observed in national science-medical literature: molecular structure of some transporters, involved in these processes, role of local pH, pCO2 and bicarbonate sensors, characteristics of gases transport through cell membranes etc. Was made an effort to show defects in which mechanisms of proton and bicarbonate translocation in renal tubules form the basis for rare and unique diseases – renal tubular acidosis.
About the Authors
I. G. Kayukov
Научно-исследовательский институт нефрологии, Санкт-Петербургский государственный медицинский университет
Russian Federation
Russian Federation
V. A. Dobronravov
Научно-исследовательский институт нефрологии, Санкт-Петербургский государственный медицинский университет
Russian Federation
Russian Federation
A. G. Kucher
Санкт-Петербургский государственный медицинский университет
Russian Federation
Russian Federation
A. M. Essaian
Санкт-Петербургский государственный медицинский университет
Russian Federation
Russian Federation
A. V. Smirnov
Научно-исследовательский институт нефрологии, Санкт-Петербургский государственный медицинский университет
Russian Federation
Russian Federation
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Kayukov I.G., Dobronravov V.A., Kucher A.G., Essaian A.M., Smirnov A.V. RENAL TUBULAR ACIDOSIS IN PRACTICE OF «ADULT» NEPHROLOGIST. COMMUNICATION 1. KIDNEYS ROLE IN ACID BASE HOMEOSTASIS REGULATION. Nephrology (Saint-Petersburg). 2013;17(1):20-41. (In Russ.) https://doi.org/10.24884/1561-6274-2013-17-1-20-41
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