APPLICATION OF DISCONTINUOUS NORMOBARIC HYPOXITHERAPY FOR TREATMENT OF HYPERTENSIVE SYNDROME IN PATIENTS WITH CHRONIC GLIMERULONEPHRITIS

Abstract

THE AIM of the investigation was to assess the hypotensive effectiveness of discontinuous normobaric hypoxitherapy and to study its influence on variability of arterial pressure and functional condition of the idneys n hypertensive patients with chronic glomerulonephritis. PATIENTS AND METHODS. The investigation included 26 patients (16 men and 10 women) divided into 3 groups. The first group consisted of 11 (42.3%) patients for treatment by discontinuous normobaric hypoxitherapy, the second group included 9 (34.6%) patients treated by hypoxitherapy in combination with the inhibitor of angiotensine converting enzyme, the third group included 6 (23.1%) patients treated with the inhibitor of angiotensine converting enzyme only. RESULTS. It was established that discontinuous normobaric hypoxitherapy possessed an independent hypotensive effect, potentiated when combined with the inhibitor of angiotensine converting enzyme, and also facilitated lowering daily proteinuria, reducing the frequency of unfavorable night-piker type of variability of arterial pressure, but does not influence the glomerular filtration rate. Transient tachycardia, dizziness and arterial hypotension are objectionable reactions of discontinuous normobaric hypoxitherapy. CONCLUSION. The data obtained suggest that discontinuous normobaric hypoxitherapy can occupy its place in therapy of hypertensive syndrome in chronic glomerulonephritis patients.