Hypercalciuria in children with the infection of the urinary system
Abstract
THE AIM. To study the metabolic abnormalities in children of Barnaul with the infection of the urinary system and to identify the relationship between the infection of the urinary system and idiopathic hypercalciuria. PATIENTS AND METHODS. The study included 49 children with the infection of the urinary system in age from 1 year to 14 years (42 girls and 7 boys, mean age 6,6 ± 3,7 years) hospitalized in nephrologic department of the «Town Children Hospital № 1» of Barnaul. All patients performed clinical examination and biochemical examination of blood and urine samples with a certain level of calcium, phosphor, creatinine, urea and uric acid levels, urine enzymes alkaline phosphatase, and gamma-glutamyl transferase, the urine calcium/creatinine ratio. RESULTS. In 49% of children revealed a combination the infection of the urinary system with metabolic disorders, with statistically significantly more frequently detected the calcium oxalate cristaluriya. Over 70% of children had the urine calcium/creatinine ratio greater than 0.2 indicating the idiopathic hypekalciuria. CONCLUSION. Urinary tract infection in children is often combined with idiopathic hypercalciuria indicating a need to define the daily excretion of calcium or calcium/creatinine in the urine of children with microbial and inflammatory diseases of the urinary system, and a decision on the correction of metabolic disorders.
About the Authors
N. M. Mikheeva
Алтайский государственный медицинский университет
Russian Federation
Russian Federation
YA. F. Zverev
Алтайский государственный медицинский университет
Russian Federation
Russian Federation
G. I. Vykhodceva
Алтайский государственный медицинский университет
Russian Federation
Russian Federation
YU. F. Lobanov
Алтайский государственный медицинский университет
Russian Federation
Russian Federation
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Review
For citations:
Mikheeva N.M., Zverev Ya.F., Vykhodceva G.I., Lobanov Yu.F. Hypercalciuria in children with the infection of the urinary system. Nephrology (Saint-Petersburg). 2014;18(1):74-79. (In Russ.)
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