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COMPLETE MODEL STEWART-FIGGE-FENCL IN OUTCOMES PREDICTING IN CARDIAC SURGERY PATIENTS WITH ACUTE KIDNEY INJURY TREATED BY CONTINUOUS RENAL REPLACEMENT THERAPY

Abstract

THE AIM: to evaluate the full model Stewart-Figge-Fencl parameters information value in adult cardiac patients with acute kidney injury (AKI) receiving continuous renal replacement therapy (RRT) and their suitability for stratification of adverse renal outcomes risk. PATIENTS AND METHODS: A retrospective cohort study was performed in 161 cardiac surgery patients from 21 to 80 years with dialysis-dependent AKI treated with continuous RRT. The parameters of a full model Stewart-Figge-Fencl including anion gap (Anion Gap), apparent and effective strong ion difference (Strong Ion Difference, «apparent», «effective») and strong ion gap (SIG) were analyzed. Using ROC- analysis, unmeasured ions were investigated as potential significant predictor's of in-hospital mortality and requirement for intermittent RRT after the continuous method termination. RESULTS. It was found that adult cardiac surgery patients with AKI characterized by the development of latent metabolic acidosis with increased anion gap, with a consequent reduction unmeasured ions for 2 days on background CRRT Specific patterns in the dynamics of unmeasured ions common to survivors and dead patients with AKI were detected. CONCLUSION: The appropriate and timely correction of unmeasured ions in patients with AKI, not only can improve a short-term but also long-term prognosis through reducing the need for intermittent renal replacement therapy after continuous RRT

About the Authors

S. V. Kolesnikov
Meshalkin State Research Institute of Circulation Pathology
Russian Federation


A. S. Borisov
Meshalkin State Research Institute of Circulation Pathology
Russian Federation


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Review

For citations:


Kolesnikov S.V., Borisov A.S. COMPLETE MODEL STEWART-FIGGE-FENCL IN OUTCOMES PREDICTING IN CARDIAC SURGERY PATIENTS WITH ACUTE KIDNEY INJURY TREATED BY CONTINUOUS RENAL REPLACEMENT THERAPY. Nephrology (Saint-Petersburg). 2015;19(4):74-81. (In Russ.)

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ISSN 1561-6274 (Print)
ISSN 2541-9439 (Online)