CHRONIC KIDNEY DISEASE PREDISPOSES TO ATRIAL FIBRILLATION IN PATIENTS WITH CHRONIC HEART FAILURE
https://doi.org/10.24884/1561-6274-2008-12-4-49-53
Abstract
THE AIM of the investigation was to certain the interrelation between the decrease of kidney function and atrial fibrillation (AF) in patients with chronic heart failure (CHF). PATIENTS AND METHODS. 340 patients with CHF (200 – male, 140 – female, mean age 58 ±13 years) were evaluated. The cause of CHF in 44 (13%) patients was arterial hyperpressure, in 122 (33%) – IHD, in 184 (54%) their combination. 66 (19%) had diabetes and 180 (53%) had myocardial infarction. The speed of glomerular filtration (SGF) was counted by MDRD formulae. 30 patients had paroxysmal/ persisting AF and 27 – persistent atrial fibrillation. RESULTS. SGF was 68, 8 ± 20,9 ml/min/1,73 m² (19,2 – 149,7 ml/min/1,73 m²) and in 114 (34%) patients it was < 60 ml/min/1,73 m². In most patients – 250 (74%) of the left ventricular ejection fraction stayed the same (EF > 50%). Patients with decreased kidney function had higher diameter of the left ventricular. SGF was lower in patients with AF, than without AF (58,8 ±14,2 against 69,1 ± 18,8 l/min/1,73m², accordingly, p<0.001). Logistical regression analysis showed that CKD (relative risk: 2,3: reliable interval: 95%; 1,2 – 4,3), functional class CHF (OR: 1,8; RI: 95%; 1,0[1]3,1) were independently associated with atrial fibrillation. CONCLUSION. So the presence of atrium fibrillation in patients with CHF is associated with decrease of the functional state of the kidneys – the patients with CKD should be perceived as patients at risk for the atrial fibrillation development.
About the Authors
A. M. Shutov
Ульяновский государственный университет
Russian Federation
Russian Federation
V. A. Serov
Ульяновский государственный университет
Russian Federation
Russian Federation
A. M. Gerdt
Ульяновский государственный университет
Russian Federation
Russian Federation
E. V. Kurzina
Ульяновский государственный университет
Russian Federation
Russian Federation
D. V. Serova
Ульяновский государственный университет
Russian Federation
Russian Federation
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Review
For citations:
Shutov A.M., Serov V.A., Gerdt A.M., Kurzina E.V., Serova D.V. CHRONIC KIDNEY DISEASE PREDISPOSES TO ATRIAL FIBRILLATION IN PATIENTS WITH CHRONIC HEART FAILURE. Nephrology (Saint-Petersburg). 2008;12(4):49-53. (In Russ.) https://doi.org/10.24884/1561-6274-2008-12-4-49-53
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