СОВРЕМЕННЫЕ ПРЕДСТАВЛЕНИЯ О РОЛИ ФИЗИКО-ХИМИЧЕСКИХ ФАКТОРОВ В ПАТОГЕНЕЗЕ КАЛЬЦИЕВОГО НЕФРОЛИТИАЗА
Аннотация
В обзоре приводится анализ современных взглядов на патогенез кальциевого нефролитиаза с позиций изменений ряда физико-химических параметров, в том числе, объемов потребляемой и выделяемой жидкости, пересыщения мочи определенными солями, верхней метастабильности и др. Приводятся сведения о действии таких природных ингибиторов кристаллизации как цитрат, магний, фитат, пирофосфат, которые рассматриваются в качестве перспективных средств профилактики рецидивов мочекаменной болезни.
Об авторах
Я. Ф. Зверев
Алтайский медицинский университет, г. Барнаул
Россия
Россия
кафедра фармакологии
656038, г.Барнаул, пр.Ленина, 40, тел.: (3852) 26-08-35
В. М. Брюханов
Алтайский медицинский университет, г. Барнаул
Россия
Россия
кафедра фармакологии
656038, г.Барнаул, пр.Ленина, 40, тел.: (3852) 26-08-35
В. В. Лампатов
Алтайский медицинский университет, г. Барнаул
Россия
Россия
кафедра фармакологии
656038, г.Барнаул, пр.Ленина, 40, тел.: (3852) 26-08-35
А. Ю. Жариков
Алтайский медицинский университет, г. Барнаул
Россия
Россия
кафедра фармакологии
656038, г.Барнаул, пр.Ленина, 40, тел.: (3852) 26-08-35
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Для цитирования:
Зверев Я.Ф., Брюханов В.М., Лампатов В.В., Жариков А.Ю. СОВРЕМЕННЫЕ ПРЕДСТАВЛЕНИЯ О РОЛИ ФИЗИКО-ХИМИЧЕСКИХ ФАКТОРОВ В ПАТОГЕНЕЗЕ КАЛЬЦИЕВОГО НЕФРОЛИТИАЗА. Нефрология. 2009;13(1):39-50. https://doi.org/10.24884/1561-6274-2009-13-1-39-50
For citation:
Zverev Y.P., Bryukhanov V.M., Lampatov V.V., Jaricov A.Yu. THE CURRENT VIEWS ON THE ROLE OF PHYSICO-CHEMICAL FACTORS IN PATHOGENESIS OF CALCIUM NEPHROLYTHIASIS. Nephrology (Saint-Petersburg). 2009;13(1):39-50. (In Russ.) https://doi.org/10.24884/1561-6274-2009-13-1-39-50
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