OXIDATIVE STRESS AND ITS PARTICIPATION IN NONIMMUNE MECHANISMS OF PROGRESSING CHRONIC KIDNEY DISEASE
https://doi.org/10.24884/1561-6274-2009-13-3-42-48
Abstract
Definition of a concept of «oxidative stress» is presented in the article, the most important oxidants and mechanisms of their injuring action are listed. Patterns of disorders connected with oxidative stress are discussed. Special attention is given to lipids as the main targets of oxidative processes in the organism, the markers of oxidative stress are named. General characteristic of the system of antioxidant protection of the organism, as well as characteristic of oxidants of different origin and mechanism of action is given. The importance of oxidative stress in pathogenesis of chronic kidney disease is discussed. The own findings of the authors are presented.
About the Authors
F. A. TugushevaRussian Federation
I. M. Zubina
Russian Federation
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Review
For citations:
Tugusheva F.A., Zubina I.M. OXIDATIVE STRESS AND ITS PARTICIPATION IN NONIMMUNE MECHANISMS OF PROGRESSING CHRONIC KIDNEY DISEASE. Nephrology (Saint-Petersburg). 2009;13(3):42-48. https://doi.org/10.24884/1561-6274-2009-13-3-42-48
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