SCREENING OF PROTEIN-ENERGY WASTING IN PATIENTS OF ST PETERSBURG DIALYSIS CENTERS
Abstract
THE AIM: to determine the diagnostic value of specific indicators for screening protein-energy wasting (PEW) in patients with chronic kidney disease (CKD) S5d, depending on comorbidity. PATIENTS AND METHODS. PEW screening was performed in 504 patients (46% women) aged 56,0±14,0 years in St. Petersburg dialysis centers. To reveal PEW we determined body mass index, creatinine serum concentration before hemodialysis, albumin and cholesterol serum content, calculated normalized protein catabolism rate. Index Charlson was used to assess the comorbidity. RESULTS. PEW signs met with varying frequency: serum creatinine concentration before HD less than 880 mcmol/l - 62%, albumin less than 38 g/l in 41%, total cholesterol less than 2.6 mmol/l in 2% patients. In accordance with normalized protein catabolism rate value less than 0.8 g/kg/day in 53% patients poor dietary protein intake was supposed. BMI less than 23 kg/m2 was registered in 26% patients. Regardless of which indicator was used, the presence of PEW was associated with more than 6 points Charlson index value. CONCLUSION. For PEW screening in patients with CKD S5d when serum creatinine before hemodialysis less than 880 mcmol/l or when Charlson index is more than 6 points we suggest to perform an instrumental examination to clarify the nature of PEW.
About the Authors
A. Sh. Rumyantsev
Pavlov First Saint Petersburg State Medical University; Saint Petersburg State University
Russian Federation
Russian Federation
K. A. Vishnevsky
Saint Petersburg State University; City hospital N15
Russian Federation
Russian Federation
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Review
For citations:
Rumyantsev A.Sh., Vishnevsky K.A. SCREENING OF PROTEIN-ENERGY WASTING IN PATIENTS OF ST PETERSBURG DIALYSIS CENTERS. Nephrology (Saint-Petersburg). 2015;19(6):34-38. (In Russ.)
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