PHYSICAL AND SEXUAL DEVELOPMENT OF ADOLESCENT GIRLS WITH RECURRENT URINARY TRACT INFECTIONS
https://doi.org/10.24884/1561-6274-2018-22-5-77-82
Abstract
THE AIM: to study the peculiarities of physical and sexual development of adolescent girls with recurrent urinary tract infections.
PATIENTS AND METHODS. Examined 70 adolescent girls aged 16 – 18 years with exacerbation of chronic pyelonephritis (CP): 1 group (n=43) – with rare relapse history (relapses pyelonephritis from 1 to 3 times during the period of the disease, rCP) and group 2 (n=27) with frequent relapses (more than 3 times a year, fCP). The control group (n=30) consisted of practically healthy adolescent girls of the same age. Anthropometry, evaluation of sexual development, specialized gynecological examination, determination of serum hormones, ultrasound examination of the reproductive organs were carried out. Statistical processing of research results was performed using the software packages Statistica 6.0 ("StatSoft Inc", USA) and statistical analysis Microsoft Office Excel 2003" ("Microsoft Corporation", USA).
RESULTS. It was revealed that in patients with rCP, compared with girls of the 1st and control groups, there was a lower growth, a decrease in the basic pelvic dimensions, against the background of a tendency to increase weight, there were some variants of sexual disorders, more often than in other groups there were early pubarche and later menarche. Established significant increase in the level of LH, testosterone and DHEA-S in the background of hypoprogesteronemia. The rate of hyperpolymenorrhea, uterine bleeding and primary oligomenorrhea was significantly higher, were often found emerging polycystic ovary syndrome and chronic vulvovaginitis.
CONCLUSION. Patients with frequent recurrence of urinary tract infections have a variety of constitutional features, a tendency to metabolic syndrome development, expressed hormonal status violations. The detected increase in testosterone levels contributes to the emerging polycystic ovaries syndrome development.
About the Authors
G. M. LetifovRussian Federation
Department of Pediatrics
344022, Russia, Rostov-on-don, the lane Nakhichevan, 29
Prof. Gadgy Letifov, MD, PhD, DMedSci
Phone: 8-909-438-11-13
Yu. Yu. Chebotareva
Russian Federation
Department of Obstetrics and Gynecology №2
344022, Russia, Rostov-on-don, the lane Nakhichevan, 29
Associate professor Julia Ju. Chebotareva, PhD, DMedSci
Phone: 8-928-100-60-55
E. G. Gorban’
Russian Federation
Department of Pediatrics
344022, Rostov-on-Don, Nakhichevansky 29
MD, postgraduate student
Phone: 8-908-186-47-32
Z. A. Kostoeva
Russian Federation
Department of Obstetrics and Gynecology №2
366130. Nazran, Ingushetia
Phone: 8-928-096-56-06
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Review
For citations:
Letifov G.M., Chebotareva Yu.Yu., Gorban’ E.G., Kostoeva Z.A. PHYSICAL AND SEXUAL DEVELOPMENT OF ADOLESCENT GIRLS WITH RECURRENT URINARY TRACT INFECTIONS. Nephrology (Saint-Petersburg). 2018;22(5):77-82. (In Russ.) https://doi.org/10.24884/1561-6274-2018-22-5-77-82