Antiphospholipid syndrome as acquired autoimmune thrombophilia in pediatric nephrology practice
Abstract
The article provides an overview of the literature on the etiology, pathogenesis, clinical and laboratory criteria, various options of antiphospholipid syndrome.
About the Authors
Ludmila P. Papayan
Russian Research Institute of Hematology and Transfusiology
Russian Federation
Russian Federation
Karina Albertovna Papayan
Saint-Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
References
1. Peterson LK, Willis R, Harris EN et al. Antibodies to Phosphatidylserine/Prothrombin Complex in Antiphospholipid Syndrome: Analytical and Clinical Perspectives. Adv Clin Chem 2016;73:1-28
2. Козловская НЛ, Захарова ЕВ, Зверев ДВ и др. Особенности поражения почек, обусловленного сочетанием гломерулонефрита и АФС-ассоциированной нефропатии при системной красной волчанке. Нефрология и диализ 2007; 9(4): 439-446 [Kozlovskajа NL, Zaharova EV, Zverev DV i dr. Osobennosti porazhenijа pochek, obuslovlennogo sochetaniem glomerulonefrita i AFS-associirovannoi nefropatii pri sistemnoi krasnoi volchanke. Nefrologijа i dializ 2007; 9(4): 439-446]
3. Chaturvedi S, Brandao L, Geary D, Licht C. Primary antiphospholipid syndrome presenting as renal vein thrombosis and membranous nephropathy. Pediatr Nephrol 2011; 26(6): 979-985
4. Папаян КА, Савенкова НД. Антифосфолипидный синдром в практике педиатра-нефролога. Тромбоз, гемостаз и реология 2014; 58(2):9-15 [Papajаn KA, Savenkova ND. Antifosfolipidnyi sindrom v praktike pediatra-nefrologa. Tromboz, gemostaz i reologijа 2014; 58(2):9-15]
5. Devreese K, Hoylaerts MF. Challenges in the diagnosis of the antiphospholipid syndrome. Clin Chem 2010 Jun;56(6):930-940
6. Кикнадзе КГ, Аббакумова ЛН, Калинина НМ, Новик ГА. Клинические особенности антифосфолипидного синдрома у детей. Лечащий врач 2010; 6:11-15 [Kiknadze KG, Abbakumova LN, Kalinina NM, Novik GA. Klinicheskie osobennosti antifosfolipidnogo sindroma u detei. Lechashii vrach 2010; 6:1115]
7. Hughes GR. Thrombosis, abortion, cerebral disease and lupus anticoagulant. Br Med J 1983; 287: 1088-1089
8. Bauman M, Massicotte MP, Yiu V. Disordered Hemostasis and Renal Disorders. In: Geary DF, Schaefer F, eds. Comprehensive pediatric nephrology. 1st ed. Mosby. 2008; 385-394
9. Rigante D, Gaspari S, Bersani G, Stabile A. Antiphospholipid syndrome; clinical spectrum and therapeutical/prophylactic strategies in the pediatric population. Eur Rev Med Pharmacol Sci 2008; 12 (1): 47-53
10. Improda N, Alessio M, Capalbo D et al. Acute adrenal failure as the presenting feature of primary antiphospholipid syndrome in a child. Ital J Pediatr 2012; 38:49-53
11. AvCin T Antiphospholipid syndrome in children. Cur Opin Rheumatol 2008; 20:595-600
12. Шитикова АС. Механизмы нарушения гемостаза при антифосфолипидном синдроме. Ученые записки СПбГМУ им. акад.И.П. Павлова 2004; 11(3): 47-59 [SHitikova AS. Mehanizmy narushenijа gemostaza pri antifosfolipidnom sindrome. Uchenye zapiski SPbGMU im. akad.I.P Pavlova 2004; 11(3): 47-59]
13. Constantin T, Ponyi A, Fekete G. Clinical relevance of antiphospholipid antibody tests in childhood. Eur J Pediatr 2004; 163:507-508
14. Nalli C, Piantoni S, Andreoli L et al. Antiphospholipid syndrome and antiphospholipid antibodies in children: the two sides of the coin. IMAJ 2012; 14: 310-312
15. De Laat B, Pengo V, Pabinger J et al. The association between circulating antibodies against domain I of beta2-glycopotein I and thrombosis: an international multicenter study. J Thromb Haemost 2009; 7:1767-1773
16. Баркаган ЗС, Момот АП, Сердюк ГВ, Цывкина ЛП. Основы диагностики и терапии антифосфолипидного синдрома. М. Ньюдиамед 2003; 48 [Barkagan ZS, Momot AP, Serdyuk GV, Cyvkina LP. Osnovy diagnostiki i terapii antifosfolipidnogo sindroma. M. N'yudiamed 2003; 48]
17. Папаян ЛП, Кобилянская ВА, Шитикова АС. Общие принципы диагностики антифосфолипидного синдрома. Ученые записки СПбГМУ им. акад.И.П. Павлова 2004; (3): 5962 [Papajаn LP, Kobiljаnskajа VA, SHitikova AS. Obshie principy diagnostiki antifosfolipidnogo sindroma. Uchenye zapiski SPbGMU im. akad.I.P. Pavlova 2004; (3): 59-62]
18. Turini RBF, Chechia TE, Fernandes TA et al. Antiphospholipid syndrome and thrombocytopenia in childhood. Rev Paul Pediatr 2012; 30 (3): 412-417
19. Avcin T, Cimaz R, Silverman ED et al. Pediatric antiphospholipid syndrome: clinical and immunologic features of 121 patients in an international registry. Pediatrics 2008; 122:1100-1107
20. Andreoli L, Nalli C, Motta M et al. Anti- ß2glycoprotein 1 IgG antibodies from 1-year old healthy children born to mothers with systemic autoimmune diseases preferentially target domain 4/5: might it be the reason for their «innocent» profile? Ann Rheum Dis 2011; 70:380-38
21. Avcin T, Toplak N. Antiphospholipid antibodies in response to infection. Curr Rheumatol Rep 2007; 9:212-218
22. Папаян КА, Капустин СИ, Федотова ЕП. Клиническое наблюдение синдрома антифосфолипидных антител и тромбофилии у пациента с волчаночным нефритом. Нефрология 2012; 16(3): 90-94 [Papajаn KA, Kapustin SI, Fedotova EP Klinicheskoe nablyudenie sindroma antifosfolipidnyh antitel i trombofilii u pacienta s volchanochnym nefritom. Nefrologijа 2012; 16(3): 90-94]
23. Erkan D, Cervera R, Asherson RA. Catastrophic antiphospholipid syndrome. Where do we stand? Arthritis Rheum 2003; 48:3320-3327
24. Noda S, Ogura M, Tsutsumi A, et al. Thrombotic microangiopathy due to multiple auto antibodies related to antiphospholipid syndrome. Pediatr Nephrol 2012; 27(4):681-685
25. Boffa M-C, Lachassine E. Infant perinatal thrombosis and antiphospholipid antibodies: a review. Lupus 2007; 16:634-641
26. Myones BL. Update on antiphospholipid syndrome in children. Curr Rheumatol Rep 2011; 13: 86-89
27. Lim W. Antiphospholipid antibody syndrome. Hematology 2009; 1:233-239
28. Marks SD, Tulus K. Lupus Nephritis. In: Geary DF, Schaefer F, eds. Comprehensive pediatric nephrology. 1st ed. Mosby 2008; 329-342
29. Козыро ИА, Сукало АВ. Новые маркеры в диагностике люпус-нефрита у детей (обзор литературы). Нефрология 2015; 19(3): 74-81 [Kozyro IA, Sukalo AV. Novye markery v diagnostike lyupus-nefrita u detei (obzor literatury). Nefrologijа 2015; 19(3): 74-81]
30. Joint European League Against Rheumatism & European Renal Association - European Dialisys and Transplant Association (EULAR/ERA-EDTA) Recommendations for the Management of Adult and Paediatric Lupus Nephritis. Ann Rheum Dis 2012; 71: 1771-1782
Review
For citations:
Papayan L.P., Papayan K.A. Antiphospholipid syndrome as acquired autoimmune thrombophilia in pediatric nephrology practice. Nephrology (Saint-Petersburg). 2016;20(3):9-16. (In Russ.)
Views:
618
Email this article 