Neurogenic bladder dysfunction in spina bifida: a case report and a brief review of the literature
N. V. Khudyakova,
I. Yu. Pchelin,
A. D. Kotrova,
A. N. Shishkin,
V. K. Bayrasheva,
V. V. Smirnov,
O. N. Vasilkova https://doi.org/10.36485/1561-6274-2022-26-4-119-126
Abstract
Spina bifida is a developmental defect of the spinal cord and/or spinal cord that results from abnormal closure of the embryonic neural tube. Many factors have been described to determine the risks of developing this pathology, but the incidence of the defect is still high. 61% of patients with spina bifida have neurogenic bladder dysfunction based on intravesical hypertension, which contributes to reverse urethral flow and vesico-uretero-renal reflux, associated with chronic inflammatory and obstructive diseases of the urinary tract. Between 25-50% of patients with spina bifida develop chronic kidney disease, significantly reducing their quality of life. In some types of Spina bifida, urological symptoms may be prominent and indicate the presence of this malformation. Therefore, early diagnosis of Spina bifida and timely prophylactic and therapeutic measures are particular importance. This article describes a clinical case of Spina bifida posterior L1-L2 with a closed L1-L2 meningocele in which urological symptoms were the dominant manifestation. The development of secondary complications of neurogenic bladder in the presented patient cannot be excluded, which requires closer monitoring.
About the Authors
N. V. Khudyakova
Saint-Petersburg State University
Russian Federation
Russian Federation
Khudiakova Natalia Valerevna, PhD, Associate Professor, Department of Faculty Therapy
199106
21 line VO 8a
St-Peterburg
tel.: +7 (812) 326-03-26
I. Yu. Pchelin
Saint-Petersburg State University
Russian Federation
Russian Federation
Pchelin Ivan Yurevich, PhD, Associate Professor, Department of Faculty Therapy
199106
21 line VO 8a
St-Peterburg
tel.: +7 (812) 326-03-26
A. D. Kotrova
Saint-Petersburg State University
Russian Federation
Russian Federation
Kotrova Anna Dmitrievna ,Junior Researcher, Department of Faculty Therapy
199106
21 line VO 8a
St-Peterburg
tel.: +7 (812) 326-03-26
A. N. Shishkin
Saint-Petersburg State University
Russian Federation
Russian Federation
Shishkin Alexander Nikolaevich, Prof. PhD, DMedSci, Associate Professor, Department of Faculty Therapy
199106
21 line VO 8a
St-Peterburg Phone: +7 (812) 326-03-26
V. K. Bayrasheva
Federal Almazov North-West Medical Research Centre, Institute of Endocrinology
Russian Federation
Russian Federation
Bayrasheva Valentina Kuzminichna, PhD, endocrinologist,
197341
15 Parkhomenko street
St-Peterburg
tel.: +7 (812) 702-55-73
V. V. Smirnov
Saint-Petersburg State Pediatric Medical University
Russian Federation
Russian Federation
Smirnov Victor Vladimirovich, Associate Professor, Department of hospital therapy with the course of endocrinology
194100
Litovskaya street 2
St-Peterburg
tel.: +7 9210958072
O. N. Vasilkova
Gomel State Medical University
Russian Federation
Russian Federation
Vasilkova Volha Nikolaevna, PhD, Associate Professor, Department of Internal Diseases No. 2
246000
Lange 5
Gomel
tel.: +37829 730-10-27
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Review
For citations:
Khudyakova N.V., Pchelin I.Yu., Kotrova A.D., Shishkin A.N., Bayrasheva V.K., Smirnov V.V., Vasilkova O.N. Neurogenic bladder dysfunction in spina bifida: a case report and a brief review of the literature. Nephrology (Saint-Petersburg). 2022;26(4):119-126. (In Russ.) https://doi.org/10.36485/1561-6274-2022-26-4-119-126
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