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Acute kidney injury of mild to moderate severity in patients with COVID-19
https://doi.org/10.36485/1561-6274-2024-28-2-37-42
EDN: TJBTMI
Abstract
THE AIM: to study the incidence of mild to moderate acute kidney injury in patients with COVID-19.
PATIENTS AND METHODS. The data of the case histories of 200 patients hospitalized in the infectious diseases department of the Naro-Fominsk Regional Hospital of the Moscow region for COVID-19 were analyzed, mainly with mild to moderate severity of lung damage according to computed tomography, which do not require respiratory support and renal replacement therapy.
RESULTS. Despite the fact that the analyzed group of patients did not have the most severe course of COVID-19, the first stage of acute kidney injury was detected in 22.5% of patients, which was manifested by a temporary decrease in hourly diuresis, increased creatinine, urea, proteinuria and erythrocyturia.
CONCLUSION. The development of acute kidney injury was most often associated with older age, coronary heart disease, arterial hypertension, diabetes mellitus and obesity.
About the Authors
E. N. Golovina
Department of transplantology, nephrology and artificial organs, Moscow Regional Research Clinical Institute name after M.F.Vladimirsky
Russian Federation
Russian Federation
Postgraduate student Golovina Elena Nikolaevna, MD
129110, Moscow, st.Shchepkina, 61/2
A. V. Vatasin
Department of transplantology, nephrology and artificial organs, Moscow Regional Research Clinical Institute name after M.F.Vladimirsky
Russian Federation
Russian Federation
Prof. Vatasin Andrey Vladimirovich, MD, PhD, DMed Sci
129110, Moscow, st.Shchepkina, 61/2
References
1. Sohrabi S, Alsafi Z, O'Neill N, Khan M, Kerwan A, Al-Jabir A et al. The World Health Organization declares a global emergency: a review of the new coronavirus 2019 (COVID-19). Int J Surg 2020;76:71–76
2. Shanmugaraj B, Malla A, Fulcharoen V. The emergence of a new coronavirus 2019-nCoV: the need for rapid development of vaccines and biological drugs. Pathogens 2020;9(2):148
3. Rotan HA, Reddy SN. Epidemiology and pathogenesis of the outbreak of coronavirus disease (COVID-19). J Is autoimmune 2020;109:102433
4. WHO (World Health Organization). Statement on the meeting of the Emergency Committee of the International Health Regulations (2005) in connection with the outbreak of a new coronavirus (2019-nCoV). Geneva, Switzerland: WHO Newsletter; 2020
5. da Silva SJR, de Magallanes JJF, Pena L. Simultaneous circulation of DENV, CHIKV, ZIKV and SARS-CoV-2 in Brazil: an inconvenient truth. Unified Health 2021;12:100205. 10.1016/j. onehlt.2020.100205
6. Bordi L, Nicastri E, Scorzolini L, Di Caro A, Capobianchi MR, Castilletti S, Lalle E. Differential diagnosis of the disease in patients under observation for a new coronavirus (SARS-CoV-2), Italy, February 2020. Eurosurveillance 2020;25(8):2000170
7. Yang G, Li KK, Lam LTM, Yang B, Chua YH, Lim AYN, Phang KF, Kyu GS, Teng H, Ngai KH, Lin L, Fu RM, Pada S, Ng LS, Tambia PA. Hidden COVID-19 and a false positive serological analysis for dengue in Singapore. Infection with the lancet Dis 2020;20(5):536. 10.1016/S1473-3099(20)30158-4
8. Wang K, Kang S, Tian R, Zhang H, Zhang X, Wang Y. Visualizing manifestations and diagnostic value of computed tomography of the chest in coronavirus disease 2019 (COVID-19) in Xiaogan district. Clinic. Radiol.
9. Safiabadi Tali SH, Leblanc JJ, Sadik Z, Oevunmi OD, Camargo S, Nikpour B, Armanfard N, Sagan SM, Jahanshahi-Anbukhi S. Tools and methods for detecting coronavirus 2 with severe acute respiratory syndrome (SARS-CoV-2) /COVID-19. Clinic Microbiol Editorial Office 2021;34(3):e00228-20 10.1128/CMR.00228-20
10. Udugama B, Kadiresan P, Kozlovsky HN, Malekjahani A, Osborn M, Lee VYK, Chen H, Mubareka S, Gubbai JB, Chan VKV. Diagnosis of COVID-19: disease and tools for detection. ACS Nano 2020;14(4):3822–3835. 10.1021/acsnano.0c02624
11. Cheng Yu, Luo R, Wang K, Zhang M, Wang Z, Dong L et al. Kidney disease is associated with the death of COVID-19 patients in the hospital. Kidneys 2020;97(5):829–838. doi: 10.1016/j.kint.2020.03.005
12. Minghao Ye, Jan Wysocki, William J, Soler MJ, Kokich I, Battle D. Localization in glomeruli and expression of angiotensin converting enzyme 2 and angiotensin converting enzyme: implications for albuminuria in diabetes. J Am Soc Нефрол 2006;17(11): 3067–3075. doi: 10.1681/ASN.2006050423
13. Ronko S, Reis T, Hussein-Syed F. Management of acute kidney injury in patients with COVID-19. Lancet Respir Med 2020;8(7):738–742. 10.1016/s2213-2600(20)30229-0
14. Ченг И, Луо Р, Ван К и др. Заболевание почек связано со смертью пациентов с COVID-19 в больнице. Почки Int 2020;97:829–838. 10.1016/j.kint.2020.03.005
15. Yalameha B, Roshan B, Lakkakula VK, Bhaskar ML. Views on the relationship between kidney disease and coronavirus disease in 2019. J Nephropharmacol 2020;9(2):e22. 10.34172/npj.2020.22
16. Kushlaa A, Buyakhya A. Nephropathy COVID-19; prob-able mechanisms of renal failure. J Nephropathol 2020;9:e35. 10.34172 /jnp.2020.35
17. Pan XW, Xu D, Zhang H, Zhou W, Wang LH, Cui XG. Identification of the potential mechanism of acute kidney injury during the COVID-19 outbreak: a study based on the analysis of a single cell transcriptome. Intensive care Med 2020;1–3. 10.1007/s00134-020-06026-1
18. Diao B, Feng Z, Wang S etc. The human kidney is a target for a new infection caused by coronavirus 2 with severe acute respiratory syndrome (SARS-CoV-2). Preparation for medRxiv 2020
19. Cheng Yi, Luo R, Wang K et al. Impaired renal function is associated with the death of patients with COVID-19 in the hospital. medRxiv 2020
20. Naiker S, Yang KV, Hwang SJ, Liu BK, Chen JH, Ja V. The new epidemic of coronavirus 2019 and kidneys. Kidneys Int 2020;97: 824–828. 10.1016/j.kint.2020.03.001
21. Sun J, Zhu A, Li H etc. Isolation of infectious SARS-CoV-2 from the urine of a patient with COVID-19. The germs of Emerg infect 2020;9:991–993
22. Qin S, Zhou L, Hu Z etc. Impaired regulation of the immune response in patients with COVID-19 in Wuhan, China. Clinical infectious disease 2020;71(15):762–768. 10.1093/ cid / ciaa248
23. Larsen SP, Born TD, Wilson DD, Sakka O, Sharshir MA. Collapsing glomerulopathy in a patient with coronavirus disease 2019 (COVID-19). International Kidney Conference 2020;5(6): 935–939. 10.1016/j.ekir.2020.04.002
24. Braun F, Lütgehetmann M, Pfefferle S, Wong MN, Carsten A, Lindenmeyer MT, Nörz D, Heinrich F, Meißner K, Wichmann D et al. Renal tropism of SARS-CoV-2 is associated with acute kidney injury. The Lancet 2020;396:597–598.4
25. Katsurakis A. COVID-19: endemic does not mean harmless. Nature 2022;601:485. doi: 10.1038/d41586-022-00155-x
26. Fischer M, Neugarten J, Bellin E, Younes M, Stahl L, Jones TS, Abramowitz MK, Levi R, Kumar N, Mokshitsky MH etc. AKI in hospitalized patients with and without COVID-19: a comparative study. J Am Soc Нефрол 2020;31: 2145–2157. doi: 10.1681/ASN.2020040509
27. Kolhe NV, Flak RJ, Selby NM, Taal MV. Acute kidney injury associated with COVID-19: a retrospective cohort study. PLoS Med 2020;17: e1003406. doi: 10.1371/journal.pmed.1003406
28. Silver SA, Beaubien-Suligny V, Shah PS, Harel S, Blum D, Kishibe T, Meraz-Munoz A, Wald R, Harel Z. Prevalence of acute kidney injury in patients hospitalized with COVID-19 infection: a systematic review and meta-analysis. Kidney medicine 2021;3:83–98.e1. doi: 10.1016/j.xkme.2020.11.008
29. Rumyantsev ASh, Khasun MKh, Panina IYu, Korosteleva NYu, Shurakova VA, Zemchenkov GA. Extracorporal hemocorrection methods for COVID-19: are there outlooks? Nephrology (Saint-Petersburg) 2021;25(4):95–106. (In Russ.) https://doi.org/10.36485/1561-6274-2021-25-4-95-106
Review
For citations:
Golovina E.N., Vatasin A.V. Acute kidney injury of mild to moderate severity in patients with COVID-19. Nephrology (Saint-Petersburg). 2024;28(2):37-42. (In Russ.) https://doi.org/10.36485/1561-6274-2024-28-2-37-42. EDN: TJBTMI
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