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THE EFFECT OF EARLY POSTTRANSPLANT PLASMAPHERESIS ON LATE RESULTS OF KIDNEYS GRAFTING IN CHILDREN

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Abstract

THE AIM: to estimate an influence of plasmapheresis (PA), carried in early postoperative period, on 15-year results of renal transplantation. PATIENTS AND METHODS. In 32 children operated at 1995-1996 years PA was not carried. This group was called “before PA”. In 32 children, operated at 1996-1997 years, PA was carried in early postoperative period. This group was called “PA”. In 31 patients operated at 1997-1998 years, PA was not carried, but their inductive immunosuppression was intensified with ATG, introduction of cyclosporine microemulsion and CellSept. This group was called “after PA”. RESULTS. Actuarial survival of both patients and grafts was highest in group “PA” and “after PA” compared to other groups. The difference was statistically significant. CONCLUSION: plasmapheresis done in the early posttransplant period may have a positive influence on long-term outcomes o f kidney transplantation in children.

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Kaabak M.M., Goryajnov V.A., Zokojev A.K., Babenko N.N., Vjyunkova Y.N., Morozova M.M., Aganesov A.G., Platova E.N., Dymova O.V., Panin V.V. THE EFFECT OF EARLY POSTTRANSPLANT PLASMAPHERESIS ON LATE RESULTS OF KIDNEYS GRAFTING IN CHILDREN. Nephrology (Saint-Petersburg). 2016;20(6):75-81. (In Russ.)

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ISSN 1561-6274 (Print)
ISSN 2541-9439 (Online)