Preview

Нефрология

Расширенный поиск

ОЖИРЕНИЕ И ЗАБОЛЕВАНИЯ ПОЧЕК: СКРЫТЫЕ ПОСЛЕДСТВИЯ ЭПИДЕМИИ

https://doi.org/10.24884/1561-6274-2017-21-2-10-19

Полный текст:

Аннотация

От имени Организационного Комитета Всемирного Дня Почки

Ожирение стало всемирной эпидемией, и, по прогнозам, его распространенность в ближайшем десятилетии увеличится на 40%. Растущая распространенность ожирения оказывает влияние на риск развития сахарного диабета, сердечно-сосудистых заболеваний, а также хронической болезни почек (ХБП). Высокий индекс массы тела – один из наиболее значимых факторов риска ХБП. У лиц с ожирением в ответ на увеличение метаболических потребностей избыточной массы тела развивается компенсаторная гиперфильтрация. Увеличение внутриклубочкового давления может привести к повреждению почек и повышению риска развития ХБП в отдаленном периоде. В последние годы частота развития гломерулопатии, ассоциированной с ожирением, выросла в 10 раз. Кроме того, показано, что ожирение является фактором риска нефролитиаза и ряда злокачественных новообразований, в том числе рака почки. В этом году Инициатива «Всемирный День Почки» выдвигает образовательную программу, которая разъясняет опасные последствия ожирения и его связь с заболеваниями почек, пропагандирует здоровый образ жизни и мероприятия по его формированию как доступную основу профилактики неблагоприятных последствий ожирения.

Об авторах

Чаба П. Ковесди
Университет Теннесси, Мемфис, Теннесси; Мемфисский Медицинский Центр Ветеранов Армии
Соединённые Штаты Америки
Отделение Нефрологии Медицинского факультета Научного Центра Здоровья Университета, Отдел Нефрологии Медицинского центра


Сьюзан Фурс
Университет Пенсильвании, Филадельфия, Пенсильвания
Соединённые Штаты Америки
Отделение Педиатрии Медицинской школа Перельмана


Кармин Зоккали
Институт Клинической Физиологии
Италия
Центр Научных Исследований Института, , Отдел Клинической Эпидемиологии и Патофизиологии Заболеваний Почек и Гипертензии, Калабрия


Список литературы

1. Forouzanfar MH, Alexander L, Anderson HR et al. Global, regional, and national comparative risk assessment of 79 behavioral, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 2015; 386:2287-2323

2. Flegal KM, Kruszon-Moran D, Carroll MD et al. Trends in Obesity Among Adults in the United States, 2005 to 2014. JAMA 2016;315:2284-2291

3. Cattaneo A, Monasta L, Stamatakis E et al. Overweight and obesity in infants and pre-school children in the European Union: a review of existing data. Obes Rev 2010; 11:389-398

4. Olaya B, Moneta MV, Pez O et al. Country-level and individual correlates of overweight and obesity among primary school children: a cross-sectional study in seven European countries. BMC Public Health 2015; 15:475

5. Subramanian SV, Perkins JM, Ozaltin E, Davey SG: Weight of nations: a socioeconomic analysis of women in low- to middleincome countries. Am J Clin Nutr 2011; 93:413-421

6. Tsujimoto T, Sairenchi T, Iso H et al. The dose-response relationship between body mass index and the risk of incident stage >/=3 chronic kidney disease in a general japanese population: the Ibaraki prefectural health study (IPHS). J Epidemiol 2014; 24:444-451

7. Elsayed EF, Sarnak MJ, Tighiouart H et al. Waist-to-hip ratio, body mass index, and subsequent kidney disease and death. Am J Kidney Dis 2008; 52:29-38

8. Pinto-Sietsma SJ, Navis G, Janssen WM et al. A central body fat distribution is related to renal function impairment, even in lean subjects. Am J Kidney Dis 2003; 41:733-741

9. Foster MC, Hwang SJ, Larson MG et al. Overweight, obesity, and the development of stage 3 CKD: the Framingham Heart Study. Am J Kidney Dis 2008; 52:39-48

10. Kramer H, Luke A, Bidani A et al. Obesity and prevalent and incident CKD: the Hypertension Detection and Follow-Up Program. Am J Kidney Dis 2005; 46:587-594

11. Chang A, Van HL, Jacobs DR et al. Lifestyle-related factors, obesity, and incident microalbuminuria: the CARDIA (Coronary Artery Risk Development in Young Adults) study. Am J Kidney Dis 2013; 62:267-275

12. Ejerblad E, Fored CM, Lindblad P et al. Obesity and risk for chronic renal failure. J Am Soc Nephrol 2006; 17:1695-1702

13. Gelber RP, Kurth T, Kausz AT et al. Association between body mass index and CKD in apparently healthy men. Am J Kidney Dis 2005; 46:871-880

14. Lu JL, Molnar MZ, Naseer A et al. Association of age and BMI with kidney function and mortality: a cohort study. Lancet Diabetes Endocrinol 2015;3:704-714

15. Munkhaugen J, Lydersen S, Wideroe TE, Hallan S: Prehypertension, obesity, and risk of kidney disease: 20-year follow-up of the HUNT I study in Norway. Am J Kidney Dis 2009; 54:638-646

16. Iseki K, Ikemiya Y, Kinjo K et al. Body mass index and the risk of development of end-stage renal disease in a screened cohort. Kidney Int 2004; 65:1870-1876

17. Vivante A, Golan E, Tzur D et al. Body mass index in 1.2 million adolescents and risk for end-stage renal disease. Arch Intern Med 2012; 172:1644-1650

18. Hsu C, McCulloch C, Iribarren C et al. Body mass index and risk for end-stage renal disease. Ann Intern Med 2006; 144:21-28

19. Lu JL, Kalantar-Zadeh K, Ma JZ et al. Association of body mass index with outcomes in patients with CKD. J Am Soc Nephrol 2014; 25:2088-2096

20. Thoenes M, Reil JC, Khan BV et al. Abdominal obesity is associated with microalbuminuria and an elevated cardiovascular risk profile in patients with hypertension. Vasc Health Risk Manag 2009;5:577-585

21. Kramer H, Gutierrez OM, Judd SE et al. Waist Circumference, Body Mass Index, and ESRD in the REGARDS (Reasons for Geographic and Racial Differences in Stroke) Study. Am J Kidney Dis 2016; 67:62-69

22. Foster MC, Hwang SJ, Massaro JM et al. Association of subcutaneous and visceral adiposity with albuminuria: the Framingham Heart Study. Obesity (Silver Spring) 2011; 19:1284-1289

23. Postorino M, Marino C, Tripepi G et al. Abdominal obesity and all-cause and cardiovascular mortality in end-stage renal disease. J Am Coll Cardiol 2009; 53:1265-1272

24. Kovesdy CP, Czira ME, Rudas A et al. Body mass index, waist circumference and mortality in kidney transplant recipients. Am J Transplant 2010; 10:2644-2651

25. Scales CD, Jr, Smith AC, Hanley JM et al. Prevalence of kidney stones in the United States. Eur Urol 2012; 62:160-165

26. Curhan GC, Willett WC, Rimm EB et al. Body size and risk of kidney stones. J Am Soc Nephrol 1998; 9: 1645-1652

27. Taylor EN, Stampfer MJ, Curhan GC: Obesity, weight gain, and the risk of kidney stones. JAMA 2005; 293:455-462

28. Bhaskaran K, Douglas I, Forbes H et al. Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5.24 million UK adults. Lancet 2014; 384:755-765

29. Arnold M, Pandeya N, Byrnes G et al. Global burden of cancer attributable to high body-mass index in 2012: a populationbased study. Lancet Oncol 2015; 16:36-46

30. Renehan AG, Tyson M, Egger M et al. Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies. Lancet 2008; 371:569-578

31. Bluher M: The distinction of metabolically 'healthy' from 'unhealthy' obese individuals. Curr Opin Lipidol 2010; 21:38-43

32. Sharma K: The link between obesity and albuminuria: adiponectin and podocyte dysfunction. Kidney Int 2009; 76:145-148

33. Wolf G, Ziyadeh FN: Leptin and renal fibrosis. Contrib Nephrol 2006; 151:175-183

34. Ellington AA, Malik AR, Klee GG et al. Association of plasma resistin with glomerular filtration rate and albuminuria in hypertensive adults. Hypertension 2007; 50:708-714

35. Bastard JP, Maachi M, Lagathu C et al. Recent advances in the relationship between obesity, inflammation, and insulin resistance. Eur Cytokine Netw 2006; 17:4-12

36. Furukawa S, Fujita T, Shimabukuro M et al. Increased oxidative stress in obesity and its impact on metabolic syndrome. J Clin Invest 2004; 114:1752-1761

37. Ruan XZ, Varghese Z, Moorhead JF: An update on the lipid nephrotoxicity hypothesis. Nat Rev Nephrol 2009; 5:713-721

38. Ruster C, Wolf G: The role of the renin-angiotensin-aldosterone system in obesity-related renal diseases. Semin Nephrol 2013; 33:44-53

39. Oterdoom LH, de Vries AP, Gansevoort RT et al. Fasting insulin modifies the relation between age and renal function. Nephrol Dial Transplant 2007; 22:1587-1592

40. Reaven GM: Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 1988; 37:1595-1607

41. Kambham N, Markowitz GS, Valeri AM et al. Obesityrelated glomerulopathy: an emerging epidemic. Kidney Int 2001; 59:1498-1509

42. de Vries AP, Ruggenenti P, Ruan XZ et al. Fatty kidney: emerging role of ectopic lipid in obesity-related renal disease. Lancet Diabetes Endocrinol 2014; 2:417-426

43. Foster MC, Hwang SJ, Porter SA et al. Fatty kidney, hypertension, and chronic kidney disease: the Framingham Heart Study. Hypertension 2011;58:784-790

44. Henegar JR, Bigler SA, Henegar LK et al. Functional and structural changes in the kidney in the early stages of obesity. J Am Soc Nephrol 2001; 12:1211-1217

45. Knight SF, Quigley JE, Yuan J et al. Endothelial dysfunction and the development of renal injury in spontaneously hypertensive rats fed a high-fat diet. Hypertension 2008; 51:352-359

46. Tsuboi N, Utsunomiya Y, Kanzaki G et al. Low glomerular density with glomerulomegaly in obesity-related glomerulopathy. Clin J Am Soc Nephrol 2012; 7:735-741

47. Ribstein J, du CG, Mimran A: Combined renal effects of overweight and hypertension. Hypertension 1995; 26:610-615

48. Maalouf NM, Sakhaee K, Parks JH et al. Association of urinary pH with body weight in nephrolithiasis. Kidney Int 2004; 65:1422-1425

49. Lemann J, Jr., Pleuss JA, Worcester EM et al. Urinary oxalate excretion increases with body size and decreases with increasing dietary calcium intake among healthy adults. Kidney Int 1996; 49:200-208

50. Siener R, Glatz S, Nicolay C, Hesse A: The role of overweight and obesity in calcium oxalate stone formation. Obes Res 2004; 12:106-113

51. Taylor EN, Stampfer MJ, Curhan GC: Diabetes mellitus and the risk of nephrolithiasis. Kidney Int 2005; 68:1230-1235

52. Klisic J, Hu MC, Nief V et al. Insulin activates Na(+)/H(+)exchanger 3: biphasic response and glucocorticoid dependence. Am J Physiol Renal Physiol 2002; 283:F532-F539

53. Chobanian MC, Hammerman MR: Insulin stimulates ammoniagenesis in canine renal proximal tubular segments. Am J Physiol 1987; 253:F1171-F1177

54. Daudon M, Lacour B, Jungers P: Influence of body size on urinary stone composition in men and women. Urol Res 2006; 34:193-199

55. Sinha MK, Collazo-Clavell ML, Rule A et al. Hyperoxaluric nephrolithiasis is a complication of Roux-en-Y gastric bypass surgery. Kidney Int 2007;72:100-107

56. Calle EE, Kaaks R. Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. Nat Rev Cancer 2004; 4:579-591

57. Dalamaga M, Diakopoulos KN, Mantzoros CS: The role of adiponectin in cancer: a review of current evidence. Endocr Rev 2012; 33:547-594

58. Lamas O, Marti A, Martinez JA. Obesity and immunocompetence. Eur J Clin Nutr 2002; 56 Suppl 3:S42-S45

59. Lim C, Savan R: The role of the IL-22/IL-22R1 axis in cancer. Cytokine Growth Factor Rev 2014; 25:257-271

60. Grivennikov SI, Greten FR, Karin M. Immunity, inflammation, and cancer. Cell 2010; 140:883-899

61. Kovesdy CP, Anderson JE, Kalantar-Zadeh K. Paradoxical association between body mass index and mortality in men with CKD not yet on dialysis. Am J Kidney Dis 2007; 49:581-591

62. Kalantar-Zadeh K, Kuwae N, Wu DY et al. Associations of body fat and its changes over time with quality of life and prospective mortality in hemodialysis patients. Am J Clin Nutr 2006; 83:202-210

63. Beddhu S, Pappas LM, Ramkumar N, Samore M. Effects of body size and body composition on survival in hemodialysis patients. J Am Soc Nephrol 2003; 14:2366-2372

64. Curtis JP, Selter JG, Wang Y et al. The obesity paradox: body mass index and outcomes in patients with heart failure. Arch Intern Med 2005; 165:55-61

65. Wilson DO, Rogers RM, Wright EC, Anthonisen NR: Body weight in chronic obstructive pulmonary disease. The National Institutes of Health Intermittent Positive-Pressure Breathing Trial. Am Rev Respir Dis 1989; 139:1435-1438

66. Escalante A, Haas RW, del R, I: Paradoxical effect of body mass index on survival in rheumatoid arthritis: role of comorbidity and systemic inflammation. Arch Intern Med 2005; 165:1624-1629

67. Kalantar-Zadeh K, Kilpatrick RD, Kuwae N, Wu DY: Reverse epidemiology: a spurious hypothesis or a hardcore reality? Blood Purif 2005; 23:57-63

68. Noori N, Kopple JD, Kovesdy CP et al. Mid-arm muscle circumference and quality of life and survival in maintenance hemodialysis patients. Clin J Am Soc Nephrol 2010; 5:2258-2268

69. Dekker FW, de MR, van Dijk PC et al. Survival analysis: time-dependent effects and time-varying risk factors. Kidney Int 2008; 74:994-997

70. Snyder JJ, Foley RN, Gilbertson DT et al. Body size and outcomes on peritoneal dialysis in the United States. Kidney Int 2003; 64:1838-1844

71. Lee PS, Sampath K, Karumanchi SA et al. Plasma gelsolin and circulating actin correlate with hemodialysis mortality. J Am Soc Nephrol 2009; 20:1140-1148

72. Horwich TB, Fonarow GC, Hamilton MA et al. The relationship between obesity and mortality in patients with heart failure. J Am Coll Cardiol 2001; 38:789-795

73. Stenvinkel P, Marchlewska A, Pecoits-Filho R et al. Adiponectin in renal disease: relationship to phenotype and genetic variation in the gene encoding adiponectin. Kidney Int 2004; 65:274-281

74. Mohamed-Ali V, Goodrick S, Bulmer K et al. Production of soluble tumor necrosis factor receptors by human subcutaneous adipose tissue in vivo. Am J Physiol 1999; 277:E971-E975

75. Rauchhaus M, Coats AJ, Anker SD: The endotoxinlipoprotein hypothesis. Lancet 2000; 356:930-933

76. Jandacek RJ, Anderson N, Liu M et al. Effects of yo-yo diet, caloric restriction, and olestra on tissue distribution of hexachlorobenzene. Am J Physiol Gastrointest Liver Physiol 2005; 288:G292-G299

77. Kramer HJ, Saranathan A, Luke A et al. Increasing body mass index and obesity in the incident ESRD population. J Am Soc Nephrol 2006; 17:1453-1459

78. Postorino M, Mancini E, D'Arrigo G, Marino C, Vilasi A, Tripepi G, Gallus S, Lugo A, Santoro A, Zoccali C: Body mass index trend in haemodialysis patients: the shift of nutritional disorders in two Italian regions. Nephrol Dial Transplant 2016; 31(10):1699-705

79. 2008-2013 Action Plan for the Global Strategy for the Prevention and Control of Noncommunicable Diseases. 2009. World Health Organization. Ref Type: Online Source

80. O'Donoghue DJ, Stevens PE. A decade after the KDOQI CKD/guidelines: a perspective from the United Kingdom. Am J Kidney Dis 2012; 60:740-742

81. Bolignano D, Zoccali C. Effects of weight loss on renal function in obese CKD patients: a systematic review. Nephrol Dial Transplant 2013; 28 Suppl 4:iv82-iv98

82. Chang Y, Ryu S, Choi Y et al. Metabolically Healthy Obesity and Development of Chronic Kidney Disease: A Cohort Study. Ann Intern Med 2016;164:305-312

83. Wing RR, Bolin P, Brancati FL et al. Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes. N Engl J Med 2013; 369:145-154

84. Mallamaci F, Ruggenenti P, Perna A et al. ACE inhibition is renoprotective among obese patients with proteinuria. J Am Soc Nephrol 2011; 22:1122-1128

85. Friedman AN, Wolfe B. Is Bariatric Surgery an Effective Treatment for Type II Diabetic Kidney Disease? Clin J Am Soc Nephrol 2016; 11:528-535

86. Chang AR, Chen Y, Still C et al. Bariatric surgery is associated with improvement in kidney outcomes. Kidney Int 2016; 90:164-171

87. Jamal MH, Corcelles R, Daigle CR et al. Safety and effectiveness of bariatric surgery in dialysis patients and kidney transplantation candidates. Surg Obes Relat Dis 2015; 11:419-423

88. Ahmadi SF, Zahmatkesh G, Ahmadi E et al. Association of Body Mass Index with Clinical Outcomes in Non-DialysisDependent Chronic Kidney Disease: A Systematic Review and Meta-Analysis. Cardiorenal Med 2015; 6:37-49


Для цитирования:


Ковесди Ч., Фурс С., Зоккали К. ОЖИРЕНИЕ И ЗАБОЛЕВАНИЯ ПОЧЕК: СКРЫТЫЕ ПОСЛЕДСТВИЯ ЭПИДЕМИИ. Нефрология. 2017;21(2):10-19. https://doi.org/10.24884/1561-6274-2017-21-2-10-19

For citation:


Kovesdy C., Furth S., Zoccali C. OBESITY AND KIDNEY DISEASE: HIDDEN CONSEQUENCES OF THE EPIDEMIC. Nephrology (Saint-Petersburg). 2017;21(2):10-19. (In Russ.) https://doi.org/10.24884/1561-6274-2017-21-2-10-19

Просмотров: 193


ISSN 1561-6274 (Print)
ISSN 2541-9439 (Online)