Generate QR code
Open Access
Subscription Access
Long-term consequences of COVID-19 for kidneys: a manageable complication or a time bomb?
https://doi.org/10.36485/1561-6274-2026-30-1-56-59
EDN: COOGZK
Abstract
The impact of COVID-19 on chronic kidney disease (CKD) has already been confirmed by researchers around the world. However, there is still insufficient data in the literature how the new coronavirus infection can affect kidney function without signs of CKD before. The aim of this study was to determine the relative risk of developing stages 4-5 CKD in patients who had COVID-19 and did not have signs of kidney damage before, depending on the severity of the coronavirus infection, the fact of hospitalization and the complication of acute kidney injury. The results of the study demonstrate that the development of late (4-5) stages of CKD can be directly associated with COVID-19, especially in patients with severe COVID-19, hospitalization or acute kidney injury, which is consistent with many studies in this area, in particular in patients without signs of CKD before.
About the Authors
V. A. Fedulkina
Moscow Regional Research Clinical Institute named after. M.F. Vladimirsky
Russian Federation
Russian Federation
Senior researcher Fedulkina Veronika Andreevna, MD, PhD, surgical department of kidney transplantation
129110, Moscow, st. Shchepkina, 61/2
Tel.: 8(495)684-57-91
A. A. Artamonova
Moscow Regional Research Clinical Institute named after. M.F. Vladimirsky
Russian Federation
Russian Federation
Senior researcher Artamonova Alexandra Anatolyevna, MD, PhD, surgical department of kidney transplantation
129110, Moscow, st. Shchepkina, 61/2
Tel.: 8(495)684-57-91
A. B. Zulkarnaev
Moscow Regional Research Clinical Institute named after. M.F. Vladimirsky
Russian Federation
Russian Federation
Major researcher. Zulkarnaev Alexey Batirgaraevich, MD, DMedSci, surgical department of kidney transplantation
129110, Moscow, st. Shchepkina, 61/2
Tel.: 8(495)684-57-91
References
1. CDC COVID-19 Response Team. Preliminary Estimates of the Prevalence of Selected Underlying Health Conditions Among Patients with Coronavirus Disease 2019 – United States. February 12 – March 28. Weekly 2020;69(13):382–386. doi:10.15585/mmwr.mm6913e2
2. Guan WJ, Ni ZY, Hu Y et al. China Medical Treatment Expert Group for Covid-19. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med 2020;382(18):1708–1720. doi: 10.1056/NEJMoa2002032
3. COVID-19 Surveillance Group. Characteristics of COVID-19 patients dying in Italy: report based on available data on March 20th, 2020. Rome, Italy: Instituto Superiore Di Sanita; 2020 [Internet]. Available from: https://www.epicentro.iss.it/coronavirus/bollettino/Report-COVID-2019_20_marzo_eng.pdf
4. Kravchenko AYa, Kontsevaya AV, Budnevsky AV, Chernik TA. Novel coronavirus infection (COVID-19) and kidney disease. Profilakticheskaya Meditsina 2022;25(3):92–97. (In Russ.) doi: 10.17116/profmed20222503192
5. Henry BM, Lippi G. Chronic kidney disease is associated with severe coronavirus disease 2019 (COVID-19) infection. International Urology and Nephrology 2020;52(6):1193–1194. doi: 10.1007/s11255-020-02451-9/
6. Suleyman G, Fadel RA, Malette KM et al. Clinical Characteristics and Morbidity Associated with Coronavirus Disease 2019 in a Series of Patients in Metropolitan Detroit. JAMA Network Open 2020;3(6):e2012270. doi: 10.1001/jamanetworkopen.2020.12270
7. Tomilina NA, Frolova NF, Artyuhina LYU et al. COVID-19: relationship with kidney diseases. Literature review. Nephrology and dialysis 2021; 23(2):147–159. (In Russ.) doi: 10.28996/2618-9801-2021-2-147-159
8. Duarsa GWK, Sugianto R, Yusari IGAAA et al. Method for determining predictor factor for worse outcomes in kidney transplant recipients infected with coronavirus disease 2019 in a systematic review and meta-analysis research. MethodsX 2023;11:102250. doi: 10.1016/j.mex.2023.102250
9. Ghaffari Rahbar M, Nafar M, Khoshdel A et al. Low rate of COVID-19 pneumonia in kidney transplant recipients-A battle between infection and immune response? Transpl Infect Dis 2020;22(5):e13406. doi: 10.1111/tid.13406
10. Caillard S, Anglicheau D, Matignon M et al. French SOT COVID Registry. An initial report from the French SOT COVID Registry suggests high mortality due to COVID-19 in recipients of kidney transplants. Kidney Int 2020;98(6):1549–1558. doi: 10.1016/j.kint.2020.08.005
11. Santeusanio AD, Menon MC, Liu C et al. Influence of patient characteristics and immunosuppressant management on mortality in kidney transplant recipients hospitalized with coronavirus disease 2019 (COVID-19). Clin Transplant 2021;35(4):e14221. doi: 10.1111/ctr.14221
12. Cheng Y, Luo R, Wang K et al. Kidney disease is associated with in-hospital death of patients with COVID-19. Kidney Int 2020;97(5):829–838. doi: 10.1016/j.kint.2020.03.005
13. Sun S, Annadi RR, Chaudhri I et al. Short- and Long-Term Recovery after Moderate/Severe AKI in Patients with and without COVID-19. Kidney360 2021;3(2):242–257. doi: 10.34067/KID.0005342021
14. Hirsch JS, Ng JH, Ross DW et al. Northwell COVID-19 Research Consortium; Northwell Nephrology COVID-19 Research Consortium. Acute kidney injury in patients hospitalized with COVID-19. Kidney Int 2020;98(1):209–218. doi: 10.1016/j.kint.2020.05.006
15. Richardson S, Hirsch JS, Narasimhan M et al. Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area. JAMA 2020;323(20):2052–2059. doi: 10.1001/jama.2020.6775
16. Temiz MZ, Hacibey I, Yazar RO et al. Altered kidney function induced by SARS-CoV-2 infection and acute kidney damage markers predict survival outcomes of COVID-19 patients: a prospective pilot study. Ren Fail 2022;44(1):233–240. doi: 10.1080/0886022X.2022.2032743
17. Filev R, Rostaing L, Lyubomirova M et al. COVID-19 Infection in Chronic Kidney Disease Patients in Bulgaria: Risk Factors for Death and Acute Kidney Injury. J Pers Med 2022;12(10):1676. doi: 10.3390/jpm12101676
18. Oynotkinova OSh, Matskeplishvili ST, Larina VN et al. The effect of SARS-CoV-2 on multi-organ damage and rehabilitation tactics in the post-COVID period. Kardiologiya i Serdechno-Sosudistaya Khirurgiya 2022;15(2):202–214. (In Russ.) doi: 10.17116/kardio202215021202
19. Borisova OV, Makovetskaya GA, Mazur LI et al. COVID-19 pandemic and kidney disease in children: literature review and own regional observations. Meditsinskiy sovet 2022;(1):134–141. (In Russ.) doi: 10.21518/2079-701X-2022-16-1-134-141
20. Nurullina GI, Khalfina TN, Islamova et al. Clinical case of acute kidney injury in a patient with COVID-19. Practical medicine 2022;20(1):129–132. (In Russ.) doi: 10.32000/2072-1757-2022-1-129-132
21. Ivanov DD, Gozhenko AI, Ivanova MD, Zavalnaya IN. Effect of COVID-19 on kidney function in patients with arterial hypertension grade 1-2 and CKD. Nephrology (Saint-Petersburg) 2022;26(1):34–43. (In Russ.) doi: 10.36485/1561-6274-2022-26-1-34-43
Review
For citations:
Fedulkina V.A., Artamonova A.A., Zulkarnaev A.B. Long-term consequences of COVID-19 for kidneys: a manageable complication or a time bomb? Nephrology (Saint-Petersburg). 2026;30(1):56-59. (In Russ.) https://doi.org/10.36485/1561-6274-2026-30-1-56-59. EDN: COOGZK
Views:
160
JATS XML
Email this article 